ap4b1
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  • Official Full Name
  • adaptor-related protein complex 4, beta 1 subunit
  • Background
  • The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243).
  • Synonyms
  • AP4B1; adaptor-related protein complex 4, beta 1 subunit; AP-4 complex subunit beta-1; beta 4 subunit of AP 4; BETA 4; Adapter related protein complex 4 beta 1 subunit; AP 4 adapter complex subunit beta; AP 4 complex subunit beta 1; Beta subunit of AP 4; beta4-adaptin; OTTHUMP00000013725; OTTHUMP00000013726; OTTHUMP00000013730; beta subunit of AP-4; beta 4 subunit of AP-4; AP-4 adapter complex subunit beta; adapter-related protein complex 4 subunit beta-1; CPSQ5; BETA-4
Cat.#:AP4B1-661HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human AP4B1 protein, GST-tagged
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Cat.#:AP4B1-9725HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human AP4B1, GST-tagged
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Cat.#:AP4B1-2606CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken AP4B1
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Cat.#:AP4B1-10662ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish AP4B1
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Cat.#:AP4B1-8806HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human AP4B1 293 Cell Lysate
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Involved Pathway

AP4B1 involved in several pathways and played different roles in them. We selected most pathways AP4B1 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Clathrin derived vesicle budding
APPB; AP1G1; TGOLN2; PPIAL4A; AP1B1; AP1M2; PICALM; NAPAB; CLINT1; DNM2
Golgi Associated Vesicle Biogenesis
AP1S1; HIP1RB; SNX9A; NECAP1; BLOC1S3; SNX9; SNAPIN; GAK; TFR1B; SNX9B
Lysosome
SORT1; SLC11A2; TCIRG1; SORT1B; AP3M2; PSAP; GALNS; ATP6AP1; AP3S2; ATP6V0B
Lysosome Vesicle Biogenesis
DNASE2; BLOC1S1; AP1S3A; CTSZ; CLVS2; CLVS1; AP4B1
Membrane Trafficking
SNX9A; TFR1B; RALAB; GJB4; COPG; GJD3; TCEAL4; GJA4; SEC22A; AP4B1
Vesicle-mediated transport
RALAA; PPP6R1; GJA4; SNF8; SNX9; NECAP1; SCGB3A2; HIP1RB; YIPF6; TRAPPC6A
trans-Golgi Network Vesicle Budding
CLVS1; NECAP1; TPD52L1; SNX9B; CNO; GAK; DNASE2; BLOC1S1; SNAPIN; TBC1D8B

Protein Function

AP4B1 has several biochemical functions, for example, protein binding, protein transporter activity, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP4B1 itself. We selected most functions AP4B1 had, and list some proteins which have the same functions with AP4B1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein NTRK3; CUL4B; AKT2; EPC1; ETNK1; LGALS9C; MB21D2; MYBPC1; TJAP1; ARHGDIA
Function protein transporter activity
Related Protein VPS26BL; IPO8; KPNA5; C11orf73; AP1S3A; L7RN6; ITGB1BP1; KPNA1; DSCR3; RANGRF
Function transporter activity
Related Protein LCN15; SYPL2A; AQP9B; SLC15A2; CRABP1A; SLC13A2; MIPB; AQP3B; SYP; FABP2

Interacting Protein

AP4B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4B1.
ZNF576; FIBP; MYC; AP4E1; AP4S1