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CDK11B

Official Full Name

cyclin-dependent kinase 11B
Overview

PITSLRE, alternatively known as cell division kinase 11 (CDK11), is the result of duplication of the CDK11 gene (1). CDK11A and CDK11B encode nearly identical serine/threonine protein kinases, PITSLREB and PITSLREA respectively, both belonging to the p34C
Synonyms

CDK11B; cyclin-dependent kinase 11B; CDC2L1, cell division cycle 2 like 1 (PITSLRE proteins); CDK11 p46; CDK11 p58; CDK11 p110; PITSLREA; p58 CLK-1; CDC-related protein kinase p58; cell division protein kinase 11B; cell division cycle 2-like protein kina;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Sf9 Insect Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDK11B-127H	Recombinant Human CDK11B, GST-tagged	Sf9 Insect Cell	GST		Inquiry
Human	CDK11B-5130H	Recombinant Human CDK11B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CDK11B-723H	Recombinant Human CDK11B Protein, His-tagged	E.coli	N-His	Phe438-Arg724	Inquiry
Rat	CDK11B-1300R	Recombinant Rat CDK11B Protein	Mammalian Cell	His		Inquiry
Rat	CDK11B-958R	Recombinant Rat CDK11B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	CDK11B-958R-B	Recombinant Rat CDK11B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	CDK11B-1932Z	Recombinant Zebrafish CDK11B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CDK11B Related Articles

CDK11B involved in several pathways and played different roles in them. We selected most pathways CDK11B participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Centrosome maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK11B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	TGFB2;HIST4H4;PCNA;NEK9;CENPO;ENSAA;BUB1;SPC25;SETB
Cell Cycle, Mitotic	BLZF1;CEP72;DYNC1H1;CENPQ;SPC24;SETA;CTDNEP1;TUBG1;APITD1
Centrosome maturation	DCTN1A;CEP72;DYNC1H1;TUBGCP5;NEDD1;OFD1;ODF2;DCTN2;SDCCAG8
G2/M Transition	TUBGCP5;CKAP5;ODF2;CEP57;CP110;CEP72;BORA;LIN9;HAUS2
Mitotic G2-G2/M phases	FOXM1;TUBGCP3;BORA;LIN52;TUBGCP4;NUMA1;TUBG2;LIN9;CDK11A
Recruitment of mitotic centrosome proteins and complexes	TUBGCP2;CDK11A;TUBGCP4;NUMA1;TUBGCP3;TUBGCP5;TUBG2;CDK11B

CDK11B has several biochemical functions, for example, ATP binding, cyclin-dependent protein serine/threonine kinase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK11B itself. We selected most functions CDK11B had, and list some proteins which have the same functions with CDK11B. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	NEK11;SYN2B;P2RY1;MYH4;RIMKLA;CKM;MAT2AL;AURKB;FRK
cyclin-dependent protein serine/threonine kinase activity	CDKL1;CCNK;CDKL5;CDK14;CDK5R1;STK30;NAT1;CDK15;CDK7
poly(A) RNA binding	NOC2L;RRP12;EIF4A2;ZNF622;CSTF2T;KHDRBS3;DHX15;NOL12;HSD17B10
protein binding	CTNNBL1;BLOC1S5;HDDC2;CCDC85B;LASP1;COMMD2;PLAA;RCOR3;MED12
protein kinase activity	CAMKVB;CSF1RA;SBK3;GRK7B;CDK1;GM711;MAP3K10;PDK3;STK24B
protein serine/threonine kinase activity	LIMK1;CSNK1G3;GAK;ARAF;STK16;SYK;ADCK1;TNIK;SLK

CDK11B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK11B here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK11B.

KAT7; PAK1; EIF3F; RNPS1; TPPP; MSN; CCND3; RPS27A; AP2M1

Kamal, A; Reddy, VS; et al. Synthesis of imidazo[2,1-b][1,3,4]thiadiazole-chalcones as apoptosis inducing anticancer agents. MEDCHEMCOMM 5:1718-1723(2014).

Griffin, D; Liu, XF; et al. Expression of Progesterone Receptor Membrane Component-2 Within the Immature Rat Ovary and Its Role in Regulating Mitosis and Apoptosis of Spontaneously Immortalized Granulosa Cells. BIOLOGY OF REPRODUCTION 91:-(2014).