dlg3
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  • Official Full Name
  • Dlg3 discs, large homolog 3 (Drosophila)
  • Synonyms
  • DLG3; discs, large homolog 3 (Drosophila); disks large homolog 3; SAP-102; discs large homolog 3; synapse-associated protein 102; Dlgh3; SAP102; mKIAA1232;
Cat.#:DLG3-2676HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DLG3 Protein, GST-tagged
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Cat.#:DLG3-560HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DLG3 Protein, His-tagged
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Cat.#:DLG3-1880RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DLG3 Protein
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Cat.#:DLG3-1277RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DLG3 Protein, His-tagged
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Cat.#:DLG3-6911HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DLG3 293 Cell Lysate
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Involved Pathway

DLG3 involved in several pathways and played different roles in them. We selected most pathways DLG3 participated on our site, such as Activation of Ca-permeable Kainate Receptor, Activation of Kainate Receptors upon glutamate binding, Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLG3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Activation of Ca-permeable Kainate Receptor
NCALDA; DLG4; DLG3; DLG1L
Activation of Kainate Receptors upon glutamate binding
DLG3; GNB5; DLG4; NCALDA; DLG1L
Axon guidance
NTN1B; GPC1B; Ntng2; CSK; PLXND1; SEMA5B; GDNF; EFNA2A; EPHB1; CXCL12
Developmental Biology
MED9; DPYSL5A; PRDM14; TCF4; LGI4; CSNK2A2; COL9A1A; SCN3A; EFNB2A; GDNF
Hippo signaling pathway
FZD10; AREG; ITGB2; TCF7L2; WNT5B; TGFBR1; ACTG1; WNT8A; YAP1; GSK3B
Ionotropic activity of Kainate Receptors
DLG3; NCALDA; DLG1L
L1CAM interactions
CNTN1; SCN4A; ANK2B; RANBP9; SCN3A; DPYSL2; CNTN6; SCN3B; SDCBP; EZRA
Neuronal System
KCNG4A; RERG; KCNF1; KCNAB3; KCNV1; PANX1; KCNA10; KCNC4; KCNK2B; KCNMB1

Protein Function

DLG3 has several biochemical functions, for example, PDZ domain binding, guanylate kinase activity, ionotropic glutamate receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLG3 itself. We selected most functions DLG3 had, and list some proteins which have the same functions with DLG3. You can find most of the proteins on our site.
Function
Related Protein
Function PDZ domain binding
Related Protein ARHGAP29; SLC9A3R2; SNTB1; F11R; SDC2; DLG1; CCDC88C; PROSAPIP1; SLC22A12; EXOC4
Function guanylate kinase activity
Related Protein MPP3; DLG3; DLG1; CARD11; DLG4B; DLG4; MPP2; TJP2; GUK1A; MPP1
Function ionotropic glutamate receptor binding
Related Protein SHANK3; SHANK1; DLG4; IL1R1; RAB4A; DLG3; DLG4B; CACNG2; NETO1; DLG2
Function kinase binding
Related Protein WWC2; TAX1BP1; HSP90AB1; SLC2A1; PFKM; TRIP6; UBQLN1; STRADA; BCL10; BARD1
Function phosphatase binding
Related Protein ELFN1; KLRAQ1; DLG1; SPRED1; KIAA0649; SMAD3; ELFN2; DZIP3; CRY1; MAPK3
Function protein C-terminus binding
Related Protein SDC1; MPDZ; SIRT1; EP300; DAB2; NPAT; PHB; PABPC1; VGLL3; HIC2
Function protein binding
Related Protein VEGFB; THAP3; USP36; COL10A1; RHBDL1; GSN; TAGLN; TEAD4; SLC3A2; SPCS1
Function protein phosphatase binding
Related Protein EGFR; MAP2K7; JAK1; JAK3; ROS1; JUPA; MAP3K5; PARD3; PIK3R2; CDC27
Function ubiquitin protein ligase binding
Related Protein CUL4A; POLR2A; MC1R; CASP10; NFKBIA; CXCR4; RRAGA; TRIB1; KCNQ3; UBE2G1

Interacting Protein

DLG3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLG3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLG3.
GDA; PPP1CA; KRT34; ABCA1; ANXA1; S100A3; HIST1H2BC; KRT85; CUL2; KRT31; KRT35; KLHDC3; KRT82; CAMK2A