|Official Full Name||cytochrome P450, family 4, subfamily F, polypeptide 22|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3.|
|Synonyms||CYP4F22; cytochrome P450, family 4, subfamily F, polypeptide 22; cytochrome P450 4F22; FLJ39501; CP4FN_HUMAN; FLJ 39501; LI3; cytochrome P450, family 2, subfamily E, polypeptide 2 homolog|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CYP4F22 involved in several pathways and played different roles in them. We selected most pathways CYP4F22 participated on our site, such as Arachidonic acid metabolism, Biological oxidations, Cytochrome P450 - arranged by substrate type, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP4F22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Arachidonic acid metabolism||CYP4B1; CYP2U1; CYP2P10; LTC4S; CBR3; CYP2B19; CYP1B1; PTGR1; PLA2G10; CYP2C19|
|Biological oxidations||FDXR; CYP2Y3; CYP2C19; CYP4B1; CYP2K18; CYP1A2; CYP3A7-CYP3AP1; AS3MT; SLC35B3; CYP2AD6|
|Cytochrome P450 - arranged by substrate type||CYP2C9; CYP3A4; FDXR; CYP2V1; CYP26A1; CYP3A7; CYP27A1; CYP27B1; CYP4B1; CYP4T8|
|Eicosanoids||CYP4F11; CYP4A11; CYP4F12; CYP4B1; CYP4F22|
|Fatty acids||CYP2AD6; CYP2A7; CYP2B6; CYP4F22; CYP2V1; CYP4F11; CYP4F12; CYP4A11; CYP2F1; CYP2N13|
|Metabolism||OSBP; CRAT; ESRRA; CTRC; COX14; CDO1; FAM96B; CTRB1; GPC5A; ITPKA|
|Metabolism of lipids and lipoproteins||MTP; CYP2AD2; PIK3R6; TIAM2; MED31; SPTLC1; SGMS2; DGAT1B; MED8; ECI1|
|Miscellaneous substrates||CYP2K19; CYP3C4; CYP2K22; CYP4F22; CYP2K17; CYP2U1; CYP3C1; CYP2K6; CYP2K16; CYP2K8|
CYP4F22 has several biochemical functions, for example, heme binding, iron ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP4F22 itself. We selected most functions CYP4F22 had, and list some proteins which have the same functions with CYP4F22. You can find most of the proteins on our site.
|heme binding||CYP2A4; CYP2AA1; CYP2S1; FAM84B; CYGB2; CBSA; CYP4F12; CYP2AA6; CYP3A5; CYP11B1|
|iron ion binding||CYP11C1; FAM84B; PDF; CYP26A1; ALOX5; CYP2C37; TPH1; CYP1A4; CYP3C4; ALOX15B|
|monooxygenase activity||CYP2D10; CYP11C1; CYP2C9; CYP2D6; CYP2K16; CYP2X8; CYP4F22; CYP21A1; CYP2C70; CYP4V8|
|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen||CYP26C1; CYP2C38; CYP2AA4; CYP4A12A; CYP2D9; CYP2X7; EGLN1B; CYP2AA6; CYP2J5; CYP8B2|
CYP4F22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP4F22 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP4F22.