dnajb6
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  • Official Full Name
  • DnaJ (Hsp40) homolog, subfamily B, member 6
  • Background
  • This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
  • Synonyms
  • DNAJB6; DnaJ (Hsp40) homolog, subfamily B, member 6; dnaJ homolog subfamily B member 6; MRJ; DJ4; DnaJ; DNAJ B6; DNJB6_HUMAN; Heat shock protein J2; HHDJ1; HSJ-2; HSJ2; MSJ-1; MSJ1; DnaJ-like 2 protein
Cat.#:DNAJB6-2740HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNAJB6 Protein, GST-tagged
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Cat.#:DNAJB6-26155THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJB6, His-tagged
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Cat.#:DNAJB6-3380HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNAJB6, His-tagged
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Cat.#:DNAJB6-4692MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DNAJB6 Protein
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Cat.#:DNAJB6-1902RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat DNAJB6 Protein
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Cat.#:DNAJB6-1286RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DNAJB6 Protein, His-tagged
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Cat.#:DNAJB6-1928CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DNAJB6
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Cat.#:DNAJB6-6883HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNAJB6 293 Cell Lysate
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Cat.#:DNAJB6-6884HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNAJB6 293 Cell Lysate
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Involved Pathway

DNAJB6 involved in several pathways and played different roles in them. We selected most pathways DNAJB6 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cellular response to heat stress
HSBP1; RPS19BP1; HSBP1B; NUP50; BAG3; HSPA12B; HDAC6; DNAJB6; DPF1; DNAJC7
Cellular responses to stress
HIST1H1D; LAMTOR2; TXN; RBB4L; BAG3; KAT5; UVRAG; EGLN3; WDR45L; NUP35
Regulation of HSF1-mediated heat shock response
C11orf73; BAG3; HSPA13; DNAJC2; DNAJC7; KIAA1967; DNAJB6; BAG5; ST13; HSPA7

Protein Function

DNAJB6 has several biochemical functions, for example, ATPase activator activity, DNA binding, chaperone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJB6 itself. We selected most functions DNAJB6 had, and list some proteins which have the same functions with DNAJB6. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase activator activity
Related Protein MYBPC3; ATP1B1; ATP1B3; DNAJC15; RAB4A; DNAJC10; DNAJC24; DNAJC19; TOR1AIP1; ATP1B2
Function DNA binding
Related Protein DDX3Y; FOXI3A; PNX; SALL3; LASS5; ZNF76; OTX1A; ATXN1L; ZFAND5; SMAD5
Function chaperone binding
Related Protein PFDN4; ERP29; BAG2; DNAJB6; HES1; SERPINA7; DLST; DNAJB1; SDF2L1; BAG3
Function heat shock protein binding
Related Protein APAF1; GRXCR2; BAX; HSPA8; PPID; SSUH2RS1; BCOR; DMPK; GPR37; DNAJC7
Function protein binding
Related Protein GLYAT; BNIP1; MTF1; PPP1R12C; BSG; SOSTDC1B; FAM103A1; EIF4A2; EMP1; GTF2F2
Function unfolded protein binding
Related Protein GRPEL2; SSUH2RS1; CCT4; DNAJA3B; UGGT1; DNAJB4; CCT6B; ST13; DNAJA4; HSPA1L

Interacting Protein

DNAJB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJB6.
KRT18; MLF1; MLF2; DYSF; SGCG; BRMS1; HSPA8; UBA1