CYP4F22 Protein, cytochrome P450, family 4, subfamily F, polypeptide 22


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Official Full Name cytochrome P450, family 4, subfamily F, polypeptide 22
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3.
Synonyms CYP4F22; cytochrome P450, family 4, subfamily F, polypeptide 22; cytochrome P450 4F22; FLJ39501; CP4FN_HUMAN; FLJ 39501; LI3; cytochrome P450, family 2, subfamily E, polypeptide 2 homolog
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CYP4F22-2284H Recombinant Human CYP4F22 Protein, GST-tagged Wheat Germ GST
    Human CYP4F22-7101HCL Recombinant Human CYP4F22 293 Cell Lysate HEK293 N/A
    Rhesus Macaque CYP4F22-1163R Recombinant Rhesus monkey CYP4F22 Protein, His-tagged Mammalian Cell His

    CYP4F22 involved in several pathways and played different roles in them. We selected most pathways CYP4F22 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4F22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP4B1; CYP2U1; CYP2P10; LTC4S; CBR3; CYP2B19; CYP1B1; PTGR1; PLA2G10; CYP2C19
    Biological oxidations FDXR; CYP2Y3; CYP2C19; CYP4B1; CYP2K18; CYP1A2; CYP3A7-CYP3AP1; AS3MT; SLC35B3; CYP2AD6
    Cytochrome P450 - arranged by substrate type CYP2C9; CYP3A4; FDXR; CYP2V1; CYP26A1; CYP3A7; CYP27A1; CYP27B1; CYP4B1; CYP4T8
    Eicosanoids CYP4F11; CYP4A11; CYP4F12; CYP4B1; CYP4F22
    Fatty acids CYP2AD6; CYP2A7; CYP2B6; CYP4F22; CYP2V1; CYP4F11; CYP4F12; CYP4A11; CYP2F1; CYP2N13
    Metabolism of lipids and lipoproteins MTP; CYP2AD2; PIK3R6; TIAM2; MED31; SPTLC1; SGMS2; DGAT1B; MED8; ECI1
    Miscellaneous substrates CYP2K19; CYP3C4; CYP2K22; CYP4F22; CYP2K17; CYP2U1; CYP3C1; CYP2K6; CYP2K16; CYP2K8

    CYP4F22 has several biochemical functions, for example, heme binding, iron ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4F22 itself. We selected most functions CYP4F22 had, and list some proteins which have the same functions with CYP4F22. You can find most of the proteins on our site.

    Function Related Protein
    heme binding CYP2A4; CYP2AA1; CYP2S1; FAM84B; CYGB2; CBSA; CYP4F12; CYP2AA6; CYP3A5; CYP11B1
    iron ion binding CYP11C1; FAM84B; PDF; CYP26A1; ALOX5; CYP2C37; TPH1; CYP1A4; CYP3C4; ALOX15B
    monooxygenase activity CYP2D10; CYP11C1; CYP2C9; CYP2D6; CYP2K16; CYP2X8; CYP4F22; CYP21A1; CYP2C70; CYP4V8
    oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen CYP26C1; CYP2C38; CYP2AA4; CYP4A12A; CYP2D9; CYP2X7; EGLN1B; CYP2AA6; CYP2J5; CYP8B2

    CYP4F22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4F22 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4F22.

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