C1GALT1C1 Protein, C1GALT1-specific chaperone 1

C1GALT1C1

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C1GALT1C1

Official Full Name C1GALT1-specific chaperone 1
Background This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.
Synonyms C1GALT1C1; C1GALT1-specific chaperone 1; C1GALT2; COSMC; HSPC067; MGC19947; Beta 1,3 galactosyltransferase 2; Beta1,3 galactosyltransferase 2; C1Gal T2; C1GALT1 specific chaperone 1; C38H2 L1; C38H2 like protein 1; C38H2L1; Core 1 beta3 galactosyltransferase specific molecular chaperone; Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1,3 galactosyltransferase 2; MST143; C1Gal-T2; core 1 beta3-Gal-T2; C38H2-like protein 1; beta 1,3-galactosyltransferase 2; core 1 beta1,3-galactosyltransferase 2; core 1 beta3-galactosyltransferase-specific molecular chaperone; C38H2-L1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human C1GALT1C1-8191HCL Recombinant Human C1GALT1C1 293 Cell Lysate HEK293 N/A
    Mouse C1GALT1C1-2559M Recombinant Mouse C1GALT1C1 Protein Mammalian Cell His
    Rat C1GALT1C1-1040R Recombinant Rat C1GALT1C1 Protein Mammalian Cell His
    Rhesus Macaque C1GALT1C1-585R Recombinant Rhesus monkey C1GALT1C1 Protein, His-tagged Mammalian Cell His
    Chicken C1GALT1C1-5148C Recombinant Chicken C1GALT1C1 Mammalian Cell His
    Zebrafish C1GALT1C1-10066Z Recombinant Zebrafish C1GALT1C1 Mammalian Cell His

    C1GALT1C1 involved in several pathways and played different roles in them. We selected most pathways C1GALT1C1 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1GALT1C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mucin type O-Glycan biosynthesis GALNTL2; GCNT3; GALNTL1; GALNT14; GALNT18A; GCNT4; GALNT4; B3GNT6; GALNT18; GALNTL4
    Metabolic pathways GAA; ATP5G3; MT-ATP6; PFKMA; POLE; HK2; GALNT13; CDO1; PCYT1A; NOS2

    C1GALT1C1 has several biochemical functions, for example, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity, polypeptide N-acetylgalactosaminyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C1GALT1C1 itself. We selected most functions C1GALT1C1 had, and list some proteins which have the same functions with C1GALT1C1. You can find most of the proteins on our site.

    Function Related Protein
    glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity C1GALT1A; C1GALT1B; C1GALT1; C1GALT1C1
    polypeptide N-acetylgalactosaminyltransferase activity GALNT13; WBSCR17; GALNT6; GALNTL6; GALNT9; GALNTL4; GALNTL1; GALNT1; GALNT14; C1GALT1C1
    protein binding PLGRKT; PHYHD1; TMEM19; NEUROG1; SCO1; CPEB3; STARD3; ITM2C; AMPD2; C1GALT1C1

    C1GALT1C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1GALT1C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of C1GALT1C1.

    C1GALT1; ymfN; RNF41

    Chang, D; Gao, F; et al. Accounting for eXentricities: Analysis of the X Chromosome in GWAS Reveals X-Linked Genes Implicated in Autoimmune Diseases. PLOS ONE 9:-(2014).
    He, LY; Peng, YM; et al. Activation of the Interleukin-4/Signal Transducer and Activator of Transcription 6 Signaling Pathway and Homeodomain-Interacting Protein Kinase 2 Production by Tonsillar Mononuclear Cells in IgA Nephropathy. AMERICAN JOURNAL OF NEPHROLOGY 38:321-332(2013).

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