CYP4F11 Protein, cytochrome P450, family 4, subfamily F, polypeptide 11


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Official Full Name cytochrome P450, family 4, subfamily F, polypeptide 11
Background This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms CYP4F11; cytochrome P450, family 4, subfamily F, polypeptide 11; cytochrome P450, subfamily IVF, polypeptide 11; cytochrome P450 4F11; CYPIVF11
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Wheat Germ
    • Tag :
    • GST
    • His
    • SUMO
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CYP4F11-1130H Recombinant Human CYP4F11 Protein (38-524 aa), His-SUMO-tagged E.coli His/SUMO
    Human CYP4F11-11789H Recombinant Human CYP4F11, GST-tagged E.coli GST
    Human CYP4F11-2282H Recombinant Human CYP4F11 Protein, GST-tagged Wheat Germ GST
    Human CYP4F11-7103HCL Recombinant Human CYP4F11 293 Cell Lysate HEK293 N/A

    CYP4F11 involved in several pathways and played different roles in them. We selected most pathways CYP4F11 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4F11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism GPX2; PTGS2A; CYP2P9; CYP2C39; PLA2G3; PTGDSB; CBR1L; PTGDS; PLA2G2E; GGT1A
    Biological oxidations CYP2C8; CYP2E1; ADH1A; CYP2D6; SULT2ST2; CYP2K18; CYP2C9; CYP3C4; CYP1A1; FAM84B
    Cytochrome P450 - arranged by substrate type CYP11A1; CYP2J2; POMCB; CYP27B1; CYP2N13; CYP2K17; CYP2C8; CYP4F12; CYP3A4; CYP2D6
    Eicosanoids CYP4F12; CYP4F11; CYP4F22; CYP4A11; CYP4B1
    Fatty acids CYP2AD6; CYP4T8; CYP4F12; CYP2D6; CYP2N13; CYP2V1; CYP2AD3; CYP4F11; CYP2A13; CYP2F1
    Metabolism SCP2B; ACOT9.1; AKR1C21; OAZ1A; ADSS; SLC27A2; NUDT15; SLC6A7; AKR1C2; GCHFR
    Metabolism of lipids and lipoproteins CYP46A1; CYP27B1; FA2H; ALOX5AP; CSNK1G2; CYP11B1; PLBD1; CHAT; DPEP2; CERS4A
    Miscellaneous substrates CYP4F22; CYP2K22; CYP2K18; CYP2W1; CYP2U1; CYP2K8; CYP2K19; CYP3C1; CYP2S1; CYP2K17

    CYP4F11 has several biochemical functions, for example, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4F11 itself. We selected most functions CYP4F11 had, and list some proteins which have the same functions with CYP4F11. You can find most of the proteins on our site.

    Function Related Protein
    heme binding CYP2C55; CYP2X10.2; NGB; CYP3A7; CYP4V8; CYP2C54; FA2H; CYP4A11; FAM84B; FECH
    iron ion binding CYGB1; CYP11C1; HBG2; P4HA1A; P4HA3; PLOD1A; HBG1; CALR; P4HTM; NOS2A
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen MTRR; MICAL1; CYP4F2; COQ6; CYP11A1; CYP11B2; CYP4F18; CYP11B1; POR; NDOR1

    CYP4F11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4F11 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4F11.


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