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Official Full Name adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Background APPL1 (adaptor protein containing PH domain, PTB domain and leucine zipper motif 1) mediates adiponectin signaling in various types of cells. APPL1 is also thought to have a role in insulin signaling.
Synonyms APPL1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; DCC-interacting protein 13-alpha; APPL; dip13-alpha; AKT2 interactor; signaling adaptor protein DIP13alpha; adapter protein containing PH domain, PTB domain an
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human APPL1-1001H Recombinant Human APPL1, His-tagged E.coli His
    Human APPL1-16H Recombinant Human APPL1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human APPL1-26345TH Recombinant Human APPL1, His-tagged E.coli His
    Human APPL1-725H Recombinant Human APPL1 protein, GST-tagged Wheat Germ GST
    Human APPL1-7563H Recombinant Human APPL1 Protein, His-tagged E.coli His
    Human APPL1-8772HCL Recombinant Human APPL1 293 Cell Lysate HEK293 N/A
    Human APPL1-9774H Recombinant Human APPL1, GST-tagged E.coli GST
    Human APPL-724H Recombinant Human APPL protein, GST-tagged Wheat Germ GST
    Mouse APPL1-1814M Recombinant Mouse APPL1 Protein Mammalian Cell His
    Zebrafish APPL1-6802Z Recombinant Zebrafish APPL1 Mammalian Cell His

    APPL1 involved in several pathways and played different roles in them. We selected most pathways APPL1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with APPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pathways in cancer EGLN1; FGFR1; Kitl; AHA-1; AGTR1B; BDKRB1; PLCB2; BIRC2; TRAF1; GNG12
    Colorectal cancer AXIN1; PIK3CA; RAC2; AKT2; TRP53; MSH2; SMAD4; ARAF; BRAF; PIK3R1

    APPL1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by APPL1 itself. We selected most functions APPL1 had, and list some proteins which have the same functions with APPL1. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding THBS1; CNTN2; DNM1; NEFL; DVL2; HSPB1; COL2A1; YWHAZ; APOH; ITGA2B
    protein binding CDK5; SUV39H1; SLBP; CRIPT; SNTA1; MYCBP2; CACNG1; FAT4; BIRC3; DPP3
    protein kinase B binding PDE3B; PINK1; BAD; CDC37; RARA; APPL1; ANKRD2; BCL10; CCDC88A; TRAF6

    APPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of APPL1.

    APPL2; RAB5A

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