eef1a2
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  • Official Full Name
  • eukaryotic translation elongation factor 1 alpha 2
  • Background
  • This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
  • Synonyms
  • EEF1A2; eukaryotic translation elongation factor 1 alpha 2; HS1; STN; EF1A; STNL; EEF1AL; EF-1-alpha-2; elongation factor 1-alpha 2; statin-S1; eukaryotic elongation factor 1 A-2;
Cat.#:EEF1A2-3067HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EEF1A2 Protein, GST-tagged
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Cat.#:EEF1A2-12289HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EEF1A2, His-tagged
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Cat.#:EEF1A2-28465THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EEF1A2, T7 -tagged
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Cat.#:EEF1A2-3061HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EEF1A2, T7-tagged
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Cat.#:EEF1A2-4999MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EEF1A2 Protein
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Cat.#:EEF1A2-2014RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EEF1A2 Protein
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Cat.#:EEF1A2-3258CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EEF1A2
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Cat.#:EEF1A2-515ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EEF1A2
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Cat.#:EEF1A2-242HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human EEF1A2 lysate
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Involved Pathway

EEF1A2 involved in several pathways and played different roles in them. We selected most pathways EEF1A2 participated on our site, such as Eukaryotic Translation Elongation, Gene Expression, Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEF1A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Eukaryotic Translation Elongation
EEF1D; EEF1A1; EEF1A2; EEF1G; EEF1B2; EEF2; RPL35
Gene Expression
ZNF764; EIF2S1; POLR3H; RBB4L; ZNF680; JUNB; SUPT5H; GM3258; ZNF287; ZNF212
Legionellosis
EEF1A1; CASP8; BCL2L13; HSPA1B; IL12B; CLK1; NLRC4; TNF; IL6; HSPA1L
Metabolism of proteins
LMCD1; ARSI; EIF2B1; TFG; SEC61B; TIMM10; IGFBP6A; MGAT4B; ST6GALNAC2; CTSH
RNA transport
NUP88; WIBG; NUP85; EIF3EA; NXT1; EIF4BA; EIF2S3Y; EIF3HA; NUP210L; MAGOH
Translation
EEF1D; EEF1A2; EEF1G; APEH; EEF1B2; EIF2B1; EIF5
Translation Factors
EIF4EBP2; EIF2B1; EEF1G; EIF5A; EEF1B2; PAIP1; EIF1; EEF2B; EEF1A2; EEF1D

Protein Function

EEF1A2 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEF1A2 itself. We selected most functions EEF1A2 had, and list some proteins which have the same functions with EEF1A2. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein MFN1; RAB14L; SEPT4A; RAB43; RAP2C; RAB3AA; RHOJ; ARF4B; ATL2; IRGE4
Function GTPase activity
Related Protein TUBA3E; DIRAS3; RALBB; RAB7A; EEF2; RAC1; NUDT1; GNB1; GNAO1; RAB6C
Function protein binding
Related Protein KIAA1524; RPS16; RBFA; TMPRSS7; LIN7A; MED21; VAMP8; SCYL3; FCN2; TPD52L1
Function protein kinase binding
Related Protein ARHGEF7; AP2A2; CD3E; CDC42; EEF2; TCF7L2; TEX14; TRIM5; PARP1; TNIP2
Function translation elongation factor activity
Related Protein EEF1A1; EEF2B; EEF1A1L1; GFM1; TUFM; EEF2; EEF1B2; EEF1D; EEFSEC; EIF5A2
Function translation factor activity, RNA binding
Related Protein EEF1A2; CPEB1B; EIF4G2; CPEB4; EEF2K; EIF4G3; EIF4A1; PPP1R2P9; EIF4H; CPEB1A

Interacting Protein

EEF1A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEF1A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EEF1A2.
ABTB1; NFKB2; CHUK; TNFRSF1B; EEF1B2; VARS; EEF1D; MAP3K8; NFKB2; RELA; TRAF2; MAP3K1; TRADD; LRRK2; MAP3K3; TAB2; TRAF6; RIPK3

EEF1A2 Related Articles

Chen, CY; Fang, HY; et al. Sumoylation of eukaryotic elongation factor 2 is vital for protein stability and anti-apoptotic activity in lung adenocarcinoma cells. CANCER SCIENCE 102:1582-1589(2011).
Piazzi, M; Bavelloni, A; et al. eEF1A Phosphorylation in the Nucleus of Insulin-stimulated C2C12 Myoblasts SER53 IS A NOVEL SUBSTRATE FOR PROTEIN KINASE C beta I. MOLECULAR & CELLULAR PROTEOMICS 9:-(2010).