FBXO6 Protein, F-box protein 6


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Official Full Name F-box protein 6
Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle.
Synonyms FBXO6; F-box protein 6; F box only protein 6; F-box only protein 6; FBG2; FBS2; FBX6; Fbx6b; F-box protein FBG2; F-box protein Fbx6; F-box/G-domain protein 2; F-box protein that recognizes sugar chains 2
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FBXO6-12804H Recombinant Human FBXO6, GST-tagged E.coli GST
    Human FBXO6-214H Recombinant Human F-box protein 6, His-tagged E.coli His
    Human FBXO6-3959H Recombinant Human FBXO6 Protein, GST-tagged Wheat Germ GST
    Human FBXO6-6289HCL Recombinant Human FBXO6 293 Cell Lysate HEK293 N/A
    Mouse FBXO6-5760M Recombinant Mouse FBXO6 Protein Mammalian Cell His
    Rat FBXO6-2299R Recombinant Rat FBXO6 Protein Mammalian Cell His

    FBXO6 involved in several pathways and played different roles in them. We selected most pathways FBXO6 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum SEL1L2; EIF2AK1; ERP29; UBE2D1A; SEL1L; WFS1; CUL1B; RNF185; SEC13; HSPA1A

    FBXO6 has several biochemical functions, for example, carbohydrate binding, glycoprotein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO6 itself. We selected most functions FBXO6 had, and list some proteins which have the same functions with FBXO6. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding LGALS3L; Mgl2; CANX; CLEC9A; LMAN1L; FBXO2; CLEC4E; CLEC4A2; Siglec1; SIGLEC7
    glycoprotein binding TGFB1; FOXRED2; CANX; IDE; TFR2; FBXO6; FBXO27; ERLEC1; CSNK1D; PLAT
    protein binding HSD3B7; THAP10; ITGAV; SPG21; HMOX1; TDGF1; GP1BA; EPB41B; KRT83; HTR1A
    ubiquitin protein ligase activity UBE2U; BRAP; PARK2; UBR1; MSL2A; ZSWIM2; RNF139; PRPF19; RABGEF1; CDC34A

    FBXO6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO6 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO6.

    HSP90AB1; CUL1; ORC4; env

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