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DNAJB6

  • Official Full Name

    DnaJ (Hsp40) homolog, subfamily B, member 6

  • Overview

    This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
  • Synonyms

    DNAJB6; DnaJ (Hsp40) homolog, subfamily B, member 6; dnaJ homolog subfamily B member 6; MRJ; DJ4; DnaJ; DNAJ B6; DNJB6_HUMAN; Heat shock protein J2; HHDJ1; HSJ-2; HSJ2; MSJ-1; MSJ1; DnaJ-like 2 protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DNAJB6-3380H Recombinant Human DNAJB6, His-tagged E.coli His
Human DNAJB6-26155TH Recombinant Human DNAJB6, His-tagged E.coli His 326 amino acids
Human DNAJB6-2740H Recombinant Human DNAJB6 Protein, GST-tagged Wheat Germ GST
Human DNAJB6-6883HCL Recombinant Human DNAJB6 293 Cell Lysate HEK293 N/A
Human DNAJB6-6884HCL Recombinant Human DNAJB6 293 Cell Lysate HEK293 N/A
Human DNAJB6-3983HF Recombinant Full Length Human DNAJB6 Protein, GST-tagged In Vitro Cell Free System GST 241 amino acids
Human DNAJB6-3230H Recombinant Human DNAJB6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DNAJB6-301233H Recombinant Human DNAJB6 protein, GST-tagged E.coli GST Met1-Lys241
Mouse DNAJB6-4692M Recombinant Mouse DNAJB6 Protein Mammalian Cell His
Mouse DNAJB6-2441M Recombinant Mouse DNAJB6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dnajb6-2600M Recombinant Mouse Dnajb6 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DNAJB6-2441M-B Recombinant Mouse DNAJB6 Protein Pre-coupled Magnetic Beads HEK293
Rat DNAJB6-1902R Recombinant Rat DNAJB6 Protein Mammalian Cell His
Rat DNAJB6-1561R-B Recombinant Rat DNAJB6 Protein Pre-coupled Magnetic Beads HEK293
Rat DNAJB6-1561R Recombinant Rat DNAJB6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DNAJB6-1286R Recombinant Rhesus monkey DNAJB6 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DNAJB6-1111R Recombinant Rhesus Macaque DNAJB6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DNAJB6-1111R-B Recombinant Rhesus Macaque DNAJB6 Protein Pre-coupled Magnetic Beads HEK293
Chicken DNAJB6-1928C Recombinant Chicken DNAJB6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DNAJB6 involved in several pathways and played different roles in them. We selected most pathways DNAJB6 participated on our site, such as Cellular response to heat stress, Cellular responses to stress, Regulation of HSF1-mediated heat shock response, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cellular response to heat stressDNAJC7;C11orf73;HSBP1;PTGES3;NUP35;DNAJB6;HSPA7;HSBP1B;HSPA13
Cellular responses to stressHIST2H3C;CHMP4B;HIST4H4;PRDX3;HIF3A;HDAC6;RRAGA;CDKN2C;ATG9A
Regulation of HSF1-mediated heat shock responseHSPH1;HSPA12B;DNAJC7;DNAJC2;ST13;HSPA7;RPS19BP1;DNAJB6;BAG5

DNAJB6 has several biochemical functions, for example, ATPase activator activity, DNA binding, chaperone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJB6 itself. We selected most functions DNAJB6 had, and list some proteins which have the same functions with DNAJB6. You can find most of the proteins on our site.

Function Related Protein
ATPase activator activityDNAJB6;DNAJC19;TOR1AIP1;RAB4A;ATP1B2;TOR1AIP2;ATP1B3;ATP1B1;DNAJB1
DNA bindingZSCAN10;ZFP821;NUPR1;H2AFY;ZFP580;HIST1H2BG;ZNF75A;ZNF654;HMG20A
chaperone bindingTIMM44;DNAJB4;H2-KE2;C1orf182;TSC1;ERP29;TBCE;TBCD;BAK1
heat shock protein bindingTOMM34;DNAJA3A;CDC37L1;LIMK1;IRAK1;DNAJA2L;GPR37;DLST;DAXX
protein bindingZBTB16;VPS36;TLK2;ASCC1;UBA5;ABCD1;HACL1;PAIP2;APBB2
unfolded protein bindingCCT6A;PPIA;AIPL1;DNAJA3A;HSPA8;SRSF12;CCT6B;TOMM20;DNAJA1

DNAJB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJB6.

KRT18; MLF1; MLF2; DYSF; SGCG; BRMS1; HSPA8; UBA1

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