|Official Full Name||coproporphyrinogen oxidase|
|Background||The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).|
|Synonyms||CPOX; coproporphyrinogen oxidase; coproporphyrinogen oxidase (coproporphyria, harderoporphyria) , CPO; coproporphyrinogen-III oxidase, mitochondrial; coproporphyria; CPX; HCP; COX; coprogen oxidase; coproporphyrinogenase; CPO|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CPOX involved in several pathways and played different roles in them. We selected most pathways CPOX participated on our site, such as Heme Biosynthesis, Metabolic pathways, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPOX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Heme Biosynthesis||COX15; COX10; CPOX|
|Metabolic pathways||GALNT18; FUT6; TBXAS1; AKR1B1L; MPI; ATP5F1; HSD17B6; IMPA2; MGAT1B; HIBADH|
|Metabolism||SCP2B; ACOT8; CYP24A1; EPM2A; CYP3A7; MED22; BRP44; CYP17A1; ACOT10; SLC25A16|
|Metabolism of porphyrins||UGT1B4; COX15; UGT1B3; UGT1B5; CPOX; UGT1B7; COX10; UGT1B1; UGT1B2|
|Porphyrin and chlorophyll metabolism||UGT2A2; UGT1A9; UGT1A7; MMAB; UGT1A3; FECH; UGT1A2; HMOX2A; EPRS; BLVRB|
|heme biosynthesis I (aerobic)||CPOX|
CPOX has several biochemical functions, for example, coproporphyrinogen oxidase activity, protein homodimerization activity, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by CPOX itself. We selected most functions CPOX had, and list some proteins which have the same functions with CPOX. You can find most of the proteins on our site.
|coproporphyrinogen oxidase activity||CPOX; RSAD1|
|protein homodimerization activity||ATPIF1; NKX2; NR6A1; TERF1; PVRL1A; GPD1C; TERT; DDX1; TIMELESS; AMICA1|
|structural constituent of eye lens||HSPB6; CRYBA4; LIM2.5; ASL1; BFSP1; CRYAA; BFSP2; MIP; CRYBB2; CRYGF|
CPOX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPOX here. Most of them are supplied by our site. Hope this information will be useful for your research of CPOX.
UBE2G2; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine; Fech; Cpox; Slc25a4; Ppox; Slc25a5; Vdac2; Abcb7; Glrx5; Slc25a11; Abcb10