CPOX Protein, coproporphyrinogen oxidase


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Official Full Name coproporphyrinogen oxidase
Background The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
Synonyms CPOX; coproporphyrinogen oxidase; coproporphyrinogen oxidase (coproporphyria, harderoporphyria) , CPO; coproporphyrinogen-III oxidase, mitochondrial; coproporphyria; CPX; HCP; COX; coprogen oxidase; coproporphyrinogenase; CPO
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CPOX-1807H Recombinant Human CPOX Protein, GST-tagged Wheat Germ GST
    Human CPOX-527H Recombinant Human coproporphyrinogen oxidase, His-tagged E.coli His
    Mouse CPOX-3855M Recombinant Mouse CPOX Protein Mammalian Cell His
    Rat CPOX-1570R Recombinant Rat CPOX Protein Mammalian Cell His
    Zebrafish CPOX-3723Z Recombinant Zebrafish CPOX Mammalian Cell His

    CPOX involved in several pathways and played different roles in them. We selected most pathways CPOX participated on our site, such as Heme Biosynthesis, Metabolic pathways, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CPOX were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Heme Biosynthesis COX15; COX10; CPOX
    Metabolic pathways GALNT18; FUT6; TBXAS1; AKR1B1L; MPI; ATP5F1; HSD17B6; IMPA2; MGAT1B; HIBADH
    Metabolism SCP2B; ACOT8; CYP24A1; EPM2A; CYP3A7; MED22; BRP44; CYP17A1; ACOT10; SLC25A16
    Metabolism of porphyrins UGT1B4; COX15; UGT1B3; UGT1B5; CPOX; UGT1B7; COX10; UGT1B1; UGT1B2
    Porphyrin and chlorophyll metabolism UGT2A2; UGT1A9; UGT1A7; MMAB; UGT1A3; FECH; UGT1A2; HMOX2A; EPRS; BLVRB
    heme biosynthesis I (aerobic) CPOX

    CPOX has several biochemical functions, for example, coproporphyrinogen oxidase activity, protein homodimerization activity, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by CPOX itself. We selected most functions CPOX had, and list some proteins which have the same functions with CPOX. You can find most of the proteins on our site.

    Function Related Protein
    coproporphyrinogen oxidase activity CPOX; RSAD1
    protein homodimerization activity ATPIF1; NKX2; NR6A1; TERF1; PVRL1A; GPD1C; TERT; DDX1; TIMELESS; AMICA1
    structural constituent of eye lens HSPB6; CRYBA4; LIM2.5; ASL1; BFSP1; CRYAA; BFSP2; MIP; CRYBB2; CRYGF

    CPOX has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CPOX here. Most of them are supplied by our site. Hope this information will be useful for your research of CPOX.

    UBE2G2; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine; Fech; Cpox; Slc25a4; Ppox; Slc25a5; Vdac2; Abcb7; Glrx5; Slc25a11; Abcb10

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