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Official Full Name Cbl proto-oncogene, E3 ubiquitin protein ligase B
Background E3 ubiquitin-protein ligase CBL-B is an enzyme that in humans is encoded by the CBLB gene.
Synonyms CBLB; Cbl proto-oncogene, E3 ubiquitin protein ligase B; Cas Br M (murine) ecotropic retroviral transforming sequence b , Cas Br M (murine) ectropic retroviral transforming sequence b; E3 ubiquitin-protein ligase CBL-B; Cbl b; RNF56; RING finger protein
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • Avi
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CBLB-01H Recombinant Human CBLB Protein Insect cells
    Human CBLB-036H Recombinant Human CBLB Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Mouse Cblb-1974M Recombinant Mouse Cblb Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human CBLB-19H Recombinant Human CBLB Protein, His-Avi-tagged, Biotinylated E.coli His/Avi
    Human CBLB-733H Recombinant Human CBLB protein, His-tagged E.coli His
    Human CBLB-10756H Recombinant Human CBLB, His-tagged E.coli His
    Human CBLB-18H Recombinant Human CBLB, MYC/DDK-tagged HEK293 Myc/DDK
    Human CBLB-578H Recombinant Human CBLB, GST-tagged Wheat Germ GST
    Human CBLB-579H Recombinant Human CBLB, GST-tagged Wheat Germ GST
    Human CBLB-7814HCL Recombinant Human CBLB 293 Cell Lysate HEK293 N/A
    Rat CBLB-1155R Recombinant Rat CBLB Protein Mammalian Cell His

    CBLB involved in several pathways and played different roles in them. We selected most pathways CBLB participated on our site, such as ErbB signaling pathway, Ubiquitin mediated proteolysis, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBLB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway HRASB; PRKCBB; AKT3A; SHC2; PIK3CG; CDKN1BB; MAPK8; GRB2A; MYCB; MAPK3
    Ubiquitin mediated proteolysis UBE2NB; CUL1B; KEAP1B; UBE2F; RFWD2; UBE2D1; ANAPC11; SIAH1; NEDD4; KLHL13
    T cell receptor signaling pathway PDCD1; IKBKG; GRB2; IL5; PTPRC; MAPK9; MAP2K7; RELA; NFATC2; NFKBIA
    Insulin signaling pathway FLOT2; FLOT1; INSRB; HK3; HK2; IRS4; GYS2; PPP1R3B; FBP1A; PPP1R3CA
    Bacterial invasion of epithelial cells CLTC; SHC1; CRKL; WASL; ELMO2; CTTN; CAV2; SEPT9; PIK3CB; ACTB
    Measles cgr2b; PIK3R1; IL2RA; IFNA10; Fasl; CD209; CCNE1; IFNG; CBLB; TLR7
    Pathways in cancer FGF20; TRAF5; SLC2A1; F2RL3; GRB2; KIT; FGF21; RUNX1T1; TGFB2; GLI1
    Proteoglycans in cancer CAMK2B; PTK2; GPC1; ITGB3; MAPK13; GAB1; PTPN11; PXN; MTOR; PIK3R1
    Chronic myeloid leukemia SHC4; CDK6; NFKB1; CBLB; TGFB2; PIK3CG; MAPK3; CBLC; SMAD4; PIK3R1

    CBLB has several biochemical functions, for example, calcium ion binding, ligase activity, phosphotyrosine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBLB itself. We selected most functions CBLB had, and list some proteins which have the same functions with CBLB. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding CBLC; PVALB2; KCNIP3B; ADAM8; MMP8; BMP1A; MCTP2; S100A5; ANXA7; BGLAP2
    ligase activity UCHL1; LNX1; MYLIPB; GLULC; RNF40; UBE2G1A; RNF144B; RNF5; DTX2; TRIM2
    phosphotyrosine binding FGR; CBL; CBLC; LDLRAP1; ACP2; CBLB; MAPK3; GRB2; SAMSN1; ZAP70
    protein binding GZMB; ASXL1; MOS; HSPB8; AKAP12; CTLA2B; SEPT12; UTP23; PHF15; HPCAL1
    signal transducer activity TAAR14L; CRKL; HTR5AL; TAAR7F; RASGRP3; GNG12; CALCRLA; OLFCD2; ADRA2DB; ADCYAP1R1A
    ubiquitin-protein transferase activity UBE2Q2; TRIM5; MARCH1; RNF144AB; TRIP12; RNF43; BTR22; UBE2E3; UBE2E1; CBLB
    zinc ion binding TRIM63; DNAJC24; SEC24D; CA12; ACE; MANEA; BMP1B; MMP23B; RBM10; LIMS1

    CBLB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBLB here. Most of them are supplied by our site. Hope this information will be useful for your research of CBLB.


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