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ARMCX3

  • Official Full Name

    armadillo repeat containing, X-linked 3

  • Overview

    This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene.
  • Synonyms

    ARMCX3; armadillo repeat containing, X-linked 3; armadillo repeat-containing X-linked protein 3; ALEX3; 1200004E24Rik; ARM protein lost in epithelial cancers on chromosome X 3; Arm protein lost in epithelial cancers, X chromosome, 3; Armadillo repeat containing X linked protein 3; dJ545K15.2; DKFZp781N1954; KIAA0443; MGC12199;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ARMCX3-835H Recombinant Human ARMCX3 protein, GST-tagged Wheat Germ GST
Human ARMCX3-8694HCL Recombinant Human ARMCX3 293 Cell Lysate HEK293 N/A
Human ARMCX3-1289HF Recombinant Full Length Human ARMCX3 Protein, GST-tagged In Vitro Cell Free System GST 379 amino acids
Mouse ARMCX3-1957M Recombinant Mouse ARMCX3 Protein Mammalian Cell His
Mouse ARMCX3-741M-B Recombinant Mouse ARMCX3 Protein Pre-coupled Magnetic Beads HEK293
Mouse ARMCX3-741M Recombinant Mouse ARMCX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ARMCX3-792R Recombinant Rat ARMCX3 Protein Mammalian Cell His
Rat ARMCX3-448R Recombinant Rat ARMCX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ARMCX3-448R-B Recombinant Rat ARMCX3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ARMCX3-412R Recombinant Rhesus monkey ARMCX3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ARMCX3-241R Recombinant Rhesus Macaque ARMCX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ARMCX3-241R-B Recombinant Rhesus Macaque ARMCX3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ARMCX3 Related Articles

ARMCX3 involved in several pathways and played different roles in them. We selected most pathways ARMCX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARMCX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

ARMCX3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARMCX3 itself. We selected most functions ARMCX3 had, and list some proteins which have the same functions with ARMCX3. You can find most of the proteins on our site.

Function Related Protein

ARMCX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARMCX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARMCX3.

MAF1; CSNK2A1; CLTC; IMMT

Serrat, R; Lopez-Domenech, G; et al. The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3. PLOS ONE 8:-(2013).
Lopez-Domenech, G; Serrat, R; et al. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. NATURE COMMUNICATIONS 3:-(2012).
Mou, ZM; Tapper, AR; et al. The Armadillo Repeat-containing Protein, ARMCX3, Physically and Functionally Interacts with the Developmental Regulatory Factor Sox10. JOURNAL OF BIOLOGICAL CHEMISTRY 284:13629-13640(2009).
  • Q&As
  • Reviews

Q&As (8)

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Is the expression of the ARMCX3 gene regulated in a tissue-specific manner? 01/29/2022

Limited information is available regarding tissue-specific regulation of the ARMCX3 gene. Further studies are required to determine if the expression of ARMCX3 is regulated in a specific manner in different tissues.

Is ARMCX3 expression regulated by any specific transcription factors or signaling pathways? 01/16/2022

The regulatory mechanisms controlling ARMCX3 expression remain largely unknown. Future research can explore potential transcription factors or signaling pathways that may be involved in the regulation of ARMCX3 expression.

Has ARMCX3 been implicated in any specific diseases or conditions? 01/14/2022

As of now, there is limited evidence implicating ARMCX3 in specific diseases or conditions. However, with further research, it is possible that associations between ARMCX3 and particular diseases may emerge.

Is ARMCX3 expression restricted to certain cell types within the tissues where it is expressed? 12/06/2020

The cell-type-specific expression of ARMCX3 within its various tissue locations has not been thoroughly characterized. Further investigations are needed to determine the cellular distribution and expression patterns of ARMCX3.

Are there any animal models available for studying the function of ARMCX3? 09/23/2020

Currently, there are no known animal models specifically designed to study the function of ARMCX3. Generating animal models, such as knockout mice, could provide valuable insights into its biological roles in vivo.

Does the ARMCX3 protein play a role in any specific cellular processes or signaling pathways? 09/20/2020

The specific cellular processes or signaling pathways in which the ARMCX3 protein participates are not well-defined. Understanding its involvement in cellular processes and signaling pathways requires further investigation.

Are there any known genetic variations or mutations in the ARMCX3 gene associated with diseases? 06/02/2019

There is currently no strong evidence implicating genetic variations or mutations in the ARMCX3 gene in any specific diseases. However, more research is needed to explore potential links between ARMCX3 gene variations and disease susceptibility.

Are there any known interacting partners of the ARMCX3 protein? 04/01/2019

The ARMCX3 protein's interacting partners are not extensively characterized. Identifying and studying its protein-protein interactions are important areas for future research to uncover its functional network.

Customer Reviews (6)

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Reviews
04/14/2023

    Their dedicated team of experts is prompt, knowledgeable, and readily available to tackle any hurdles or concerns I may encounter.

    03/20/2020

      ARMCX3 protein is highly recommended for researchers due to its excellent performance in WB experiments and its utility in protein electron microscopy structure analysis.

      01/02/2020

        Its reliability and versatility make it an essential tool for investigating ARMCX3 protein's expression, function, and structural characteristics.

        12/03/2019

          With their expertise, I can navigate through experimental hurdles, optimize protocols, and ensure the seamless integration of the ARMCX3 protein into my investigations.

          11/11/2019

            The ARMCX3 protein showcases unparalleled quality, ensuring it surpasses expectations and satisfactorily addresses my experimental requirements.

            06/25/2019

              By visualizing the structural features, interactions, and conformational changes of ARMCX3, researchers gain valuable insights into its function and potential for therapeutic interventions.

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