dao
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  • Official Full Name
  • D-amino-acid oxidase
  • Background
  • This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
  • Synonyms
  • DAO; D-amino-acid oxidase; DAMOX; DAAO; DAO1; EC 1.4.3.3; MGC35381; OXDA; OXDA_HUMAN; D-amino acid oxidase
Cat.#:DAO-1375HTag:His
Source (Host):YeastSpecies:Human
Product nameRecombinant Human DAO Protein (1-347 aa), His-tagged
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Cat.#:DAO-2573RTag:His|Myc
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat DAO Protein (1-346 aa), His-Myc-tagged
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Cat.#:DAO-1181HTag:His|SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DAO Protein, His-SUMO-tagged
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Cat.#:DAO-2330HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DAO Protein, GST-tagged
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Cat.#:CED055Tag:N/A
Source (Host):Porcine KidneySpecies:Pig
Product namePorcine D-Amino Acid Oxidase
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Cat.#:DAO-11821HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DAO, GST-tagged
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Cat.#:DAO-392HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human DAO Protein, His-tagged
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Cat.#:DAO-476HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human D-amino-acid Oxidase, His-tagged
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Cat.#:DAO-4302MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DAO Protein
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Cat.#:DAO-1773RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DAO Protein
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Cat.#:DAO-448CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus DAO Protein, His-tagged
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Cat.#:DAO1-25PTag:N/A
Source (Host):Species:Pig
Product nameNative Porcine D-Amino acid oxidase
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Cat.#:DAO-216HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human DAO lysate
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Cat.#:Kit-1074Tag:N/A
Source (Host):Species:
Product nameDiamine Oxidase Activity Assay Kit (Fluorometric)
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Cat.#:Kit-2071Tag:N/A
Source (Host):Species:
Product nameDiamine Oxidase Assay Kit
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Involved Pathway

DAO involved in several pathways and played different roles in them. We selected most pathways DAO participated on our site, such as Arginine and proline metabolism, Biosynthesis of antibiotics, D-Arginine and D-ornithine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Arginine and proline metabolism
ALDH2.1; DAO.2; ABP1; PRODH; ALDH9A1A.1; ALDH7A1; DAO; SAT1; PYCR1B; L3HYPDH
Biosynthesis of antibiotics
DLST; AK7; LDHAL6B; CS; CMBL; GLYCTK; GPR19; ACAA2; ADSL; SDSL
D-Arginine and D-ornithine metabolism
DAO.2; DAO.1; DAO.3; DAO; DAO1
Glycine, serine and threonine metabolism
GAMT; GLDC; PGAM1A; DAO; DAO1; ALDH7A1; BPGM; GRHPR; AOC2; SARDH
Glyoxylate metabolism and glycine degradation
AGXT; DAO; DAO1
Metabolic pathways
TYRP1B; TBXAS1; NDUFS1; NME5; PLA2G2D; ALG2; GLDC; COQ2; HSD17B12; ENO3
Metabolism
SLC27A2A; PLBD1; GPAT2; CDK19; ACSM1; ACY3.2; ADSS; DAO; ARSE; CYP2K19
Metabolism of amino acids and derivatives
NAGS; CKMT2A; AZIN1; AZIN1A; TPH2; CTHL; ACMSD; NQO1; IVD; BHMT2

Protein Function

DAO has several biochemical functions, for example, D-amino-acid oxidase activity, FAD binding, cofactor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAO itself. We selected most functions DAO had, and list some proteins which have the same functions with DAO. You can find most of the proteins on our site.
Function
Related Protein
Function D-amino-acid oxidase activity
Related Protein DAO1; DAO.1; DAO.2; DAO; DAO.3
Function FAD binding
Related Protein DDO; CYB5R3; KMO; DAO.3; COQ6; MICAL1; DAO.2; DAO1; DERL3; MTRR
Function cofactor binding
Related Protein ASNS; LMO2; PHYH; DDO; ME3; HACL1; PAH; ACLYA; HIF1AN; BIRC5
Function protein binding
Related Protein RPL7A; UBQLN4; UBASH3B; PBX4; SREBF2; RAI1; UBAC1; RHOC; CANX; HIST1H4K
Function protein dimerization activity
Related Protein MITF; ZBED1; LYL1; POLR2J; HEY2; HPSE; SREBF2; HES3; SRFB; TCF21
Function receptor binding
Related Protein ITGA1; MYO1C; CRH; IDH1; KCNA5; PTK6B; WNT4A; KNG1; CXCL10; RCHY1

Interacting Protein

DAO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAO here. Most of them are supplied by our site. Hope this information will be useful for your research of DAO.
PRKAB2; EP300

DAO Related Articles

Nishimura, Y; Tanaka, H; et al. Immunohistochemical localization of D-serine dehydratase in chicken tissues. ACTA HISTOCHEMICA 116:702-707(2014).
Schwelberger, HG; Feurle, J; et al. New tools for studying old questions: antibodies for human diamine oxidase. JOURNAL OF NEURAL TRANSMISSION 120:1019-1026(2013).