aldh3b2
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  • Official Full Name
  • aldehyde dehydrogenase 3 family, member B2
  • Background
  • This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.
  • Synonyms
  • ALDH3B2; aldehyde dehydrogenase 3 family, member B2; ALDH8; aldehyde dehydrogenase family 3 member B2; acetaldehyde dehydrogenase 8; aldehyde dehydrogenase 8; OTTHUMP00000235616
Cat.#:ALDH3B2-448HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ALDH3B2 Protein, GST-tagged
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Cat.#:ALDH3B2-497HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Aldehyde Dehydrogenase 3 Family, Member B2, GST-tagged
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Cat.#:ALDH3B2-498HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Aldehyde Dehydrogenase 3 Family, Member B2, His-tagged
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Cat.#:ALDH3B2-59HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ALDH3B2 cell lysate
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Involved Pathway

ALDH3B2 involved in several pathways and played different roles in them. We selected most pathways ALDH3B2 participated on our site, such as Glycolysis / Gluconeogenesis, Histidine metabolism, Tyrosine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH3B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycolysis / Gluconeogenesis
ACSS2; LDHBA; PFKP; ADH6; PCK1; ALDOC; ALDH3A2A; ADH4; PGM1; MINPP1B
Histidine metabolism
UROC1; ALDH9A1B; ALDH7A1; HNMT; ALDH2; ASPA; ALDH9A1; ALDH3A2A; ALDH2.2; ALDH3B1
Tyrosine metabolism
ALDH3A1; DBH; TYRP1; TPO; GOT2A; AOX2P; HPDA; TYR; HPD; HGD
Phenylalanine metabolism
HPDA; AOC2; KEG1; IL4I1; GM4952; MAOB; PAH; GOT2B; GOT2; ALDH3B1
beta-Alanine metabolism
ALDH9A1A.1; CNDP1; ALDH1B1; ALDH1A3; ALDH2; CARNS1; ALDH6A1; ALDH3B2; ALDH9A1B; HADHAA
Metabolism of xenobiotics by cytochrome P
UGT1A9; UGT2B7; ADH1; ALDH3A1; EPHX1; GSTM7; GSTA3; UGT1AB; MGST1.2; GSTA2
Drug metabolism - cytochrome P
ALDH3B1; GSTM1; GSTM4; ALDH3B2; ALDH3A1; FMO2; ALDH1A3; UGT1AB; MGST2; FMO3
Metabolic pathways
GALT; UPP2; CYP7A1; BCAT2; AMY1A; PNLIP; ST6GAL1; NME2B.1; R05D11.9; PNPLA3
Chemical carcinogenesis
UGT2B15; CYP3A4; UGT1A7C; SULT1A2; GSTT2; GSTA4; GSTA2; UGT1A2; UGT1A4; SULT1A4

Protein Function

ALDH3B2 has several biochemical functions, for example, 3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, aldehyde dehydrogenase [NAD(P)+] activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH3B2 itself. We selected most functions ALDH3B2 had, and list some proteins which have the same functions with ALDH3B2. You can find most of the proteins on our site.
Function
Related Protein
Function 3-chloroallyl aldehyde dehydrogenase activity
Related Protein ALDH9A1; ALDH1A1; ALDH3B2; ALDH3A1; ALDH3A2B; ALDH3A2A; ALDH2.1; ALDH3A2; Aldh1a7; ALDH3B1
Function aldehyde dehydrogenase (NAD) activity
Related Protein ALDH3B2; ALDH1A3; ALDH1B1; ALDH9A1B; ALDH9A1A.1; ALDH16A1; ALDH6A1; ALDH9A1; ALDH8A1; ALDH3A1
Function aldehyde dehydrogenase [NAD(P)+] activity
Related Protein ALDH1A3; ALDH3A1; ALDH3A2B; ALDH3B2; ALDH3B1; ALDH3A2; ALDH2; ALDH3A2A

ALDH3B2 Related Articles

Hartomo, TB; Pham, TVH; et al. Involvement of aldehyde dehydrogenase 1A2 in the regulation of cancer stem cell properties in neuroblastoma. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1089-1098(2015).
Zhang, RL; Miao, Q; et al. Genome-wide DNA methylation analysis in alcohol dependence. ADDICTION BIOLOGY 18:392-403(2013).
Holmes, RS; Hempel, J; et al. Comparative studies of vertebrate aldehyde dehydrogenase 3: Sequences, structures, phylogeny and evolution. Evidence for a mammalian origin for the ALDH3A1 gene. CHEMICO-BIOLOGICAL INTERACTIONS 191:113-121(2011).
Holmes, RS; et al. Biochemical Genetics of Opossum Aldehyde Dehydrogenase 3: Evidence for Three ALDH3A-Like Genes and an ALDH3B-Like Gene. BIOCHEMICAL GENETICS 48:287-303(2010).