DDX3X Protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

DDX3X

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DDX3X

Official Full Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.
Synonyms ATP dependent RNA helicase DDX3X; DEAD box protein 3 X-chromosomal; DEAD box X isoform; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; HLP2
    • Species :
    • Chicken
    • Human
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • B2M
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DDX3X-2222H Recombinant Human DDX3X Protein (2-662 aa), His-B2M-tagged E.coli His/B2M
    Human DDX3X-257H Recombinant Human DDX3X protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DDX3X-28325TH Recombinant Human DDX3X protein, GST-tagged Wheat Germ GST
    Human DDX3X-7007HCL Recombinant Human DDX3X 293 Cell Lysate HEK293 N/A
    Chicken DDX3X-2498C Recombinant Chicken DDX3X Mammalian Cell His

    DDX3X involved in several pathways and played different roles in them. We selected most pathways DDX3X participated on our site, such as Hepatitis B, RIG-I-like receptor signaling pathway, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX3X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hepatitis B NFATC2; IFNA12; NFKB1; IFNB1; TBK1; MAP2K1; CCNA1; MMP9; STAT5B; TGFB1
    RIG-I-like receptor signaling pathway NFKB1; MAPK11; RNF125; IFNA3; IFNA6; IFNB; IKBKE; MAPK12; IFNA12; NLRX1
    TNF-alpha/NF-kB Signaling Pathway G3BP2; PPP1R13L; MARK2; PDCD2; DCAF7; TANK; DPF2; PEG3; DDX3X; AKAP8
    Viral carcinogenesis SRC; SP100; SRF; HDAC4; GTF2B; HIST1H2BO; HDAC9; ATP6V0D2; IRF3; TTC6

    DDX3X has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX3X itself. We selected most functions DDX3X had, and list some proteins which have the same functions with DDX3X. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PEX6; TRIT1; EHD1; MYO5B; MAPK15; PMS2; PRKG1; RUNX2A; MARK2; ULK2
    ATP-dependent DNA helicase activity BLM; CHD2; CHD4; DHX9; ERCC3; CHD1; FBXO18; XRCC6; RUVBL2; XRCC5
    ATP-dependent RNA helicase activity DHX8; DQX1; EIF4A1A; DDX59; DDX20; DDX53; DDX28; CHST13; DDX10; DDX19B
    ATPase activity ABCG2D; SWSAP1; BLM; PSMC2; ABCD3A; KIF3CB; ABCB3L1; PICK1; DYNC1H1; KIFC2
    CTPase activity DDX3X
    DNA binding GTF2A1L; HIST1H4I; ASXL2; HNRNPU; ASCL1A; HIST1H2BD; HNRPK; SOX21B; EBF3A; TCEB3C
    GTPase activity RAB35; GNL3L; MX1; RAB39B; RAB5AA; MFN1; TUBA8L; RAB18A; GTPBP4; RAB1BB
    RNA binding RNASEL; ADAT1; EIF2C3; RAVER2; MKI67IP; XPO1; SRP14; RBMS3; NANOS1; NHP2L1B
    RNA stem-loop binding EPRS; CPEB3; DDX3X; DAZAP1
    eukaryotic initiation factor 4E binding GRA; EIF4EBP3L; EIF4EBP1; ANGEL1; DDX3X; LARP1; EIF4EBP2; HHEX; EIF4G1; OTX2
    mRNA 5-UTR binding LARP1; DDX3X; MRPS11; IGF2BP1; RPS14; IGF2BP2; IGF2BP3
    nucleoside-triphosphatase activity DDX3X; NTPCR; ENTPD6; ENTPD3; ENTPD8; ENTPD1
    poly(A) RNA binding ACAA2; POU5F1; MRPS23; MTDH; ERI3; KRT18; RPL19; DDX21; RPL10A; MADD
    poly(A) binding KHDRBS1; PABPC1; PAIP2B; HNRNPDL; PABPN1; EIF4A3; PABPC3; PABPC4; DDX3X; ZC3H14
    protein binding FBN1; DUSP12; ISCA2; DTX3; SOX30; ATPAF1; ATE1; IL12A; UXT; MS4A12
    ribosomal small subunit binding CPEB2; MTIF3; PTCD3; DDX3X; ERAL1; NME1; DHX29; PIM1; NPM1
    transcription factor binding HYAL1; ATG7; PER1; FIGLA; FLNA; TNFRSF10A; TBX5; NCOA2; HHEX; GPX3
    translation initiation factor binding TRIM32; LARP1; LIN28A; EIF3C; DDX3X; POLR2G; RPS24; ZFP259; EIF2B4; CELF1

    DDX3X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX3X here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX3X.

    p27958-pro_0000037566; PABPC1

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