ARMCX3 Protein, armadillo repeat containing, X-linked 3


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Official Full Name armadillo repeat containing, X-linked 3
Background This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.
Synonyms ARMCX3; armadillo repeat containing, X-linked 3; armadillo repeat-containing X-linked protein 3; ALEX3; 1200004E24Rik; ARM protein lost in epithelial cancers on chromosome X 3; Arm protein lost in epithelial cancers, X chromosome, 3; Armadillo repeat containing X linked protein 3; dJ545K15.2; DKFZp781N1954; KIAA0443; MGC12199
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARMCX3-835H Recombinant Human ARMCX3 protein, GST-tagged Wheat Germ GST
    Human ARMCX3-8694HCL Recombinant Human ARMCX3 293 Cell Lysate HEK293 N/A
    Mouse ARMCX3-1957M Recombinant Mouse ARMCX3 Protein Mammalian Cell His
    Rat ARMCX3-792R Recombinant Rat ARMCX3 Protein Mammalian Cell His
    Rhesus Macaque ARMCX3-412R Recombinant Rhesus monkey ARMCX3 Protein, His-tagged Mammalian Cell His

    ARMCX3 involved in several pathways and played different roles in them. We selected most pathways ARMCX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARMCX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ARMCX3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARMCX3 itself. We selected most functions ARMCX3 had, and list some proteins which have the same functions with ARMCX3. You can find most of the proteins on our site.

    Function Related Protein

    ARMCX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARMCX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARMCX3.


    Serrat, R; Lopez-Domenech, G; et al. The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3. PLOS ONE 8:-(2013).
    Lopez-Domenech, G; Serrat, R; et al. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. NATURE COMMUNICATIONS 3:-(2012).
    Mou, ZM; Tapper, AR; et al. The Armadillo Repeat-containing Protein, ARMCX3, Physically and Functionally Interacts with the Developmental Regulatory Factor Sox10. JOURNAL OF BIOLOGICAL CHEMISTRY 284:13629-13640(2009).

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