adcy7
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  • Official Full Name
  • adenylate cyclase 7
  • Background
  • This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.
  • Synonyms
  • ADCY7; adenylate cyclase 7; adenylate cyclase type 7; AC7; KIAA0037; adenylyl cyclase 7; ATP pyrophosphate-lyase 7; adenylate cyclase type VII; FLJ36387
Cat.#:ADCY7-3180HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human ADCY7, His-tagged
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Cat.#:ADCY7-331HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADCY7 Protein, GST-tagged
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Cat.#:ADCY7-476HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human ADCY7
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Cat.#:ADCY7-6932HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADCY7 protein, His & T7-tagged
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Cat.#:Adcy7-3179MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Adcy7, His-tagged
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Cat.#:Adcy7-6933MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Adcy7 protein, His & T7-tagged
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Cat.#:ADCY7-7608ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ADCY7
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Involved Pathway

ADCY7 involved in several pathways and played different roles in them. We selected most pathways ADCY7 participated on our site, such as Activation of GABAB receptors, Adenylate cyclase activating pathway, Adenylate cyclase inhibitory pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of GABAB receptors
GNGT2B; KCNJ9; ADCY9; KCNJ2; GNB3A; KCNJ5; KCNJ2A; KCNJ4; KCNJ3; KCNJ12
Adenylate cyclase activating pathway
ADCY3; ADCY6; ADCY9; ADCY8; ADCY1; ADCY7
Adenylate cyclase inhibitory pathway
ADCY7; ADCY9; ADCY8; ADCY3; ADCY6; ADCY1
Adrenergic signaling in cardiomyocytes
PPP2R1B; GNA11A; ADCY9; TNNT2; ADRB3A; PPP2R5A; CALML3; RYR2; MAPK14; CALM3B
Aldosterone synthesis and secretion
CALML3; PRKD3; CYP21A2; PLCB1; CREB3L3; NPR1; PRKACG; PLCB3; CALML5; ORAI1
Aquaporin-mediated transport
AQP10B; MIPA; ADCY1; AQP10; AQP1A.2; AQP9B; AQP11; GNB3B; AQP6; ADCY8
Bile secretion
ATP1B4; OSTA; ATP1A4; SLCO1A6; ADCY3; SLC22A8; SLC4A4; PRKACA; SLC2A1; ATP1B1
Ca-dependent events
ADRBK1; PRKAR1AA; ADCY9; ADCY7

Protein Function

ADCY7 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY7 itself. We selected most functions ADCY7 had, and list some proteins which have the same functions with ADCY7. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein Adcy4; HSP90AA1.1; ACVR2AA; UCK2; RPS6KA3B; ACTA2; GM711; GTF2F2B; KLHL8; EPHB2B
Function adenylate cyclase activity
Related Protein ADCY1A; ADCY6; ADCY1B; ADCY1; ADCY3; ADCY7; ADCY9; ADCY2B; Adcy4; GNAS
Function metal ion binding
Related Protein ZNF219; ZNF26; CXXC1A; STAC3; CYP51; NUDT8; TSHZ1; ZNF263; GUCA1B; CACNA1H

Interacting Protein

ADCY7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY7.
PLSCR1; XRCC6; BUD31

ADCY7 Related Articles

Patocka, N; Sharma, N; et al. Serotonin Signaling in Schistosoma mansoni: A Serotonin-Activated G Protein-Coupled Receptor Controls Parasite Movement. PLOS PATHOGENS 10:-(2014).
Knospe, M; Muller, CE; et al. The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative ligand binding site. PURINERGIC SIGNALLING 9:367-381(2013).