dlg3
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  • Official Full Name
  • Dlg3 discs, large homolog 3 (Drosophila)
  • Synonyms
  • DLG3; discs, large homolog 3 (Drosophila); disks large homolog 3; SAP-102; discs large homolog 3; synapse-associated protein 102; Dlgh3; SAP102; mKIAA1232;
Cat.#:DLG3-2676HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DLG3 Protein, GST-tagged
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Cat.#:DLG3-560HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DLG3 Protein, His-tagged
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Cat.#:DLG3-1880RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DLG3 Protein
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Cat.#:DLG3-1277RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DLG3 Protein, His-tagged
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Cat.#:DLG3-6911HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DLG3 293 Cell Lysate
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Involved Pathway

DLG3 involved in several pathways and played different roles in them. We selected most pathways DLG3 participated on our site, such as Activation of Ca-permeable Kainate Receptor, Activation of Kainate Receptors upon glutamate binding, Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLG3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of Ca-permeable Kainate Receptor
DLG1L; DLG3; DLG4; NCALDA
Activation of Kainate Receptors upon glutamate binding
DLG3; GNB5; NCALDA; DLG1L; DLG4
Axon guidance
RANBP9; SEMA4A; LRRC4C; GPC1A; PLXNA1; FGF18B; EFNA5; NFATC4; EPHA4; PAK1
Developmental Biology
MARK3; CFC1; SEMA4D; BNIP2; CNKSR1; SREBF2; CD24; CDK19; EVL; IL17RD
Hippo signaling pathway
AREG; PPP2CB; WNT9B; BMP8B; WNT4; BMP4; SMAD4; FZD1; TCF7; SCRIB
Ionotropic activity of Kainate Receptors
DLG1L; DLG3; NCALDA
L1CAM interactions
DCX; RANBP9; NRP1A; SCN2A; SCN3A; DPYSL2B; NADL1.1; SDCBP; DPYSL2; SCN9A
Neuronal System
ABCC9; SLC1A2A; SLC1A7B; KCNS3A; SLC6A12; KCNA6A; CPLX1; KCNS2; GLS2B; SLC1A3A

Protein Function

DLG3 has several biochemical functions, for example, PDZ domain binding, guanylate kinase activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLG3 itself. We selected most functions DLG3 had, and list some proteins which have the same functions with DLG3. You can find most of the proteins on our site.
Function
Related Protein
Function PDZ domain binding
Related Protein CRIPT; ACVR2A; ERC1; GRIK5; PLEKHA2; GRID2; SLC9A3R1; FZD1; ATP2B3B; SLC22A12
Function guanylate kinase activity
Related Protein GUK1; GUK1A; DLG1L; GUK1B; DLG1; CASK; MPP1; CARD11; TJP2; DLG4B
Function ionotropic glutamate receptor binding
Related Protein CACNG2; DLG3; DLG2; IL1R1; DRD2; FLOT2; CANX; SHANK2; FUS; DLG1
Function kinase binding
Related Protein PTPN22; LDHA; DUSP12; JAKMIP1; ATF5; CDC37; BTG1; CEBPA; SNAI1; LDHB
Function phosphatase binding
Related Protein KIAA0649; CNST; PPP1R36; ELL; WNK1; PPP1R35; PPP1R21; DLG3; PPP1R26; PPP1R32
Function protein C-terminus binding
Related Protein PROP1; MID1IP1; YWHAB; YAP1; ITPR1; HRAS; MRE11A; CTGF; DLG1; DDX1
Function protein binding
Related Protein SQSTM1; INCENP; CIB2; RNF183; MASP1; PLIN5; MCRS1; LGALS9C; FUBP1; FAM113B
Function protein phosphatase binding
Related Protein SNX3; DRD1; STAT6; TRAF2; PARD3; FGF19; KCNN4; EIF2AK3; DRD1A; ERBB2
Function ubiquitin protein ligase binding
Related Protein TPI1; HIF1A; SPOP; SKI; CASP10; CKB; FOXO1; GLMN; VCP; PRKAR2B

Interacting Protein

DLG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLG3.
GDA; PPP1CA; KRT34; ABCA1; ANXA1; S100A3; HIST1H2BC; KRT85; CUL2; KRT31; KRT35; KLHDC3; KRT82; CAMK2A