Aox4
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Official Full Name
aldehyde oxidase 4
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Arabidopsis thaliana (Mouse-ear cress)
- Mouse
- Rat
- E.coli expression system
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Mouse | AOX4-1728M | Recombinant Mouse AOX4 Protein | Mammalian Cell | His | ||
Mouse | AOX4-594M | Recombinant Mouse AOX4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | AOX4-594M-B | Recombinant Mouse AOX4 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | AOX4-697R | Recombinant Rat AOX4 Protein | Mammalian Cell | His | ||
Rat | AOX4-353R-B | Recombinant Rat AOX4 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | AOX4-353R | Recombinant Rat AOX4 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Arabidopsis thaliana (Mouse-ear cress) | RFL15447AF | Recombinant Full Length Arabidopsis Thaliana Alternative Oxidase 4, Chloroplastic/Chromoplastic(Aox4) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (57-351) |
- Involved Pathway
- Protein Function
- Interacting Protein
- Aox4 Related Signal Pathway
Aox4 involved in several pathways and played different roles in them. We selected most pathways Aox4 participated on our site, such as Valine, leucine and isoleucine degradation, Tyrosine metabolism, Tryptophan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Aox4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Valine, leucine and isoleucine degradation | AACS;BCAT2;HADHAB;ACAT1;HMGCL;ALDH9A1B;ACAT2;HMGCS2;HIBADH |
Tyrosine metabolism | AOX3;PNMT;DCT;GOT2A;ADH2-1;ALDH3A1;AOX2P;MIF;AOX4 |
Tryptophan metabolism | CYP1A;ALDH2.2;ALDH3A2;HADH;HADHAB;AOX3L1;GCDHA;AANAT;ASMT |
Vitamin B metabolism | PSAT1;AOX4;AOX3L1;AOX3;AOX2P;PNPO;PDXP;PHOSPHO2;PDXKA |
Nicotinate and nicotinamide metabolism | QPRT;NAMPTB;NT5M;NT5C3L;NT5C1A;NT5C2A;NAPRT;PNP;NNMT |
Retinol metabolism | RDH10A;BCO1L;SDR16C5A;LRAT;UGT1A6B;CYP3A25;UGT2A3;AOX3;UGT1AB |
Drug metabolism - cytochrome P | UGT5G1;MGST1;GSTT2B;UGT2A1;MGST3;ALDH3A1;UGT1A1;AOX1;AOX2P |
Metabolic pathways | DNMT3B;CKMT1B;SCP2;POLE;QDPRB2;TYMS;FAH;GRHPR;PYGM |
Jak-STAT signaling pathway | Ifna15;PIK3CB;JAK2B;CNTFR;SOCS3;FHL1B;IFNA21;IL12RB1;CISH |
Aox4 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding, NAD binding, aldehyde oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Aox4 itself. We selected most functions Aox4 had, and list some proteins which have the same functions with Aox4. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
2 iron, 2 sulfur cluster binding | GLRX5;CISD2;XDH;FXN;AOX4;SDHB;AIFM3;ISCA1;NDUFS1 |
NAD binding | CTBP1;ADH1;GPD1A;SORD;HPGD;HSD3B4;PARP1;HADHA;LDHA |
aldehyde oxidase activity | AOX3L1;ADH7;AOX1;AOX4;AOX3 |
catalytic activity | THA1;PNP5A;PHKA1;NRD1B;PPM1DB;AZIN1B;ETNPPL;LDHBA;TIGARB |
electron carrier activity | ACAD11;NDUFS3;UGDH;TXNRD1;AKR1A1;ACADS;GCDHB;MAOB;NDUFS6 |
flavin adenine dinucleotide binding | POR;GCDHB;AIFM3;CRY-DASH;FMO5;SDHA;AIFM2;SQLE;AOX3 |
iron ion binding | CALR;CYP2C54;CYGB1;CYP4A10;SC5D;CYP2K16;ALOX15;CYP2C19;ALOX5A |
iron-sulfur cluster binding | FXN;AOX3;NFS1;ISCUB;AOX3L1;AIFM4;CMAH;RSAD1;FDX1B |
metal ion binding | ZNF143A;NT5DC1;NADK;ZNF454;ZNF529;ZBTB9;ZNF274;GALNT11;TIPARP |
molybdenum ion binding | MOCOS;MARC1;SUOX;MOSC2;AOX3;AOX4;MARC2 |
oxidoreductase activity | SDR42E1;IYD;KDM5BB;CYP8B2;HPDB;CYP46A1.3;VAT1;ADH1;DEGS1 |
oxidoreductase activity, acting on CH-OH group of donors | DHCR24;AOX3;XDH;AGPS;AOX4;GULO;AOX3L1;AOX1 |
Aox4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Aox4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Aox4.
- Q&As
- Reviews
Q&As (16)
Ask a questionThe change of AOX4 is related to oxidative stress in the body, such as the release of oxygen free radicals and hydrogen peroxide, which is the main reason for the change of AOX4. Some diseases, infections, pain and other conditions may also cause changes in AOX4.
AOX4 is a protein found in human blood serum.
The external environment may affect the expression and level of AOX4, such as air pollution and pollutants in food.
People with diabetes often have oxidative stress, and AOX4 levels may be elevated.
Enzyme linked immunosorbent assay (ELISA) is currently available to detect AOX4.
AOX4 can be used as one of the indicators to evaluate the antioxidant capacity in the body, reflecting the level of antioxidant capacity in the body to a certain extent.
AOX4 is a biomarker that reflects oxidative stress and oxidative protein damage, which is different from other biomarkers such as blood sugar and cholesterol.
Changes in AOX4 may be related to the occurrence and development of a variety of diseases, such as cardiovascular disease, chronic obstructive pulmonary disease, diabetes, cancer, etc. Therefore, the detection of AOX4 helps in the early detection and treatment of the disease.
AOX4 is mainly synthesized by the liver, and serum insulin-like growth factor (IGF) and albumin may also be a source of AOX4.
The AOX4 detection method is based on enzyme-linked immunosorbent assay (ELISA) to detect AOX4 levels, which is a non-invasive method.
AOX4 is a serum protein biomarker whose primary function is to assess the degree of oxidative stress in the body and the degree of oxidative damage to proteins.
AOX4 can be used as an auxiliary test indicator to help doctors better assess the patient's condition and treatment effect.
AOX4 is closely related to cardiovascular disease, chronic obstructive pulmonary disease, diabetes, cancer and other diseases.
Cancer patients have increased levels of oxidative stress, so AOX4 levels may also be elevated.
The accuracy of the AOX4 test depends on the test method and the quality of the kit, and there is currently no standardized AOX4 test.
AOX4 levels may be affected by lifestyle, such as smoking, drinking, exercise, etc., and can therefore be used to assess the impact of lifestyle.
Customer Reviews (4)
Write a reviewReproducibility was excellent and allowed me to evaluate the results more accurately.
The band clarity in Western blot is very high, which improves the reliability of the experiment.
AOX4 has a wide range of applications and adaptability.
The stability of this protein is impressive.
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