CYP20A1 Protein, cytochrome P450, family 20, subfamily A, polypeptide 1

CYP20A1

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CYP20A1

Official Full Name cytochrome P450, family 20, subfamily A, polypeptide 1
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen.
Synonyms CYP20A1; cytochrome P450, family 20, subfamily A, polypeptide 1; cytochrome P450 20A1; CYP M; CP20A_HUMAN; Cytochrome P450 monooxygenase; MGC22229; CYP-M
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CYP20A1-11767H Recombinant Human CYP20A1, His-tagged E.coli His
    Human CYP20A1-2248H Recombinant Human CYP20A1 Protein, GST-tagged Wheat Germ GST
    Human CYP20A1-7124HCL Recombinant Human CYP20A1 293 Cell Lysate HEK293 N/A
    Mouse CYP20A1-4151M Recombinant Mouse CYP20A1 Protein Mammalian Cell His
    Rat CYP20A1-1718R Recombinant Rat CYP20A1 Protein Mammalian Cell His
    Zebrafish CYP20A1-12517Z Recombinant Zebrafish CYP20A1 Mammalian Cell His

    CYP20A1 involved in several pathways and played different roles in them. We selected most pathways CYP20A1 participated on our site, such as cytochrome P450, metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP20A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cytochrome P450 CYP4F12; CYP20A1; CYB5R3; CYP4V2; POR; CYP2W1; CYB5B; CYB5A; CYP2A7; CYP4Z1
    metapathway biotransformation SULT1B1; NAA50; SULT6B1; NAT9; PRKRA; NAA40; KCNAB1; CEACAM21; NAT8B; CYP20A1

    CYP20A1 has several biochemical functions, for example, heme binding, iron ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP20A1 itself. We selected most functions CYP20A1 had, and list some proteins which have the same functions with CYP20A1. You can find most of the proteins on our site.

    Function Related Protein
    heme binding CBSA; CYP27A1; HBAD; CYP2N13; CYP2R1; CYP1B1; CYP2C38; CYP2AA3; CYP21A1; CYP2P6
    iron ion binding HBB-B2; CYP2AA6; LTF; CYP46A1.2; CYP2AD2; CYP2E1; SLC11A2; ALKBH8; OGFOD2; CYP11C1
    monooxygenase activity CYP3A43; CYP2D6; CYP2B19; CYP2D9; CYP19A1A; CYP2Y3; CYP2AA7; FAM84B; CYP2AD6; CYP2AA6
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen LEPREL1; CYP2B19; CYP4F18; CYP4A14; CYP1C2; CYP4T8; CYP2C50; CYP26C1; CYP2AA7; CYP2AA9

    CYP20A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP20A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP20A1.

    Rrbp1

    Nyante, SJ; Gammon, MD; et al. Genetic variation in estrogen and progesterone pathway genes and breast cancer risk: an exploration of tumor subtype-specific effects. CANCER CAUSES & CONTROL 26:121-131(2015).
    Zou, JG; Ma, YT; et al. The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China. LIPIDS IN HEALTH AND DISEASE 13:-(2014).

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