ENPP1
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Official Full Name
ectonucleotide pyrophosphatase/phosphodiesterase 1
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Overview
Ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) is a single-pass, type II transmembrane protein primarily involved in ATP hydrolysis at the plasma membrane. Targeting of ENPP1 to the basolateral cell surface relies on the presence of a carboxy- -
Synonyms
ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1; M6S1, NPPS, PDNP1; ectonucleotide pyrophosphatase/phosphodiesterase family member 1; PC 1; PCA1; E-NPP 1; Ly-41 antigen; alkaline phosphodiesterase 1; plasma-cell membrane glycoprotein 1; plasma-c;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|GST
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ENPP1-1414H | Recombinant Human ENPP1 protein, His-tagged | E.coli | His | Asp362~Trp518 (Accession # P22413) | |
Human | ENPP1-3320H | Recombinant Human ENPP1 Protein | Wheat Germ | N/A | ||
Human | ENPP1-3321H | Recombinant Human ENPP1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | ENPP1-6595HCL | Recombinant Human ENPP1 293 Cell Lysate | HEK293 | N/A | ||
Human | ENPP1-4318HF | Recombinant Full Length Human ENPP1 Protein | In Vitro Cell Free System | 290 amino acids | ||
Human | ENPP1-3365H | Recombinant Human ENPP1 protein, Myc/DDK-tagged | HEK293 | Myc/DDK | ||
Human | ENPP1-1024H | Recombinant Human ENPP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | ENPP1-1235H | Recombinant Human ENPP1 protein, His-tagged | HEK293 | His | Lys98-Asp925 | |
Human | ENPP1-4319HF | Recombinant Full Length Human ENPP1 Protein, GST-tagged | In Vitro Cell Free System | GST | 873 amino acids | |
Mouse | Enpp1-1415M | Recombinant Mouse Enpp1 protein, His & GST-tagged | E.coli | His/GST | Gly568~Asp789 | |
Mouse | Enpp1-78M | Recombinant Mouse Enpp1 protein, Myc/DDK-tagged | HEK293 | Myc/DDK | ||
Mouse | Enpp1-2831M | Recombinant Mouse Enpp1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Rat | ENPP1-2103R | Recombinant Rat ENPP1 Protein | Mammalian Cell | His | ||
Rat | Enpp1-1416R | Recombinant Rat Enpp1 protein, His & GST-tagged | E.coli | His/GST | Glu568~Ile793 (Accession # Q924C3) | |
Rat | ENPP1-1760R | Recombinant Rat ENPP1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | ENPP1-1760R-B | Recombinant Rat ENPP1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | ENPP1-3278Z | Recombinant Zebrafish ENPP1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ENPP1 Related Articles
- ENPP1 Related Research Area
ENPP1 involved in several pathways and played different roles in them. We selected most pathways ENPP1 participated on our site, such as Purine metabolism, Starch and sucrose metabolism, Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ENPP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Purine metabolism | POLR1B;NUDT5;GUK1;PKMA;POLR2F;NPR2;POLR2GL;PGM1;ADCY2B |
Starch and sucrose metabolism | AGL;HK2;TREH;GPI1;UGT1A7;UGT5G1;GYS2;GPIB;AMY2A5 |
Nicotinate and nicotinamide metabolism | AOX3L1;NT5C1B-RDH14;NMNAT1;NMNAT3;NT5C;NT5C3A;AOX4;NUDT12;NT5C3B |
Pantothenate and CoA biosynthesis | COASY;BCAT2;DPYD;PPCDC;VNN1;PANK2;DPYS;UPB1;AASDHPPT |
Metabolic pathways | ST3GAL2;NME4;AKR1B1;UQCRB;HADHB;CYP2C37;UGT1A1;ALOX5;NDUFB6 |
ENPP1 has several biochemical functions, for example, 3-phosphoadenosine 5-phosphosulfate binding, ATP binding, NADH pyrophosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ENPP1 itself. We selected most functions ENPP1 had, and list some proteins which have the same functions with ENPP1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
3-phosphoadenosine 5-phosphosulfate binding | HS3ST5;CHST15;GAL3ST4;ENPP1;CHST12 |
ATP binding | ERN2;ACSL1;PAPD4;RARS;UBE2C;UBE2J2;CARS;AMHR2;KIF2A |
NADH pyrophosphatase activity | ENPP1;NUDT12 |
calcium ion binding | NOTCH3;FREM1A;PCDH2AB9;STIM1;PLCB3;CLGN;MYL13;RASGRP4;NKD1 |
insulin receptor binding | IGF1R;SNX2;IGF1;DOK4;DOK3;INS1;FRS2B;DOK6;IRS2 |
nucleic acid binding | WT1B;ZFP828;ZFR;ZNF45L;RBM14A;ZFP710;ZFP385C;TBK1;ZFP13 |
nucleoside-triphosphate diphosphatase activity | ENPP1;DCTPP1 |
nucleotide diphosphatase activity | ENPP1;ENPP2 |
phosphodiesterase I activity | ENPP1;ENPP2;APEX1;FAN1 |
polysaccharide binding | ENDOU;VTNA;TINAG;CLEC4G;SUSD2;AGL;C8orf84;MBL1;ENPP1 |
protein binding | RBM17;MYCBP;GDPD5;PELI2;ARL16;EXO1;RHOBTB3;RAB9A;RNF2 |
protein homodimerization activity | HNF1B;CD200;CHMP3;EFR3A;FAP;HPGD;CACYBP;CHMP1A;ADAM10 |
scavenger receptor activity | CXCL16;LGALS3BPB;ACKR4;LOXL4;C8orf84;PRG4A;VTN;CD5L;ENPP1 |
zinc ion binding | ZDHHC11;RNF166;NR4A2;APOBEC3C;ANPEPB;YAF2;NR5A1;LIMCH1B;MSL2 |
ENPP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ENPP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ENPP1.
INSR; Dlg4; SQSTM1
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