asb3
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  • Official Full Name
  • ankyrin repeat and SOCS box containing 3
  • Background
  • The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.
  • Synonyms
  • ASB3; ankyrin repeat and SOCS box containing 3; ankyrin repeat and SOCS box protein 3; ASB 3; Ankyrin repeat and SOCS box containing protein 3; ASB-3; ASB3_HUMAN; FLJ10123; FLJ10421; MGC12531; MGC132002; MGC996; Weakly similar to ankyrin brain variant 2
Cat.#:ASB3-1522HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ASB3, T7-tagged
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Cat.#:ASB3-26423THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ASB3, T7 -tagged
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Cat.#:ASB3-892HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ASB3 protein, GST-tagged
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Cat.#:ASB3-2015MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ASB3 Protein
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Cat.#:ASB3-316CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus ASB3 Protein, His-tagged
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Cat.#:ASB3-3162CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ASB3
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Cat.#:ASB3-10247ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ASB3
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Cat.#:ASB3-8664HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ASB3 293 Cell Lysate
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Cat.#:ASB3-8665HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ASB3 293 Cell Lysate
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Involved Pathway

ASB3 involved in several pathways and played different roles in them. We selected most pathways ASB3 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
OSBPL1A; NRG3; KLHL21; DYNC1LI2; LILRA1; TREML2; CTSL2; SRMS; IGKV1-5; MAP3K8
Antigen processing: Ubiquitination &
LRR1; ASB10; HECTD3; BLMH; ARIH2; UFL1; UBR2; LRRC41; ASB18; RNF144B
Proteasome degradation
DZIP3; ASB14; TRIM50; ASB18; RNF182; RNF144B; TRIM11; RNF19B; LTN1; RNF34
Class I MHC mediated antigen processing &
FBXO3; UFL1; LRR1; SEC61B; RNF41; ASB9; DTX3L; RBCK1; ASB18; UBE2U
presentation
SPSB4; ASB18; TRIM39; UBE2V2; CYBB; UFL1; ASB13; LRSAM1; TRIM11; SEC24A
Immune System
ABI1A; ISG20; ARIH1L; CASP4; MGC174152; TRIM50; TCIRG1; CASPBL; EIF4G2; ASB3

Protein Function

ASB3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB3 itself. We selected most functions ASB3 had, and list some proteins which have the same functions with ASB3. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein RNH1; RNF135; IPO11; CXCL2; ADIPOQ; SERTAD3; CPEB3; GTF2H4; PLP2; EXOC3

Interacting Protein

ASB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB3.
SH2D2A; HSP90AB1; KDM1A; ZAP70; TNS2; RIN3; eno; PRMT6