eef1d
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  • Official Full Name
  • eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
  • Background
  • This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.
  • Synonyms
  • EEF1D; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); elongation factor 1-delta; EF 1D; FLJ20897; Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EF 1 delta; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Eukaryotic translation elongation factor 1 delta; Guanine nucleotide exchange protein; EF-1D; FP1047
Cat.#:EEF1D-1205HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human EEF1D Protein, MYC/DDK-tagged
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Cat.#:EEF1D-3071HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EEF1D Protein, GST-tagged
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Cat.#:EEF1D-28466THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EEF1D, His-tagged
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Cat.#:EEF1D-3463HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EEF1D, His-tagged
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Cat.#:Eef1d-1396MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Eef1d protein, His & T7-tagged
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Cat.#:EEF1D-5001MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EEF1D Protein
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Cat.#:EEF1D-2015RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat EEF1D Protein
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Cat.#:EEF1D-479CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus EEF1D Protein, His-tagged
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Cat.#:EEF1D-531HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human EEF1D cell lysate
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Involved Pathway

EEF1D involved in several pathways and played different roles in them. We selected most pathways EEF1D participated on our site, such as Eukaryotic Translation Elongation, Gene Expression, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with EEF1D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Eukaryotic Translation Elongation
RPL35; EEF1G; EEF1D; EEF1A1; EEF1A2; EEF1B2; EEF2
Gene Expression
FKBP6; COX6B1; EEF1B2; ZNF224; POLR3G; ZNF221; NR2F1A; ZNF234; MTA3; NR2F1
Herpes simplex infection
CASP8; IRF7; OAS3; MHC1UEA; CCL2; HLA-C; TLR2; MCRS1; IRF3; SRSF5B
Metabolism of proteins
GRPEL2; PFDN6; SAMM50; TIMM9; MLEC; ADAMTSL3; IGFBP2A; B3GNT6; TOMM6; GALNTL2
Translation
EEF1G; EEF1B2; EIF2B1; APEH; EEF1A2; EIF5; EEF1D
Translation Factors
EEF1A2; EEF2B; EEF1B2; PAIP1; EEF1D; EIF4EBP2; EIF1; EIF2B1; EIF5A; EEF1G

Protein Function

EEF1D has several biochemical functions, for example, DNA binding, activating transcription factor binding, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EEF1D itself. We selected most functions EEF1D had, and list some proteins which have the same functions with EEF1D. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein PAX8; ZFAND5B; ORC6L; TAF11; DBX1; DDIT3; PHF5A; CEBPZ; H2AFB1; LHX2A
Function activating transcription factor binding
Related Protein GATA4; DGKQ; MEF2A; HDAC7A; MEF2C; PPARG; EEF1D; HDAC7; SMAD2; TAF9
Function heat shock protein binding
Related Protein HDAC2; KCNJ11; HSPA1B; DNAJA2L; PDXP; HSPA1L; IRAK1; DNAJB6; PPP5C; GM5506
Function protein binding
Related Protein KRT38; ZNF124; TSPYL4; BHLHE40; VEGFAA; TRAPPC3; KRT2; ARHGAP33; DLL4; SPANXC
Function signal transducer activity
Related Protein PLCD3; TAS2R110; PTGER1B; SLC20A1; PLCXD2; HTR1AA; TRAF3; GPR141; OLFCJ1; MRGPRA5
Function translation elongation factor activity
Related Protein EEF1A1A; EEF1A1B; EEF2; EEF2A.2; EEF1D; EFTUD1; EEF2B; EEF1DB; EEF1DA; EEF1E1
Function translation factor activity, RNA binding
Related Protein PPP1R2P9; CPEB4; EIF4G3; GTF2H2; EIF4E2; EIF2S2; EIF1; EEF1D; GTF2H3; EIF1AX

Interacting Protein

EEF1D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EEF1D here. Most of them are supplied by our site. Hope this information will be useful for your research of EEF1D.
SIAH1; TPT1; EEF1G; ERP27; EEF1G; ATG7