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Official Full Name calcium/calmodulin-dependent protein kinase IV
Background The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
Synonyms CAMK4; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase type IV; brain Ca++ calmodulin dependent protein kinase type IV; calcium/calmodulin dependent protein kinase type IV catalytic chain; CAM kinase IV; CAM kin
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat CAMK4-379R Recombinant Rat CAMK4 Protein (1-474 aa), His-tagged E.coli His
    Human CAMK4-0336H Recombinant Human CAMK4 Protein, GST-Tagged Wheat Germ GST
    Human CAMK4-1373H Recombinant Human CAMK4 (Active), GST-tagged Sf9 Insect Cell GST
    Human CAMK4-1379H Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase IV, His-tagged E.coli His
    Human CAMK4-2493H Recombinant Human CAMK4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CAMK4-26208TH Recombinant Human CAMK4 N/A
    Human CAMK4-268H Recombinant Human CAMK4, GST-tagged, Active Sf9 Insect Cell GST
    Human CAMK4-956H Recombinant Human CAMK4, GST tagged Insect Cell GST
    Mouse CAMK4-001MCL Recombinant Mouse CAMK4 cell lysate Insect Cell N/A
    Mouse Camk4-477M Recombinant Mouse Camk4, Gly & Pro tagged Insect Cell His
    Mouse Camk4-7403M Recombinant Mouse Camk4, His & GST tagged Insect Cell His/GST
    Rat CAMK4-1106R Recombinant Rat CAMK4 Protein Mammalian Cell His
    Chicken CAMK4-3271C Recombinant Chicken CAMK4 Mammalian Cell His
    Zebrafish CAMK4-2379Z Recombinant Zebrafish CAMK4 Mammalian Cell His

    CAMK4 involved in several pathways and played different roles in them. We selected most pathways CAMK4 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling pathway CAMK4; ADCY2B; SLC8A4A; LTB4R2; CHRM2; EDNRA; EDNRB; CALM2A; ADORA2AA; SPHK1
    cAMP signaling pathway GNAI3; CNGA1; PPARA; HCN4; ORAI1; RAP1A; GLI3; PIK3CD; ATP2B1; ATP1A2
    Osteoclast differentiation SIRPA; CYLD; MAP3K14; IKBKG; FOSL2; MAPK12; FCGR1A; PIK3CD; PPARG; MAPK3
    Long-term potentiation RPS6KA1; ARAF; ATF4; GRM1; PRKACA; RPS6KA2; GNAQ; RPS6KA6; ITPR1; GRIN2A
    Neurotrophin signaling pathway TRAF6; NGF; MAP3K5; RPS6KA5; SORT1; RAC1; CAMK4; AKT1; CALML3; CDC42
    Cholinergic synapse PIK3CD; KCNQ3; CREB3; CAMK2A; KCNQ2; CHRNA6; CHAT; GNGT2; ACHE; GNAO1
    Oxytocin signaling pathway PRKCB; PRKACG; PTGS2; SRC; CALM3; PRKAG3; PLA2G4A; GNAS; PPP1R12A; CAMKK1
    Aldosterone synthesis and secretion MC2R; DAGLB; ADCY8; KCNK9; PLCB3; ATF2; PRKCE; CAMK1D; CREB5; ITPR3
    Amphetamine addiction GRIA4; GRIN1; GRIN3B; ATF6B; CAMK2G; CREB3L3; JUN; CALML3; CALM2; GRIA1

    CAMK4 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK4 itself. We selected most functions CAMK4 had, and list some proteins which have the same functions with CAMK4. You can find most of the proteins on our site.

    Function Related Protein
    calcium-dependent protein serine/threonine kinase activity MKNK2A; MAPKAPK5; CAMK1GB; MKNK1; CAMK4; MAPKAPK2B; DCX; MKNK2; MAPKAPK2; MAPKAPK2A
    calmodulin binding CASK; KCNN1B; USP6; PPP3CC; ATP2B4; SPTAN1; PPP3CA; TJP1; KCNN3; MYO1A
    calmodulin-dependent protein kinase activity CAMK1D; MKNK2A; SLC14A2; MKNK1; MAPKAPK2A; MAPKAPK2B; CAMK2A; PTK2B; CAMK1G; CAMK2D

    CAMK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK4.


    Sugiyama, Y; Murao, K; et al. Calcium/calmodulin-dependent protein kinase IV involvement in the pathophysiology of glucotoxicity in rat pancreatic beta-cells. METABOLISM-CLINICAL AND EXPERIMENTAL 60:145-153(2011).
    Blanquet, PR; Mariani, J; et al. Temporal assessment of histone H3 phospho-acetylation and casein kinase 2 activation in dentate gyms from ischemic rats. BRAIN RESEARCH 1302:10-20(2009).

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