fbxo6
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  • Official Full Name
  • F-box protein 6
  • Background
  • This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
  • Synonyms
  • FBXO6; F-box protein 6; F box only protein 6; F-box only protein 6; FBG2; FBS2; FBX6; Fbx6b; F-box protein FBG2; F-box protein Fbx6; F-box/G-domain protein 2; F-box protein that recognizes sugar chains 2
Cat.#:FBXO6-3959HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBXO6 Protein, GST-tagged
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Cat.#:FBXO6-12804HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBXO6, GST-tagged
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Cat.#:FBXO6-214HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human F-box protein 6, His-tagged
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Cat.#:FBXO6-5760MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FBXO6 Protein
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Cat.#:FBXO6-2299RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FBXO6 Protein
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Cat.#:FBXO6-6289HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FBXO6 293 Cell Lysate
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Involved Pathway

FBXO6 involved in several pathways and played different roles in them. We selected most pathways FBXO6 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Protein processing in endoplasmic reticulum
BAXA; DNAJC5GB; UBE2G1B; PDIA6; PARK2; RPN1; ERO1LB; SSR4; HSP90AA1.1; NSFL1C

Protein Function

FBXO6 has several biochemical functions, for example, carbohydrate binding, glycoprotein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO6 itself. We selected most functions FBXO6 had, and list some proteins which have the same functions with FBXO6. You can find most of the proteins on our site.
Function
Related Protein
Function carbohydrate binding
Related Protein NPTX2; HBL3; ILLR3; CD209C; CLEC2B; CANX; EMC7; MAG; GCKR; CD69
Function glycoprotein binding
Related Protein CALR; B2M; SDCBP; FBXO27; BBC3; TFRC; DNAJC5; SERPINA1; TFR2; ERBB2
Function protein binding
Related Protein UBA3; THEM5; SENP5; FAM64A; KLC3; BLNK; AHCYL1; SAMHD1; SCRN1; CTSH
Function ubiquitin protein ligase activity
Related Protein RNF6; MED7; RNF121; ZNRF1; CDC34A; NEDD4L; RNF4; RNF111; ITCH; CCNB1IP1

Interacting Protein

FBXO6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO6.
HSP90AB1; CUL1; ORC4; env