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ADAM28

  • Official Full Name

    ADAM metallopeptidase domain 28

  • Overview

    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform. [provided by RefSeq, Jul 2008]
  • Synonyms

    ADAM28; ADAM metallopeptidase domain 28; MDCL; MDC-L; ADAM23; MDC-Lm; MDC-Ls; eMDCII; ADAM 28; eMDC II; disintegrin and metalloproteinase domain-containing protein 28; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADAM28-212H Active Recombinant Human ADAM28 protein, His-tagged CHO His
Human ADAM28-3002H Recombinant Human ADAM28, His-tagged E.coli His 775
Human ADAM28-3003H Recombinant Human ADAM28 protein, His-tagged E.coli His Glu525-Lys774
Human ADAM28-9036HCL Recombinant Human ADAM28 293 Cell Lysate HEK293 N/A
Human ADAM28-9037HCL Recombinant Human ADAM28 293 Cell Lysate HEK293 N/A
Mouse ADAM28-1292M Recombinant Mouse ADAM28 Protein Mammalian Cell His
Mouse ADAM28-316M-B Recombinant Mouse ADAM28 Protein Pre-coupled Magnetic Beads HEK293
Mouse ADAM28-316M Recombinant Mouse ADAM28 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ADAM28-4560Z Recombinant Zebrafish ADAM28 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ADAM28 Related Articles
  • ADAM28 Related Research Area

ADAM28 involved in several pathways and played different roles in them. We selected most pathways ADAM28 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ADAM28 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM28 itself. We selected most functions ADAM28 had, and list some proteins which have the same functions with ADAM28. You can find most of the proteins on our site.

Function Related Protein
metalloendopeptidase activityADAM17A;FAP;ADAM10B;ADAM2;ADAM33;BMP1B;ADAMTS13;ADAM5P;BMP1
metallopeptidase activityADAM21;GM5136;NPEPPS;DPP3;STAMBPL1;AQPEP;CLCA1;BMP1A;ADAM1B
zinc ion bindingRARAB;ZDHHC14;RARG;TRIM31;NR1D4A;XIAP;SRSF7;TRIM12A;NHLRC1

ADAM28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM28 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM28.

bosutinib; imatinib

Abe, H; Mochizuki, S; et al. Src Plays a Key Role in ADAM28 Expression in v-src-Transformed Epithelial Cells and Human Carcinoma Cells. AMERICAN JOURNAL OF PATHOLOGY 183:1667-1678(2013).
Mochizuki, S; Soejima, K; et al. Effect of ADAM28 on Carcinoma Cell Metastasis by Cleavage of von Willebrand Factor. JOURNAL OF THE NATIONAL CANCER INSTITUTE 104:906-922(2012).
  • Q&As
  • Reviews

Q&As (13)

Ask a question
Do you offer ADAM28 protein with other tags? 10/28/2022

We can customize ADAM28 with other tags according to your needs.

Is it possible to customize the production of ADAM28 protein with specific purity? 09/11/2022

Yes, we can customize the production of specific purity proteins according to your needs.

How should I make my ADAM23 selection based on the characteristics of these different expression systems? 09/03/2022

You can consult directly with our experts for questions related to product selection.

What are the two sub-types of ADAM28? 12/01/2021

The classical transmembrane form ADAM28m and the shorter absence of transmembrane secretion form ADAM28s.

Is ADAM28 protein participating in this promotion? What if I have a custom request? 11/09/2021

This product is participating in this promotion and custom-produced proteins are eligible.

Can I customize a tag other than His? 05/12/2021

Yes, you can talk to our experts about your specific customization needs.

Can the location of His tag be customized? 04/16/2021

Yes, you can communicate directly with our experts about your customization needs.

Is ADAM28 protein hydrophilic or hydrophobic? 04/10/2021

ADAM28 protein is hydrophilic.

Where is the cellular localization of ADAM28? 01/02/2021

ADAM28 is a transmembrane secretory glycoprotein localized on the cell surface.

Is ADAM28 widely used in disease research? 10/19/2020

ADAM28 has been used in studies of lung, breast and colon cancers.

Does ADAM28 bind with neuronal secretory protein? 08/23/2020

ADAM28 interacts with the neuronal secretory protein LGI1.

In which human tissues is ADAM28 highly expressed? 07/14/2020

ADAM28 is mainly expressed on the surface of spleen, lymph nodes and peripheral blood lymphocytes.

I would like to purchase ADAM28 for WB. You offer several different ADAM28 proteins, how do I choose? 06/21/2020

You can consult directly with our experts, who will be able to advise on the selection based on your specific study.

Customer Reviews (5)

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Reviews
11/06/2022

    The salesperson was very patient and answered every question in a serious and timely manner when I was purchasing protein products.

    01/26/2022

      Bought a protein product at a promotional price, it's a great price.

      04/10/2021

        The technical staff often communicate with me to understand the progress of my experiments and give timely responses to problems encountered in the experiments.

        03/01/2021

          The ADAM28 protein received was of stable composition and high concentration, giving me satisfactory experimental results.

          06/30/2020

            The company provides one-stop service, from product purchase to product delivery, it was very smooth.

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