akap9
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  • Official Full Name
  • A kinase (PRKA) anchor protein (yotiao) 9
  • Background
  • The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.
  • Synonyms
  • AKAP9; A kinase (PRKA) anchor protein (yotiao) 9; A-kinase anchor protein 9; A kinase anchor protein; 350kDa; A kinase anchoring protein 450; AKAP9 BRAF fusion protein; AKAP120 like protein; AKAP350; AKAP450; centrosome and golgi localized protein; CG NAP; HYPERION; KIAA0803; kinase N associated protein; MU RMS 40.16A; PPP1R45; PRKA9; protein kinase A anchoring protein 9; protein phosphatase 1; regulatory subunit 45; YOTIAO; protein yotiao; protein hyperion; AKAP 120-like protein; AKAP9-BRAF fusion protein; kinase N-associated protein; A-kinase anchor protein 350 kDa; A-kinase anchor protein 450 kDa; protein phosphatase 1, regulatory subunit 45; centrosome- and Golgi-localized PKN-associated protein; AKAP-9; CG-NAP; MU-RMS-40.16A
Cat.#:AKAP9-26527THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AKAP9, His-tagged
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Cat.#:AKAP9-405HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AKAP9 Protein, GST-tagged
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Cat.#:AKAP9-7119CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AKAP9
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Involved Pathway

AKAP9 involved in several pathways and played different roles in them. We selected most pathways AKAP9 participated on our site, such as ARMS-mediated activation, Activation of NMDA receptor upon glutamate binding and postsynaptic events, Anchoring of the basal body to the plasma membrane, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ARMS-mediated activation
SLC14A2; JAK2; SPTBN2; MARK3; KLB; DUSP1; PSMD5; CSK; CSF2RA; PEA15
Activation of NMDA receptor upon glutamate binding and postsynaptic events
PDPK1A; AKAP9; ADCY3; CAMKK1B; ADCY8; CREB1B; NETO2; DLG4; ADCY1; CREB1
Anchoring of the basal body to the plasma membrane
CEP152; CSNK1E; MARK4; MAPRE1A; DCTN1; CDK5RAP2; MKS1; TUBG1; ACTR1A; DCTN1A
Assembly of the primary cilium
CEP57; WDR19; CCT3; CNGA5; CEP76; CKAP5; CCT4; SSTR3; CP110; IFT81
Axon guidance
COL4A5; SEMA6D; CHL1; EPHA7; ST8SIA2; PHB; ABL1; DCX; EPHA10; CFL1
CREB phosphorylation through the activation of CaMKII
DLG4; NETO2; AKAP9; SLC14A2; NEFLB; CREB1B
CREB phosphorylation through the activation of Ras
AKAP9; SLC14A2; NEFLB; PDPK1A; DLG4
Cell Cycle
SMC4; USO1; ORC3; NEK9; TGFB1A; TEX15; CCNA2; YWHABL; CDK7; CEP164

Protein Function

AKAP9 has several biochemical functions, for example, ion channel binding, potassium channel regulator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP9 itself. We selected most functions AKAP9 had, and list some proteins which have the same functions with AKAP9. You can find most of the proteins on our site.
Function
Related Protein
Function ion channel binding
Related Protein YWHAQ; CALM; SRC; VDAC1; PIRT; LRRK2; DIAP1; RYR2; TRPC1; KCNQ1
Function potassium channel regulator activity
Related Protein DPP10; KCNMB3; KCNS3; KCNMB1; YWHAE; NEDD4L; ARPP19; KCNIP4; SUMO1; ARPP19A
Function protein binding
Related Protein STON2; LCE1B; TALDO1; SEC14L4; ARAF; ECT2; GABPB1; SEPT11; HILPDA; HTR3E
Function protein complex scaffold
Related Protein WWC2; CHCHD3; CNOT1; C9orf142; MAP2K2; CAV1; DLG1; WWC1; MPP7; SLC9A3R2
Function protein kinase A regulatory subunit binding
Related Protein ARFGEF2; ACBD3; AKAP8; EZR; AKAP6; C2orf88; PJA2; AKAP9; AKAP7; KCNQ1
Function receptor binding
Related Protein HAND2; BMP2; UFD1L; RSPO2; NPFFL; FGF13B; DRD1A; CNPY3; PTK2; C1QTNF2

Interacting Protein

AKAP9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP9 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP9.
GOLGA2; KDM1A; p29991-pro_0000037946; ORF; PSTPIP1; ELF3; SMYD2; ACTR3B; PUF60; TULP3; TDP2; C1orf94; pbuO; q81mm5_bacan; ybgA