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DAO

  • Official Full Name

    D-amino-acid oxidase

  • Overview

    This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
  • Synonyms

    DAO; D-amino-acid oxidase; DAMOX; DAAO; DAO1; EC 1.4.3.3; MGC35381; OXDA; OXDA_HUMAN; D-amino acid oxidase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Native Proteins
  • Assay Kits
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Pig
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Porcine Kidney
  • Wheat Germ
  • Yeast
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|Myc
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DAO-392H Active Recombinant Human DAO Protein, His-tagged E.coli His
Human DAO-2330H Recombinant Human DAO Protein, GST-tagged Wheat Germ GST
Human DAO-476H Recombinant Human D-amino-acid Oxidase, His-tagged E.coli His
Human DAO-1181H Recombinant Human DAO Protein, His-SUMO-tagged E.coli His/SUMO
Human DAO-11821H Recombinant Human DAO, GST-tagged E.coli GST 24-347a.a.
Human DAO-216HCL Recombinant Human DAO lysate HEK293 N/A
Human DAO-1375H Recombinant Human DAO Protein (1-347 aa), His-tagged Yeast His 1-347 aa
Human DAO-1307H Recombinant Human DAO Protein, His-tagged E.coli N-His Met1-Leu347
Human DAO-2379HF Recombinant Full Length Human DAO Protein, GST-tagged In Vitro Cell Free System GST 347 amino acids
Mouse DAO-4302M Recombinant Mouse DAO Protein Mammalian Cell His
Mouse DAO-2198M Recombinant Mouse DAO Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DAO-2198M-B Recombinant Mouse DAO Protein Pre-coupled Magnetic Beads HEK293
Rat DAO-1773R Recombinant Rat DAO Protein Mammalian Cell His
Rat DAO-2573R Recombinant Rat DAO Protein (1-346 aa), His-Myc-tagged E.coli His/Myc 1-346 aa
Rat DAO-1431R Recombinant Rat DAO Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Dao-1265R Recombinant Rat Dao protein, His&Myc-tagged Insect Cell His&Myc 1-346aa
Rat DAO-1431R-B Recombinant Rat DAO Protein Pre-coupled Magnetic Beads HEK293
Rat Dao-1301R Recombinant Rat Dao protein, His&Myc-tagged HEK293 His&Myc 1-346aa
Cynomolgus Monkey DAO-448C Recombinant Cynomolgus DAO Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey DAO-194C-B Recombinant Cynomolgus Monkey DAO Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey DAO-194C Recombinant Cynomolgus Monkey DAO Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Pig CED055 Active Porcine D-Amino Acid Oxidase Porcine Kidney N/A
Pig DAO1-25P Active Native Porcine D-Amino acid oxidase Porcine Kidney N/A 347 aa
Kit-2071 Diamine Oxidase Assay Kit N/A
Kit-1074 Diamine Oxidase Activity Assay Kit (Fluorometric) N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DAO Related Articles

DAO involved in several pathways and played different roles in them. We selected most pathways DAO participated on our site, such as Arginine and proline metabolism, Biosynthesis of antibiotics, D-Arginine and D-ornithine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Arginine and proline metabolismSRM;ALDH7A1;LAP3;GOT1;PYCR1B;ARG1;DAO;P4HA1;PYCR1A
Biosynthesis of antibioticsDLST;ANI_1_2390104;LDHAL6A;SDS;DBT;ACAA2;CMBL;pykF;GALM
D-Arginine and D-ornithine metabolismDAO.1;DAO.2;DAO;DAO.3;DAO1
Glycine, serine and threonine metabolismCBSA;CTH;SARDH;AGXTA;DAO;ALDH7A1;GCSH;PIPOX;PGAM2
Glyoxylate metabolism and glycine degradationDAO1;AGXT;DAO
Metabolic pathwaysQDPRB2;NME1-NME2;ASMT;RRM2;PRPS1;MAT1A;COMTB;PDHA1B;APIP
MetabolismCYP4F11;ELA2L;CERS5;ABHD4;UGT1B7;COX14;SLC26A2;SLC6A7;CYP27B1
Metabolism of amino acids and derivativesCRYM;FTCD;CKMT2A;OAZ1A;OAZ1;BCKDK;UROC1;OAZ2;GLS2B

DAO has several biochemical functions, for example, D-amino-acid oxidase activity, FAD binding, cofactor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAO itself. We selected most functions DAO had, and list some proteins which have the same functions with DAO. You can find most of the proteins on our site.

Function Related Protein
D-amino-acid oxidase activityDAO;DAO.3;DAO.1;DAO1;DAO.2
FAD bindingDAO.1;CYB5R3;PRODH;DAO.3;AGPS;KMO;MICAL2;DAO;ACOX1
cofactor bindingBIRC5;WWOX;ACLYA;TYMS;DAO;LMO2;ME3;PAH;TKT
protein bindingAKR1A1;ZBTB24;SPC24;ABHD1;U2AF1;GNB1;HMG20B;ORC3L;PPP2R5B
protein dimerization activityOLIG1;NEUROG2;MITF;BETA3;MYCLB;SIM1;ARNTL1A;DAO;DNM1
receptor bindingFGF10A;PTK2AB;MLYCD;CADM3;CD276;APP;HLA-G;CD86;Artn

DAO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAO here. Most of them are supplied by our site. Hope this information will be useful for your research of DAO.

PRKAB2; EP300

Nishimura, Y; Tanaka, H; et al. Immunohistochemical localization of D-serine dehydratase in chicken tissues. ACTA HISTOCHEMICA 116:702-707(2014).
Schwelberger, HG; Feurle, J; et al. New tools for studying old questions: antibodies for human diamine oxidase. JOURNAL OF NEURAL TRANSMISSION 120:1019-1026(2013).
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