|Official Full Name||ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D|
|Background||This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c, c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes the V1 domain D subunit protein.|
|Synonyms||ATP6V1D; ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; ATP6M, ATPase, H+ transporting, lysosomal (vacuolar proton pump); V-type proton ATPase subunit D; VATD; VMA8; V-ATPase D subunit; V-ATPase subunit D; vacuolar H-ATPase subunit D; vacuolar p|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ATP6V1D involved in several pathways and played different roles in them. We selected most pathways ATP6V1D participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Oxidative phosphorylation||NDUFA13; NDUFS8; PPA1A; ATP5F1; NDUFA12; SDHDA; NDUFC1; COX17; NDUFB1; PPA1B|
|Metabolic pathways||MTMR8; PRPS2; aLA; AGXTA; PYGB; FUT3; B3GALNT1; ALPI.2; EPHX2; B3GALT5|
|Phagosome||TUBA3D; ITGB3; HLA-B; Ctsl; NCF2; CTSL1B; MHC2DCB; ATP6V1C1; TUBB; FCAR|
|Synaptic vesicle cycle||ATP6V0E2; STX1B; ATP6V1E2; SLC17A7; ATP6V1E1; SLC18A1; CPLX4; NSF; ATP6V1C1; NAPA|
|Collecting duct acid secretion||SLC12A7; ATP6V1E1; CA2; CLCNKB; ATP6V1A; ATP6V1B1; ATP6V0E; ATP6V0A2; ATP6V1D; SLC4A1|
|Vibrio cholerae infection||ATP6V0D1; GNAS; MUC2; ACTG1; ATP6V1E1; KDELR1; ATP6V0E1; ATP6V0A4; PRKACB; SEC61G|
|Epithelial cell signaling in Helicobacter pylori infection||CCL5; ATP6V1C1; RAC1; IKBKB; ATP6V1G1; IKBKG; ATP6V1B1; MAPK11; JAM3; MAPK12|
|Rheumatoid arthritis||VEGFA; TNFSF11; HLA-DPA1; ATP6V0A4; ATP6V0C; ATP6V1B2; ATP6V0E2; ANGPT1; IL17A; CCL2|
ATP6V1D has several biochemical functions, for example, ATPase activity, coupled to transmembrane movement of substances, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V1D itself. We selected most functions ATP6V1D had, and list some proteins which have the same functions with ATP6V1D. You can find most of the proteins on our site.
|ATPase activity, coupled to transmembrane movement of substances||ABCB6; ABCC3; ABCA1B; ABCG3; ABCA6; ATP6V1D; ABCC8; ABCB7; ABCC1; ABCC5|
|protein binding||GPSM2; FAM133A; DPYSL3; NFYB; CDAN1; TRIM29; KRT38; PRCP; CDK8; UTF1|
ATP6V1D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V1D here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V1D.
VPS52; NR2F6; SMAD2; RRAGB; pi3p; MYC; MYH7; ATP6V1A; PSMC1; PPP2CA; CLTC; USP7; Tmed10; GOLT1B