DYRK1B Protein, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

DYRK1B

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DYRK1B

Official Full Name dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
Background The DYRK family includes several dual-specificity tyrosine-phosphorylated and regulated kinases capable of phosphorylating proteins at both tyrosine and serine/threonine residues. The DYRK family was identified based on homology to the yeast Yak1 and the
Synonyms DYRK1B; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B; dual specificity tyrosine-phosphorylation-regulated kinase 1B; minibrain related kinase; MIRK; mirk protein kinase; minibrain-related kinase
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Insect cells
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DYRK1B-22H Recombinant Human DYRK1B Protein, GST-tagged Insect cells GST
    Human DYRK1B-12237H Recombinant Human DYRK1B, GST-tagged E.coli GST
    Human DYRK1B-2983H Recombinant Human DYRK1B Protein, GST-tagged Insect Cell GST
    Human DYRK1B-2984H Recombinant Human DYRK1B Protein, GST-tagged Wheat Germ GST
    Human DYRK1B-6751HCL Recombinant Human DYRK1B 293 Cell Lysate HEK293 N/A
    Mouse DYRK1B-4922M Recombinant Mouse DYRK1B Protein Mammalian Cell His
    Rhesus Macaque DYRK1B-1364R Recombinant Rhesus monkey DYRK1B Protein, His-tagged Mammalian Cell His
    Zebrafish DYRK1B-7638Z Recombinant Zebrafish DYRK1B Mammalian Cell His

    DYRK1B involved in several pathways and played different roles in them. We selected most pathways DYRK1B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DYRK1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    DYRK1B has several biochemical functions, for example, ATP binding, protein binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DYRK1B itself. We selected most functions DYRK1B had, and list some proteins which have the same functions with DYRK1B. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding SHPK; SLK; ABCG2C; KIF21A; NWD1; GRK7B; KIF3C; ALK; BMPR1BB; DHX38
    protein binding AGPAT1; GLYAT; MED24; RUSC1; RPGRIP1; RAB7A; PML; BAD; NFKB2; NPAS2
    protein kinase activity PAN3; CAMKK1A; PRKAB1; HIPK2; DCLK3; PAK4; DYRK1AA; NEK1; SBK3; CCL5
    protein serine/threonine kinase activity DCLK1A; CAMKK1B; BMPR1BA; PLK3; DMPK; MARK3; PIM3; SYK; DAPK1; MOK
    protein serine/threonine/tyrosine kinase activity SGK1; CLK3; DSTYK; RPS6KA1; DYRK1B; CLK1; PRKCG; TNK2; DYRK4; DYRK1A
    protein tyrosine kinase activity FGFR3; ERBB3B; EPHB4B; KIT; KDRL; FGR; ERBB3A; CSK; MAP2K1; LYN
    transcription coactivator activity SCAND1; WNT3A; PARK7; LPIN3; RFXAP; SUPT3H; KAT5; ARNT; MTA1; MAML2

    DYRK1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYRK1B here. Most of them are supplied by our site. Hope this information will be useful for your research of DYRK1B.

    HNF1A; RANBP9; DCAF7; RB1; RBL1; TROAP; LZTS2

    Hickmott, J; et al. DYRK1B variant linked to autosomal dominant metabolic syndrome. CLINICAL GENETICS 87:30-31(2015).
    Foucourt, A; Hedou, D; et al. Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part II. MOLECULES 19:15411-15439(2014).

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