|Official Full Name||v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)|
|Background||This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded;protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is;located on the X chromosome. Alternative splicing results in multiple transcript variants.|
|Synonyms||ETS2; v-ets erythroblastosis virus E26 oncogene homolog 2 (avian); v ets avian erythroblastosis virus E26 oncogene homolog 2; protein C-ets-2; C ets 2 protein; ETS2_HUMAN; ETS2IT1; Oncogene ETS2; v ets avian erythroblastosis virus E2 oncogene homolog 2; V ets erythroblastosis virus E26 oncogene homolog 2; oncogene ETS-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ETS2 involved in several pathways and played different roles in them. We selected most pathways ETS2 participated on our site, such as Ras signaling pathway, Dorso-ventral axis formation, HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with ETS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ras signaling pathway||FGF8; PLCG2; RAC3; PDGFA; FGF4; RAC2; RASGRF2; RHOA; ARF6; NF1|
|Dorso-ventral axis formation||MAPK1; SOS1; MAP2K1; NOTCH1; CPEB2; MAPK3; PIWIL2; ETV6; SPIRE2; GRB2B|
|HTLV-I infection||MYB; VAC14; VDAC3; HLA-C; WNT7A; RELA; TLN1; HLA-DRA; VDAC2; HLA-DPB1|
ETS2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ETS2 itself. We selected most functions ETS2 had, and list some proteins which have the same functions with ETS2. You can find most of the proteins on our site.
|DNA binding||ISL1L; ZNF483; THAP6; ATM; PCXA; GON4L; VEZF1; DEM1; RTEL1; ZFP367|
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||RFX6; ETV2; TLX1; IFI203; HSF1; ZNF543; PAXBP1; RFX8; NR6A1; T|
|glucocorticoid receptor binding||STAT5B; STAT3; NR4A2; NRIP1; EP300; GRIP1; YWHAH; CEBPB; FKBP4; ETS2|
|protein binding||ERCC5; TTC19; TMUB2; FGF13; CXCL14; IL4R; IL18R1; C9orf142; RBM39; PIDD1|
|transcription factor activity, sequence-specific DNA binding||UBP1; TEFA; ZNF286A; POU6F2; ZNF187; ZBTB48; ATF6; RXRAA; ARNTL1A; GLI3|
|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding||ZNF148; BTG2; NFIL3-5; RCOR1; GATA3; E2F8; YY1; BATF3; ZFPM2; NKX6|
ETS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ETS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ETS2.
RFWD2; CDK10; TWIST1; TWIST2; RFWD2; ZFYVE9; sSL2; htrA; clpB; q7clb3_yerpe; proA; phnI; ubiG; gcvP; raf1_human_gene