dyrk4
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  • Official Full Name
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
  • Background
  • Dual-specificity kinases, such as DYRK4, play key roles in cell proliferation, survival, and development (Zhang et al.,;2005 (PubMed 15607427)).
  • Synonyms
  • DYRK4; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; dual specificity tyrosine-phosphorylation-regulated kinase 4; Dual specificity tyrosine phosphorylation regulated kinase 4; EC 2.7.12.1; OTTHUMP00000238290; OTTHUMP00000238291; OTTHUMP00000238292
Cat.#:DYRK4-2992HTag:Flag
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human DYRK4 Protein, Flag-tagged
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Cat.#:DYRK4-2993HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DYRK4 Protein, GST-tagged
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Cat.#:DYRK4-12240HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DYRK4, His-tagged
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Cat.#:DYRK4-6749HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DYRK4 293 Cell Lysate
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Protein Function

DYRK4 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYRK4 itself. We selected most functions DYRK4 had, and list some proteins which have the same functions with DYRK4. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein HUNK; DDX51; ACSS1; SLC27A2; TP53; PPP2R4; SBK1; KIF18B; HKDC1; MYHC4
Function metal ion binding
Related Protein ZNRF2A; ECEL1; GM9524; RNF128A; CYP2J5; ZFC3H1; INSM2; ADAP2; HBB-BH1; SDHC
Function protein binding
Related Protein CCDC120; C1QTNF3; NDUFAF1; CSNK1E; NPBWR1; VPS52; THRA; MTAP; PGAP2; LDLR
Function protein serine/threonine kinase activity
Related Protein MAPK6; CDC42BPG; STK17A; STK16; MAPK13; NIM1K; NEK2; DAPK1; IKBKB; GRK1B
Function protein serine/threonine/tyrosine kinase activity
Related Protein ACVR2B; TNK2; TESK2; MAP2K2; RPS6KB1; CLK3; AURKB; DYRK1AA; DYRK1A; MAP2K1
Function protein tyrosine kinase activity
Related Protein KIAA1804; ALK; EPHB4A; SRC; TESK2; SYK; JAK2B; EPHA4B; FYN; ERBB3A

Interacting Protein

DYRK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYRK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYRK4.
DYRK2; MID1; HSP90AA1; HSP90AB1; PPP1CC; CUL3; CDIPT; ATP1A1; USP11; RCN1; YME1L1; WDR33; TECR

DYRK4 Related Articles

Schmitt, C; Miralinaghi, P; et al. Hydroxybenzothiophene Ketones Are Efficient Pre-mRNA Splicing Modulators Due to Dual Inhibition of Dyrk1A and Clk1/4. ACS MEDICINAL CHEMISTRY LETTERS 5:963-967(2014).
Barallobre, MJ; Perier, C; et al. DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. CELL DEATH & DISEASE 5:-(2014).