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CPOX

  • Official Full Name

    coproporphyrinogen oxidase

  • Overview

    The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
  • Synonyms

    CPOX; coproporphyrinogen oxidase; coproporphyrinogen oxidase (coproporphyria, harderoporphyria) , CPO; coproporphyrinogen-III oxidase, mitochondrial; coproporphyria; CPX; HCP; COX; coprogen oxidase; coproporphyrinogenase; CPO;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CPOX-1807H Recombinant Human CPOX Protein, GST-tagged Wheat Germ GST
Human CPOX-527H Recombinant Human coproporphyrinogen oxidase, His-tagged E.coli His
Human CPOX-2107HF Recombinant Full Length Human CPOX Protein, GST-tagged In Vitro Cell Free System GST 454 amino acids
Mouse CPOX-3855M Recombinant Mouse CPOX Protein Mammalian Cell His
Mouse CPOX-1939M Recombinant Mouse CPOX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CPOX-1939M-B Recombinant Mouse CPOX Protein Pre-coupled Magnetic Beads HEK293
Rat CPOX-1570R Recombinant Rat CPOX Protein Mammalian Cell His
Rat CPOX-1227R-B Recombinant Rat CPOX Protein Pre-coupled Magnetic Beads HEK293
Rat CPOX-1227R Recombinant Rat CPOX Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CPOX-3723Z Recombinant Zebrafish CPOX Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CPOX involved in several pathways and played different roles in them. We selected most pathways CPOX participated on our site, such as Heme Biosynthesis, Metabolic pathways, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPOX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Heme BiosynthesisCOX15;COX10;CPOX
Metabolic pathwaysATIC;TSTA3;CYP2P9;CHIA.3;SDS;CERS4;SDHA;HYI;SDHC
MetabolismBPNT1;GNG13B;DDAH1;HIBADH;SACM1L;MED31;MED6;NUBP2;NUDT4A
Metabolism of porphyrinsUGT1B4;UGT1B2;COX10;UGT1B1;COX15;UGT1B5;UGT1B3;UGT1B7;CPOX
Porphyrin and chlorophyll metabolismUGT2A1;ALAD;UGT2B7;UGT2A3;UGT1A2;FECH;CP;EPRS;HMBSB
heme biosynthesis I (aerobic)

CPOX has several biochemical functions, for example, coproporphyrinogen oxidase activity, protein homodimerization activity, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by CPOX itself. We selected most functions CPOX had, and list some proteins which have the same functions with CPOX. You can find most of the proteins on our site.

Function Related Protein
coproporphyrinogen oxidase activityRSAD1;CPOX
protein homodimerization activityGJC3;MUC13;SFTPC;LRRFIP1;CARD9;TMEM173;CPOX;ABCB9;CD2
structural constituent of eye lensCRYAA;BFSP2;MIP;CRYAB;LIM2.5;LIM2.3;CRYGC;CRYBA1;LIM2.1

CPOX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPOX here. Most of them are supplied by our site. Hope this information will be useful for your research of CPOX.

UBE2G2; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine; Fech; Cpox; Slc25a4; Ppox; Slc25a5; Vdac2; Abcb7; Glrx5; Slc25a11; Abcb10

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