cenpp
Share
  • Official Full Name
  • centromere protein P
  • Background
  • CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM;117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006;(PubMed 16622420)).
  • Synonyms
  • CENPP; centromere protein P; CENP P; RP11 19J3.3; FLJ33928; RP11-19J3.3; OTTHUMP00000021661; CENP-P
Cat.#:CENPP-1124HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CENPP Protein, GST-Tagged
+Inquiry
Cat.#:CENPP-2448HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant human CENPP, His-tagged
+Inquiry
Cat.#:CENPP-814RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CENPP Protein, His-tagged
+Inquiry
Cat.#:CENPP-3427CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CENPP
+Inquiry
Cat.#:CENPP-988ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CENPP
+Inquiry
Cat.#:CENPP-7577HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CENPP 293 Cell Lysate
+Inquiry

Involved Pathway

CENPP involved in several pathways and played different roles in them. We selected most pathways CENPP participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Chromosome Maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CENPP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
NEK9; E2F3; RAD9A; KIF2B; PCM1; SUN1; AURKB; RAD50; FZR1A; NPM1
Cell Cycle, Mitotic
ARPP19; CEP76; CP110; NUP50; KIF18A; NDEL1A; DPF1; TUBG2; TCTN2; PCM1
Chromosome Maintenance
NPM1; POLD3; MLF1IP; CENPW; SMARCA5; WRAP53; MIS18A; DNA2; CENPH; APITD1
Deposition of new CENPA-containing nucleosomes at the centromere
CENPW; MIS18BP1; MIS18A; ITGB3BP; CENPC1; MLF1IP; NPM1; PANE1; CENPK; CENPI
M Phase
KIF18A; SKA2; CENPP; NDEL1B; MIS12; GOLGA2; SKA1; NDEL1; NUDC; ARPP19B
Mitotic Anaphase
MLF1IP; ZWILCH; SPC24; ANKLE2; NDC80; ITGB3BP; CENPK; CENPH; CENPC1; CDCA8
Mitotic Metaphase and Anaphase
SGOL1; CENPP; NSL1; CDCA5; NUF2; ZWINT; MIS12; CENPQ; NDEL1; KNTC1
Mitotic Prometaphase
DSN1; PDS5B; NCAPH; RANGAP1B; MLF1IP; NCAPG; CENPI; SPDL1; PANE1; CDCA5

Protein Function

CENPP has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CENPP itself. We selected most functions CENPP had, and list some proteins which have the same functions with CENPP. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein SUMO3; DCTN2; SEPT7; ACVRL1; SMG9; TDGF1; CFH; GDI2; RNF115; ZCCHC8

Interacting Protein

CENPP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CENPP here. Most of them are supplied by our site. Hope this information will be useful for your research of CENPP.
CENPO; 80125; RPIA; GOLGA2; NHLH1; KLC3; TEX11

CENPP Related Articles

Mahler, M; Fritzler, MJ; et al. Autoantibodies to the mitochondrial RNA processing (MRP) complex also known as Th/To autoantigen. AUTOIMMUNITY REVIEWS 14:254-257(2015).
Mahler, M; Satoh, M; et al. Autoantibodies to the Rpp25 Component of the Th/To Complex are the Most Common Antibodies in Patients with Systemic Sclerosis without Antibodies Detectable by Widely Available Commercial Tests. JOURNAL OF RHEUMATOLOGY 41:1334-1343(2014).