cdc25b
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  • Official Full Name
  • cell division cycle 25 homolog B
  • Background
  • cdc25 is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic cells into mitosis. cdc25C is constitutively phosphorylated at Ser216 throughout interphase by c-TAK1, while pho
  • Synonyms
  • CDC25B; cell division cycle 25 homolog B (S. pombe); cell division cycle 25 homolog B (S. cerevisiae) , cell division cycle 25B; M-phase inducer phosphatase 2; cell division cycle 25B; dual specificity phosphatase Cdc25B
Cat.#:CDC25B-0916HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDC25B Protein, GST-Tagged
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Cat.#:CDC25B-11000HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDC25B, His-tagged
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Cat.#:CDC25B-547HTag:Met|His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDC25B Protein, Met & His-tagged
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Cat.#:CDC25B-1272RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CDC25B Protein
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Cat.#:CDC25B-6535ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDC25B
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Cat.#:CDC25B-1512HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human CDC25B (Active), GST-tagged
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Cat.#:CDC25B-7665HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CDC25B 293 Cell Lysate
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Cat.#:CDC25B-7666HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human CDC25B 293 Cell Lysate
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Involved Pathway

Cdc25b involved in several pathways and played different roles in them. We selected most pathways Cdc25b participated on our site, such as MAPK signaling pathway, Cell cycle, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cdc25b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
ACVR1C; RELB; NLK2; MRAS; SOS1; FGF13A; FGF7; MAP2K5; JIP1; MKNK2B
Cell cycle
CENPA; LIN9; RNF168; CEP164; KIF18A; NDE1; HDAC1; DCTN2; CENPE; FGFR1OP
Progesterone-mediated oocyte maturation
CDC26; PRKACAA; MAPK1; CPEB2; FZR1; CCNB3; ADCY1A; PRKACA; PIK3CB; MAPK8
MicroRNAs in cancer
BRCA1; ABL1; ROCK1; CCND1; PRKCG; NOTCH2; GRB2; MAP2K1; TP63; NOTCH1

Protein Function

Cdc25b has several biochemical functions, for example, protein binding, protein kinase binding, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cdc25b itself. We selected most functions Cdc25b had, and list some proteins which have the same functions with Cdc25b. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein TYROBP; IER3; RIC8; SERPINB5; RBL1; CDA; OSBPL7; FKBP4; ACO1; CCDC47
Function protein kinase binding
Related Protein SPDYE2; FOXO3; PAK2; FOXM1; ACVRL1; TP53; CDC42; FGR; RICTOR; CCND3
Function protein tyrosine phosphatase activity
Related Protein EYA3; PTPN23A; CDC25D; PTPN22; PTEN; UBASH3B; DUSP3; PTPN7; PTPN3; TPTE

Interacting Protein

Cdc25b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cdc25b here. Most of them are supplied by our site. Hope this information will be useful for your research of Cdc25b.
YWHAZ; YWHAB; YWHAH

Cdc25b Related Articles

Lee, KH; Tsutsui, T; et al. Overexpression of mutant cell division cycle 25 homolog B (CDC25B) enhances the efficiency of selection in Chinese hamster ovary cells. CYTOTECHNOLOGY 65:1017-1026(2013).
Kang, H; Hwang, SC; et al. Cdc25B phosphatase participates in maintaining metaphase II arrest in mouse oocytes. MOLECULES AND CELLS 35:514-518(2013).