adam28
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  • Official Full Name
  • ADAM metallopeptidase domain 28
  • Background
  • This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform. [provided by RefSeq, Jul 2008]
  • Synonyms
  • ADAM28; ADAM metallopeptidase domain 28; MDCL; MDC-L; ADAM23; MDC-Lm; MDC-Ls; eMDCII; ADAM 28; eMDC II; disintegrin and metalloproteinase domain-containing protein 28; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II;
Cat.#:ADAM28-212HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human ADAM28 protein, His-tagged
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Cat.#:ADAM28-3002HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADAM28, His-tagged
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Cat.#:ADAM28-3003HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADAM28 protein, His-tagged
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Cat.#:ADAM28-1292MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ADAM28 Protein
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Cat.#:ADAM28-4560ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ADAM28
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Cat.#:ADAM28-9036HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ADAM28 293 Cell Lysate
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Cat.#:ADAM28-9037HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ADAM28 293 Cell Lysate
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Protein Function

ADAM28 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM28 itself. We selected most functions ADAM28 had, and list some proteins which have the same functions with ADAM28. You can find most of the proteins on our site.
Function
Related Protein
Function metalloendopeptidase activity
Related Protein ADAMTS1; ADAMTS12; MMP7; ADAM15; ADAMTS8; KEL; ECE2; BMP1A; PMPCB; ADAM9
Function metallopeptidase activity
Related Protein ADAM23; MMP9; XPNPEP3; ANPEPB; PAPLNB; AGBL1; XPNPEP2; ADAM8A; ADAMTS1; LNPEP
Function zinc ion binding
Related Protein OAS2; NSMCE1; ADAMTS3; RXRBB; NSD1; RXRGB; KDM2BA; TRIM3B; TOP3A; WTIP

Interacting Protein

ADAM28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM28 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM28.
bosutinib; imatinib

ADAM28 Related Articles

Abe, H; Mochizuki, S; et al. Src Plays a Key Role in ADAM28 Expression in v-src-Transformed Epithelial Cells and Human Carcinoma Cells. AMERICAN JOURNAL OF PATHOLOGY 183:1667-1678(2013).
Mochizuki, S; Soejima, K; et al. Effect of ADAM28 on Carcinoma Cell Metastasis by Cleavage of von Willebrand Factor. JOURNAL OF THE NATIONAL CANCER INSTITUTE 104:906-922(2012).