errfi1
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  • Official Full Name
  • ERBB receptor feedback inhibitor 1
  • Background
  • ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 (PubMed 7641805)).;It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and;mediates cell signaling (Makkinje et al., 2000 (PubMed 10749885); Fiorentino et al., 2000 (PubMed 11003669)).
  • Synonyms
  • ERRFI1; ERBB receptor feedback inhibitor 1; GENE 33; MIG 6; RALT; mitogen-inducible gene 6 protein; receptor-associated late transducer; MIG6; MIG-6; GENE-33
Cat.#:ERRFI1-3491HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ERRFI1 Protein, GST-tagged
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Cat.#:ERRFI1-2145RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ERRFI1 Protein
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Cat.#:ERRFI1-1498RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ERRFI1 Protein, His-tagged
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Cat.#:ERRFI1-5423ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ERRFI1
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Cat.#:ERRFI1-6542HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ERRFI1 293 Cell Lysate
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Involved Pathway

ERRFI1 involved in several pathways and played different roles in them. We selected most pathways ERRFI1 participated on our site, such as EGFR1 Signaling Pathway, Signaling Pathways in Glioblastoma, which may be useful for your reference. Also, other proteins which involved in the same pathway with ERRFI1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
EGFR1 Signaling Pathway
KRT17; AP2A1; RGS16; PITPNA; ELF3; REPS1; EPS8; RALBB; TNK2; ABI1B
Signaling Pathways in Glioblastoma
ERRFI1

Protein Function

ERRFI1 has several biochemical functions, for example, GTPase activator activity, SH3 domain binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ERRFI1 itself. We selected most functions ERRFI1 had, and list some proteins which have the same functions with ERRFI1. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activator activity
Related Protein HTR2B; TBC1D10C; AXIN2; DAB2IPB; SGSM2; ARHGAP6; TBC1D3C; DOCK1; GIT2A; CHN2
Function SH3 domain binding
Related Protein ARHGAP27; MAPT; RAD9A; INPPL1; SH3BP2; CBL; ELMO2; ELMO1; SIRPA; PARK2
Function protein binding
Related Protein LGALS9C; SH2B2; NPRL2; CNOT2; PDE6G; RAB13; AP1B1; ALDOB; KARS; CLPX
Function protein kinase binding
Related Protein NPM1; MAP2K7; PRKAG2; FAM83D; CCNE2; MAP3K13; KIF14; PAK2; GSTP2; LSM2
Function small GTPase binding
Related Protein FLNA; RCC2; TSC2; FGD6; FGD4; PEX5L; ERRFI1; RNF152; FGD1; FGD3

Interacting Protein

ERRFI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ERRFI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ERRFI1.
GRB2; EGFR; SFN; ERBB2

ERRFI1 Related Articles

Liu, J; Cho, SN; et al. ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis. CELL REPORTS 10:1599-1613(2015).
Chen, YC; Colvin, ES; et al. Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes. DIABETOLOGIA 57:2066-2075(2014).