adh6
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  • Official Full Name
  • alcohol dehydrogenase 6 (class V)
  • Background
  • This gene encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This gene is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5 UTR, which is a steroid hormone receptor binding site. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • ADH6; alcohol dehydrogenase 6 (class V); alcohol dehydrogenase 6; ADH 5; ADH 6; Aldehyde reductase; Class V alcohol dehydrogenase 6; UDP GLUCURONOSYLTRANSFERASE 2B10 PRECURSOR, MICROSOMAL; OTTHUMP00000161647; OTTHUMP00000161648; OTTHUMP00000161649; OTTHUMP00000220107; ADH-5
Cat.#:ADH6-1365HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ADH6 Protein, MYC/DDK-tagged
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Cat.#:ADH6-2405HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Alcohol Dehydrogenase 6 (class V), His-tagged
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Cat.#:ADH6-351HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ADH6 Protein, GST-tagged
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Cat.#:ADH6-525RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ADH6 Protein
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Cat.#:ADH6-6649CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ADH6
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Cat.#:ADH6-31HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ADH6 cell lysate
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Involved Pathway

ADH6 involved in several pathways and played different roles in them. We selected most pathways ADH6 participated on our site, such as Biological oxidations, Chemical carcinogenesis, Drug metabolism - cytochrome P450, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADH6 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Biological oxidations
SLC35D1A; CYP51A1; SULT2ST1; CYP2C18; GLYAT; SULT2ST2; SULT1ST6; CYP2U1; CYP2J2; NAT2
Chemical carcinogenesis
UGT1A4; CYP3A4; CYP2C8; Nat3; CYP2C50; CYP3A7; CYP2C9; CYP3A41B; GSTM5; CYP2C39
Drug metabolism - cytochrome P450
ADH7; ADH5; ADH1B; ADH1C; CYP2E1; ADH1A; CYP2C8; CYP2C9; CYP2D6; ADH2-2
Ethanol oxidation
ADH8B; ADH7; ADH1A; ADH6; ADH1C; ADH4; ADH8A; ADH1B; ADH5
Fatty Acid Omega Oxidation
ADH6; CYP2E1; ADH1C; ADH7; ADH1A; CYP2D6; CYP2A6; CYP1A1; ADH1B; ADH4
Fatty acid degradation
ADH6; ACSL1; CPT2; HADHA; ACSL1A; ADH1A; ALDH1B1; ACSL5; ACSL4A; EHHADH
Glycolysis / Gluconeogenesis
ADH6; ADH1B; PFKP; PDHA1B; HK2; ADH2-1; G6PCA.2; ALDH2; ALDOAB; TPI1
Metabolic pathways
COX10; PLA2G4D; GLCEA; NDUFA6; SEPHS2; AGXT; PDHA1B; IDI2; INPP4B; PAPSS2A

Protein Function

ADH6 has several biochemical functions, for example, alcohol dehydrogenase (NAD) activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADH6 itself. We selected most functions ADH6 had, and list some proteins which have the same functions with ADH6. You can find most of the proteins on our site.
Function
Related Protein
Function alcohol dehydrogenase (NAD) activity
Related Protein ADH4; ADH8A; DHRS9; ADH8B; ADH1C; ADH1A; ADH5; ADH7; ADH6; ADH1
Function zinc ion binding
Related Protein ADAMTS1; CPSF4; MUL1A; NR2E1; ADAM17A; DHH; GCH1; PRICKLE1; SEC24A; MICALL2

Interacting Protein

ADH6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADH6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADH6.
TNIP1; ANKRD17; RSL1D1; KRAS; ARRB1; RPS29; RPAIN; RASSF5