dtx3
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  • Official Full Name
  • deltex 3 homolog (Drosophila)
  • Background
  • DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
  • Synonyms
  • DTX3; deltex 3 homolog (Drosophila); protein deltex-3; Deltex3; DTX3_HUMAN; Protein deltex 3; RING finger protein 154; RNF154; mDTX3; mg310
Cat.#:DTX3-2907HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DTX3 Protein, GST-tagged
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Cat.#:DTX3-12192HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DTX3, His-tagged
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Cat.#:DTX3-4858MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DTX3 Protein
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Cat.#:DTX3-6793HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human DTX3 293 Cell Lysate
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Involved Pathway

DTX3 involved in several pathways and played different roles in them. We selected most pathways DTX3 participated on our site, such as Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Notch Signaling Pathway
MARK2; DTX3; DLA; LNX1; HER6; RBPJA; NOTCH1B; MIB1; MAML2; NUMB

Protein Function

DTX3 has several biochemical functions, for example, ligase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX3 itself. We selected most functions DTX3 had, and list some proteins which have the same functions with DTX3. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein RNF4; NEDD4; TNFAIP3; ZNRF2; RNF34; UBE1Y1; RNF123; TRIM50; BRAP; LTN1
Function protein binding
Related Protein SBDS; CLSTN1; EIF4EBP2; PRPS1; EIF2B3; KITLG; PPIL1; C19orf25; TTC37; RCOR3
Function zinc ion binding
Related Protein RNPEPL1; TRIM37; ZBBX; HRG; ZDHHC8B; MARCH3; APOBEC3H; NR4A1; DDX58; BTY

Interacting Protein

DTX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX3.
UBE2K; HIP2; UBE2L6; UBE2D1; UBE2E1; UBE2D3; UBE2H; UBE2D2; UBE2L3; XIAP; UBE2V1; ZDHHC17; UBE2DNL; UEVLD; RNF141; UBE2E3; UBE2W; UBE2E2

DTX3 Related Articles

Gatza, ML; Silva, GO; et al. An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer. NATURE GENETICS 46:1051-1059(2014).
Konoki, K; Onoda, T; et al. In Vitro Acylation of Okadaic Acid in the Presence of Various Bivalves' Extracts. MARINE DRUGS 11:300-315(2013).