|Official Full Name||adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1|
|Background||APPL1 (adaptor protein containing PH domain, PTB domain and leucine zipper motif 1) mediates adiponectin signaling in various types of cells. APPL1 is also thought to have a role in insulin signaling.|
|Synonyms||APPL1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; DCC-interacting protein 13-alpha; APPL; dip13-alpha; AKT2 interactor; signaling adaptor protein DIP13alpha; adapter protein containing PH domain, PTB domain an|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
APPL1 involved in several pathways and played different roles in them. We selected most pathways APPL1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with APPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Pathways in cancer||EGLN1; FGFR1; Kitl; AHA-1; AGTR1B; BDKRB1; PLCB2; BIRC2; TRAF1; GNG12|
|Colorectal cancer||AXIN1; PIK3CA; RAC2; AKT2; TRP53; MSH2; SMAD4; ARAF; BRAF; PIK3R1|
APPL1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by APPL1 itself. We selected most functions APPL1 had, and list some proteins which have the same functions with APPL1. You can find most of the proteins on our site.
|identical protein binding||THBS1; CNTN2; DNM1; NEFL; DVL2; HSPB1; COL2A1; YWHAZ; APOH; ITGA2B|
|protein binding||CDK5; SUV39H1; SLBP; CRIPT; SNTA1; MYCBP2; CACNG1; FAT4; BIRC3; DPP3|
|protein kinase B binding||PDE3B; PINK1; BAD; CDC37; RARA; APPL1; ANKRD2; BCL10; CCDC88A; TRAF6|
APPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of APPL1.