ARRDC1
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Official Full Name
arrestin domain containing 1
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Synonyms
ARRDC1;arrestin domain containing 1;28633;ENSG00000197070;RP11-48C7.5;9q34.3;MGC40555;arrestin domain-containing protein 1;arrestin domain-containing protein 1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- ARRDC1 Related Articles
ARRDC1 involved in several pathways and played different roles in them. We selected most pathways ARRDC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ARRDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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ARRDC1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARRDC1 itself. We selected most functions ARRDC1 had, and list some proteins which have the same functions with ARRDC1. You can find most of the proteins on our site.
Function | Related Protein |
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ARRDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARRDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARRDC1.
UBE2E1; UBE2E3
- Q&As
- Reviews
Q&As (7)
Ask a questionModulating the activity of ARRDC1 or its interaction with receptors could be a potential therapeutic strategy for cardiovascular diseases. By targeting ARRDC1, it may be possible to attenuate cardiac hypertrophy and prevent the progression of heart failure. However, further research is needed to fully understand the underlying mechanisms and determine the feasibility and efficacy of targeting ARRDC1 in the treatment of cardiovascular diseases.
Currently, there are no specific drugs or therapeutic agents that directly target ARRDC1. However, understanding the functional significance of ARRDC1 in disease processes may guide the development of novel therapeutic strategies in the future. Modulating ARRDC1 activity or its interaction with specific receptors could have therapeutic benefits in diseases where ARRDC1 dysregulation plays a role.
ARRDC1 can regulate receptor signaling through multiple mechanisms. It can directly bind to receptors and promote their internalization, leading to receptor desensitization. ARRDC1 can also recruit other proteins involved in receptor signaling pathways, thereby influencing downstream signaling events. Additionally, ARRDC1 has been shown to regulate the levels and stability of certain receptors by promoting their ubiquitination and targeting them for degradation.
ARRDC1 has been found to interact with a variety of receptors, including beta-adrenergic receptors, angiotensin receptors, platelet-derived growth factor receptors, and epidermal growth factor receptors. These interactions are important for the regulation of receptor signaling and downstream cellular responses.
There is emerging evidence to suggest that ARRDC1 dysregulation may be associated with various diseases and conditions. For example, altered expression levels of ARRDC1 have been observed in certain types of cancer, including lung and breast cancer. Furthermore, aberrant ARRDC1 signaling has been implicated in cardiac hypertrophy and heart failure.
Yes, ARRDC1 is evolutionarily conserved across different species, including humans, mice, rats, and other organisms. This conservation suggests its importance in fundamental cellular processes and indicates potential functional significance across different organisms.
The expression of ARRDC1 can be regulated at both transcriptional and post-transcriptional levels. It has been reported that certain signaling pathways, such as the β-adrenergic signaling pathway, can upregulate ARRDC1 expression. Additionally, microRNAs have been identified that can bind to the ARRDC1 mRNA and regulate its stability, leading to changes in protein expression.
Customer Reviews (3)
Write a reviewI am confident that utilizing the ARRDC1 protein will empower me to uncover crucial insights into cellular mechanisms with precision.
The ARRDC1 protein is an exceptional protein solution that exceeds expectations in terms of quality and suitability for my experimental requirements.
Their expertise and guidance will undoubtedly prove valuable in overcoming hurdles and maximizing the potential of this protein in my research endeavors.
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