CDK11B Protein, cyclin-dependent kinase 11B


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Official Full Name cyclin-dependent kinase 11B
Background PITSLRE, alternatively known as cell division kinase 11 (CDK11), is the result of duplication of the CDK11 gene (1). CDK11A and CDK11B encode nearly identical serine/threonine protein kinases, PITSLREB and PITSLREA respectively, both belonging to the p34C
Synonyms CDK11B; cyclin-dependent kinase 11B; CDC2L1, cell division cycle 2 like 1 (PITSLRE proteins); CDK11 p46; CDK11 p58; CDK11 p110; PITSLREA; p58 CLK-1; CDC-related protein kinase p58; cell division protein kinase 11B; cell division cycle 2-like protein kina
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDK11B-127H Recombinant Human CDK11B, GST-tagged Sf9 Insect Cell GST
    Human CDK11B-5130H Recombinant Human CDK11B Protein, GST-tagged Wheat Germ GST
    Rat CDK11B-1300R Recombinant Rat CDK11B Protein Mammalian Cell His
    Zebrafish CDK11B-1932Z Recombinant Zebrafish CDK11B Mammalian Cell His

    CDK11B involved in several pathways and played different roles in them. We selected most pathways CDK11B participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Centrosome maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK11B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle MYBL2; PLK1; CEP164; CEP63; ARPP19; SGOL2; TUBGCP2; ITGB3BP; CEP72; TGFB1
    Centrosome maturation CDK11A; CEP135; PLK4; CEP76; CENPJ; CSNK1D; CSNK1E; CEP290; SSNA1; TSGA14
    G2/M Transition DCTN1; NDE1; MAPRE1; CKAP5; TSGA14; CEP78; MYBL2; CLASP1; NINL; CEP164
    Mitotic G2-G2/M phases FOXM1; BORA; TUBGCP5; NUMA1; TCTN2; TUBGCP4; LIN52; LIN9; CDK11B; TUBGCP3
    Recruitment of mitotic centrosome proteins and complexes TUBGCP4; TUBGCP2; TUBG2; NUMA1; TUBGCP3; CDK11A; TUBGCP5; CDK11B

    CDK11B has several biochemical functions, for example, ATP binding, cyclin-dependent protein serine/threonine kinase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK11B itself. We selected most functions CDK11B had, and list some proteins which have the same functions with CDK11B. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding NDUFA13; SHPRH; SPHK1; DDX24; P2RX3A; TOR1L1; DHX37; MYO1EB; CCT8; ATP2B3B
    cyclin-dependent protein serine/threonine kinase activity ICK; CCND3; CDK3; CDKL4; CDK11B; CDKL5; CDK14; MAK; CDK15; CDK10
    poly(A) RNA binding ALG13; EIF2C3; ZFML; YBX1; SNRNP40; NKAP; GTL3; SYF2; CAPRIN1; MRPL3
    protein binding MAB21L3; KRT6B; ARID3A; BLOC1S1; PRDM1; SIRPG; KANK2; C19orf46; VAMP2; ABCB1
    protein kinase activity IRAK1; EGFRA; TESK2; CAMKK1B; CCND1; PLK1; STK4; RAF1B; PPP1R9B; SLKA
    protein serine/threonine kinase activity STK32C; RPS6KB1B; MAPK6; MOK; BMPR1AA; NUAK2; GRK1B; AKT3A; PAK2A; ERN1

    CDK11B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK11B here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK11B.


    Kamal, A; Reddy, VS; et al. Synthesis of imidazo[2,1-b][1,3,4]thiadiazole-chalcones as apoptosis inducing anticancer agents. MEDCHEMCOMM 5:1718-1723(2014).
    Griffin, D; Liu, XF; et al. Expression of Progesterone Receptor Membrane Component-2 Within the Immature Rat Ovary and Its Role in Regulating Mitosis and Apoptosis of Spontaneously Immortalized Granulosa Cells. BIOLOGY OF REPRODUCTION 91:-(2014).

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