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Official Full Name DSN1 DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
Background Defects in kinetochore proteins often lead to aneuploidy and cancer. Mis12-Ktw1 is a conserved essential kinetochore protein family. Human Mis13 protein (c20orf172) is one of the several proteins that form Mis12-kinetochore complex and required for chromosome segregation. Mis13 protein also physically interacts with Blinkin/AF15q14 which is required for mitotic checkpoint and chromosome alignment. It is also required for condensin to accumulate at kinetochores.
Synonyms DSN1; DSN1, MIND kinetochore complex component, homolog (S. cerevisiae); C20orf172, chromosome 20 open reading frame 172; kinetochore-associated protein DSN1 homolog; dJ469A13.2; hKNL 3; kinetochore null 3 homolog (C. elegans); KNL3; MIS13; kinetochore null 3 homolog; hKNL-3; C20orf172; FLJ13346; MGC32987;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DSN1-1153H Recombinant Human DSN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DSN1-2145H Recombinant Human DSN1 Protein (1-356 aa), GST-tagged E.coli GST
    Mouse Dsn1-2664M Recombinant Mouse Dsn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human DSN1-539H Recombinant Human DSN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DSN1-6389H Recombinant Human DSN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DSN1-236HCL Recombinant Human DSN1 lysate HEK293 N/A
    Human DSN1-2717H Recombinant Human DSN1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human DSN1-2892H Recombinant Human DSN1 Protein, GST-tagged Wheat Germ GST
    Rhesus Macaque DSN1-1336R Recombinant Rhesus monkey DSN1 Protein, His-tagged Mammalian Cell His
    Chicken DSN1-3452C Recombinant Chicken DSN1 Mammalian Cell His

    DSN1 involved in several pathways and played different roles in them. We selected most pathways DSN1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell Cycle KAT5; MCM3; GINS1; HIST3H2BB; CTDNEP1B; TP53; MND1; NDE1; NSL1; SDCCAG8
    Cell Cycle, Mitotic NUPL2; MCPH1; KIF20A; LIN9; CCP110; CEP290; SGOL2; TMPO; BLZF1; ANKLE2
    Mitotic Metaphase and Anaphase ZW10; CENPK; CENPQ; CENPC1; TMPO; SPC24; SKA1; AHCTF1; INCENP; CENPP
    Mitotic Prometaphase DSN1; SKA2; B9D2; ERCC6L; NCAPD2; SGOL2; INCENP; SGOL1; CDCA5; MIS12
    RHO GTPase Effectors NF2A; ABI2; RHPN2; MKL1; CLIP1; KTN1; RTKN; WASF3; PRC1; WIPF2
    RHO GTPases Activate Formins DIAPH1; CLIP1; RCC2; CCDC99; ZWINT; FMNL1; ZW10; MIS12; RANGAP1B; RHOC

    DSN1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DSN1 itself. We selected most functions DSN1 had, and list some proteins which have the same functions with DSN1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding INHBB; RNF216; E2F6; MRPS16; DRD2; CRTC2; MOV10; TNFAIP1; CCDC87; PDE4DIP

    DSN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DSN1.

    ZWINT; MIS12; Casc5; Mis12; CBX5; Bub1; BUB1; Zwint; Dsn1

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