COMMD1

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COMMD1

Official Full Name copper metabolism (Murr1) domain containing 1
Background COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al.,;2005 (PubMed 16267171)).
Synonyms COMMD1; copper metabolism (Murr1) domain containing 1; C2orf5, chromosome 2 open reading frame 5 (MURR1); COMM domain-containing protein 1; copper metabolism gene MURR1; MGC27155; MURR1; C2orf5; COMD1; COMD1_HUMAN; copper metabolism domain containing 1; Protein Murr1; OTTHUMP00000159817
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COMMD1-1674H Recombinant Human COMMD1 Protein, GST-tagged Wheat Germ GST
    Human COMMD1-2732H Recombinant Human COMMD1, His-tagged E.coli His
    Human COMMD1-28013TH Recombinant Human COMMD1, His-tagged E.coli His
    Human COMMD1-28014TH Recombinant Human COMMD1, His-tagged E.coli His
    Human COMMD1-7373HCL Recombinant Human COMMD1 293 Cell Lysate HEK293 N/A
    Zebrafish COMMD1-4265Z Recombinant Zebrafish COMMD1 Mammalian Cell His

    COMMD1 involved in several pathways and played different roles in them. We selected most pathways COMMD1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with COMMD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TNF-alpha/NF-kB Signaling Pathway KTN1; NKIRAS1; NKIRAS2; TNIP1; COPS3; LRPPRC; USP2; UNC5CL; G3BP2; KPNA6

    COMMD1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by COMMD1 itself. We selected most functions COMMD1 had, and list some proteins which have the same functions with COMMD1. You can find most of the proteins on our site.

    Function Related Protein
    copper ion binding SERPINB1A; LOX; S100U; P2RX2; CUTC; MT1; LOXL4; HAMP; CCS; POLR1B
    identical protein binding IK; RCAN1; ATL1; MYBPC3; CORO1B; HAND1; MUL1; ABCD1; VPS41; ADIPOR1
    phosphatidic acid binding COMMD1; JPH2; MICALL1; PLCD1; SESTD1; NRGN; MARK1; UQCC3; MAPKAP1; RAPGEF6
    phosphatidylinositol-3,4,5-trisphosphate binding BTK; RAG2; RACGAP1; ARAP1; DAPP1; GAB2; FAM21C; ANXA8; PIRT; ZFYVE1
    phosphatidylinositol-3,4-bisphosphate binding FAM21C; PHLDA3; NCF1; KIF16B; ANXA8; AKT1; COMMD1; TTPA; RAG2; RS1
    phosphatidylinositol-3,5-bisphosphate binding WIPI1; PHLDA3; CLVS1; FAM21C; SH3PXD2B; RS1; RAG2; WDR45L; MAPKAP1; JPH2
    phosphatidylinositol-4,5-bisphosphate binding VIL1; RAG2; ALOX15; STXBP6L; FAM123A; SYT1; PLCB1; ADAP2; COMMD1; TTPA
    protein binding TMEM203; UNC13B; CNST; RAPGEF6; BCR; PDXP; ZMYM4; SNX4; MIF; IMPA2
    protein homodimerization activity ATIC; MID2; NUDT16; ZBTB16; HMGCR; VPS4B; ACOT7; DMRTA2; MYOM1; PPP2R4

    COMMD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COMMD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COMMD1.

    COMMD6; CCDC22

    Phillips-Krawczak, CA; Singla, A; et al. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. MOLECULAR BIOLOGY OF THE CELL 26:91-103(2015).
    Li, HY; Burstein, E; et al. COMMD1 regulates inflammation and colitis-associated cancer progression. ONCOIMMUNOLOGY 3:-(2014).

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