CDK14 Protein, cyclin-dependent kinase 14

CDK14

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CDK14

Official Full Name cyclin-dependent kinase 14
Background PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 (PubMed;11313143)).
Synonyms CDK14; cyclin-dependent kinase 14; PFTAIRE protein kinase 1 , PFTK1; PFTAIRE1; hPFTAIRE1; PFTAIRE protein kinase 1; cell division protein kinase 14; serine/threonine-protein kinase PFTAIRE-1; PFTK1; KIAA0834
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDK14-116H Recombinant Human CDK14/CyclinY, GST-tagged Sf9 Insect Cell GST
    Human CDK14-180H Recombinant Human CDK14, GST-tagged Sf9 Insect Cell GST
    Human CDK14-3158H Recombinant Human CDK14 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse CDK14-3194M Recombinant Mouse CDK14 Protein Mammalian Cell His
    Zebrafish CDK14-6824Z Recombinant Zebrafish CDK14 Mammalian Cell His

    CDK14 involved in several pathways and played different roles in them. We selected most pathways CDK14 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Transcriptional misregulation in cancer LRP2BP; CEBPE; TMPRSS2; ZBTB16; HIST1H3C; NR4A3; PPARG; BCL2A1; MYCN; FLT3

    CDK14 has several biochemical functions, for example, ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK14 itself. We selected most functions CDK14 had, and list some proteins which have the same functions with CDK14. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding CLCN5; ATP2A1; ACVR1; EPHA4A; ABCG4B; CERK; Aatk; DNAH11; ACOT12; MTPAP
    cyclin binding CUL3; FBXW7; CDK13; CDK5RAP3; CDKN1A; CDK14; USP2; HDAC3; PTCH1; CDK6
    cyclin-dependent protein serine/threonine kinase activity CDK5; CDK1; MOK; CDKL3; CDK11A; PFTK1; CDK5R1; ICK; CDK4; CDK13
    kinase activity EPHB3A; TRIO; MAPKAPK2A; STK35L; CAMK2N1A; PRKACAB; PPIP5K2; TNIKA; ACVR2AA; PRKAR2AB
    nucleotide binding G3BP2; RTCD1; GNAV1; SRSF10; NEK5; TUBA8L4; SRSF6A; CIRBP; DDX39; RBM12B1
    protein kinase activity PRKACBA; PTK2AA; RPS6KB2; FGFR1B; CDK8; EPHB2B; STK25B; AURKA; SLKA; PIK3C3
    protein serine/threonine kinase activity MAP2K5; RIOK1; SIK2A; ICK; PRKD2; PAK2; NEK9; MAP2K3; AKT1; PDPK1
    transferase activity UGT5A5; ETNPPL; SMOK2B; HHAT; GGTA1; SMYD2B; PNP4A; NLK1; UGT2B5; TLK1B

    CDK14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK14 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK14.

    Ccny

    Aoshiba, K; Tsuji, T; et al. Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 65:1053-1062(2013).
    Capobianco, G; Marras, V; et al. P16 immunostaining and HPV testing in histological specimens from the uterine cervix. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 34:227-230(2013).

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