cdk14
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  • Official Full Name
  • cyclin-dependent kinase 14
  • Background
  • PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 (PubMed;11313143)).
  • Synonyms
  • CDK14; cyclin-dependent kinase 14; PFTAIRE protein kinase 1 , PFTK1; PFTAIRE1; hPFTAIRE1; PFTAIRE protein kinase 1; cell division protein kinase 14; serine/threonine-protein kinase PFTAIRE-1; PFTK1; KIAA0834
Cat.#:CDK14-3158HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDK14 Protein, MYC/DDK-tagged
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Cat.#:CDK14-116HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CDK14/CyclinY, GST-tagged
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Cat.#:CDK14-180HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CDK14, GST-tagged
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Cat.#:CDK14-3194MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CDK14 Protein
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Cat.#:CDK14-6824ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDK14
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Involved Pathway

CDK14 involved in several pathways and played different roles in them. We selected most pathways CDK14 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK14 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Transcriptional misregulation in cancer
ID2; LYL1; LDB1; ZEB1; RUNX1T1; H3F3B; TP53; ASPSCR1; HIST1H3F; RXRA

Protein Function

CDK14 has several biochemical functions, for example, ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK14 itself. We selected most functions CDK14 had, and list some proteins which have the same functions with CDK14. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ACSS3; PRPS1; DGKB; PANK2; ABCC5; ACTC1B; ZAK; CSF1R; ORC1L; MAP4K5
Function cyclin binding
Related Protein CDK13; PTCH1; FBXW7; CUL3; INCA1; CDK12; HDAC3; CDKN1A; MDFIC; CDK6
Function cyclin-dependent protein serine/threonine kinase activity
Related Protein CDK14; ICK; CDK5R1; CDK8; CDK1; CDKL3; STK30; MOK; CDK19; CDK4
Function kinase activity
Related Protein GSK3AB; NLK1; TNK2B; CSNK1G2A; PRKCBB; CSNK1G2B; BMPR2A; PTK2AB; MAPK12B; TLK1B
Function nucleotide binding
Related Protein ATAD5B; MAT2AB; SGK2A; RAB1; RMI1; TNK2B; SNRPB2; KIF4; NXF2; GMPPAB
Function protein kinase activity
Related Protein CCL3; SNRKB; IKBKB; POMK; DAPK1; MAK; CAMKK1B; CDK11A; RAF1; EIF2AK3
Function protein serine/threonine kinase activity
Related Protein CSNK1DB; HIPK1; SRPK2; ULK1A; ACVR2B; SMOK2B; ALPK2; MARK3; CDK5; EIF2AK2
Function transferase activity
Related Protein ACVR2AA; PKMB; CHST3B; GMPPAB; NTRK2B; PANK1A; TNIKA; SETD8A; PCMTL; UGT5F1

Interacting Protein

CDK14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK14.
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CDK14 Related Articles

Aoshiba, K; Tsuji, T; et al. Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 65:1053-1062(2013).
Capobianco, G; Marras, V; et al. P16 immunostaining and HPV testing in histological specimens from the uterine cervix. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 34:227-230(2013).