ANK2 Protein, Ankyrin 2, Neuronal


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Official Full Name Ankyrin 2, Neuronal
Background Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton. Ankyrins have binding sites for the beta subunit of spectrin and at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane.
Synonyms ANK2; ankyrin 2, neuronal; LQT4; ANK-2; brank-2; ankyrin-2; ankyrin B; ankyrin, brain; non-erythroid ankyrin; ankyrin-2, non-erythrocytic; Brain ankyrin; long (electrocardiographic) QT syn-drome 4; DKFZp686M09125; FLJ38277; OTTHUMP00000163833; OTTHUMP00000163834; OTTHUMP00000220392; OTTHUMP00000220393; OTTHUMP00000220397; OTTHUMP00000220398; OTTHUMP00000231464; ankyrin, nonerythroid; Ankyrin-B
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Ank2-429M Recombinant Mouse Ank2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human ANK2-2077H Recombinant Human ANK2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse ANK2-1645M Recombinant Mouse ANK2 Protein Mammalian Cell His

    ANK2 involved in several pathways and played different roles in them. We selected most pathways ANK2 participated on our site, such as Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteoglycans in cancer FASLG; GAB1; WNT2B; MMP2; MAPK1; MAP2K1; HRAS; RPS6KB2; WNT9A; AKT1

    ANK2 has several biochemical functions, for example, ATPase binding, ion channel binding, potassium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ANK2 itself. We selected most functions ANK2 had, and list some proteins which have the same functions with ANK2. You can find most of the proteins on our site.

    Function Related Protein
    ion channel binding FXYD1; SRI; FKBP1B; ANK2; AKAP9; SCN3B; GPD1L; SCN5A; ASPH; CALM1
    potassium channel regulator activity KCNAB2; KCNE2; DRD4; KCNV1; AKAP9; KCNIP4; KCNIP3; NEDD4L; CHP; KCNMB4
    protein binding TYROBP; NFKBIL2; MSH4; PSMC1; TBP; DOCK9; PLEKHF1; WIBG; HCLS1; C1orf50
    protein binding, bridging FGA; FLRT1; CUX1; TIRAP; PPP4R2; CSTA; FSCN2A; ADAP2; NCK1; FLRT2

    ANK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANK2.

    Sptan1; Kif3a; SNCA; Ywhae; Ywhaz; Kifap3; Ywhab; Actg1; Dctn4

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