AK8 Protein, adenylate kinase 8

AK8

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AK8

Official Full Name adenylate kinase 8
Background Adenylate kinase (EC 2.7.4.3) (also known as ADK or myokinase) is a phosphotransferase enzyme that catalyzes the interconversion of adenine nucleotides, and plays an important role in cellular energy homeostasis.
Synonyms DDX31; C9orf98; FLJ32704; FLJ36014; RP11-143F18.1; adenylate kinase 8; OTTHUMP00000022737; putative adenylate kinase-like protein C9orf98
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AK8-0225H Recombinant Human AK8 Protein, GST-Tagged Wheat Germ GST
    Human AK8-264HCL Recombinant Human AK8 cell lysate N/A
    Mouse AK8-1468M Recombinant Mouse AK8 Protein Mammalian Cell His
    Rat AK8-586R Recombinant Rat AK8 Protein Mammalian Cell His
    Cynomolgus Monkey AK8-288C Recombinant Cynomolgus AK8 Protein, His-tagged Mammalian Cell His
    Zebrafish AK8-2817Z Recombinant Zebrafish AK8 Mammalian Cell His

    AK8 involved in several pathways and played different roles in them. We selected most pathways AK8 participated on our site, such as Biosynthesis of antibiotics, Metabolic pathways, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AK8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biosynthesis of antibiotics ACAA2; EHHADH; CS; ECHS1; ADSL; ANI_1_2390104; LDHAL6B; AK8; SDS; ADH5
    Metabolic pathways CYP4F14; COX11; PRPS2; DGKE; NAPRT1; GCNT3; DPYS; SPTLC2B; CHIA; AGLA
    Metabolism LMF2; SLC6A8; ETFA; DLAT; CYP11B1; ACOT9.2; B3GNT1; INSIG1; TREH; ETFB
    Metabolism of nucleotides ADSS; NUDT18; NUDT15; AK7; DHODH; ADSSL1; AK8; TYMP; DPYS; ITPA
    Purine metabolism GUCY1A3; NME2; POLR2D; NPR2; POLR1E; POLR3GLB; ENTPD8; POLR1C; ENPP1; NME6
    Synthesis and interconversion of nucleotide di- and triphosphates AK7; AK7A; GRX2; AK8; DTYMK; GLRX
    adenosine ribonucleotides de novo biosynthesis AK8; ATP5S; ADSSL1; ADSS; AK7; ATP5L
    purine nucleotides de novo biosynthesis ATP5S; AK8; AK7; ADSSL1

    AK8 has several biochemical functions, for example, ATP binding, adenylate kinase activity, cytidylate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AK8 itself. We selected most functions AK8 had, and list some proteins which have the same functions with AK8. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding HSPA1B; MAPK6; PPP1CA; EPHA10; MYO1G; AARS2; LRRK2; KIF26A; cka1; PIP4K2C
    adenylate kinase activity AK8; AK4; AK1; AK5; AK7; AK2
    cytidylate kinase activity AK8; CMPK; CMPK1; AK7; CMPK2
    nucleoside diphosphate kinase activity TXNDC3; NME3; NME9; AK8; CMPK2; CMPK; NME2B.1; AK4; AK1; NME7
    protein binding MAP4K3; RIPK4; C5orf24; MEF2C; SCAMP5; CLSTN2; BANP; TUBA3E; LYRM2; SIAH1

    AK8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AK8 here. Most of them are supplied by our site. Hope this information will be useful for your research of AK8.

    CCDC102B; MCM7; MAP3K7CL; RBM39; RBM39; HAUS1; ZMAT2

    Grueb, M; Rohrbach, JM; et al. Serotonin (5-HT7) Receptor-Stimulated Activation of cAMP-PKA Pathway in Bovine Corneal Epithelial and Endothelial Cells. OPHTHALMIC RESEARCH 48:22-27(2012).
    Moteki, H; Kimura, M; et al. Activation of Extracellular-Signal Regulated Kinase by Epidermal Growth Factor Is Potentiated by cAMP-Elevating Agents in Primary Cultures of Adult Rat Hepatocytes. BIOLOGICAL & PHARMACEUTICAL BULLETIN 34:1542-1552(2011).

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