Recombinant Human FBXO6 Protein, GST-tagged

• Cat.No.: FBXO6-3959H
• Product Overview: Human FBXO6 full-length ORF ( AAH20880.1, 1 a.a. - 293 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 57.97 kDa
• AA Sequence: MDAPHSKAALDSINELPENILLELF THVPARQLLLNCRLVCSLWRDLIDL MTLWKRKCLREGFITKDWDQPVADW KIFYFLRSLHRNLLRNPCAEEDMFA WQIDFNGGDRWKVESLPGAHGTDFP DPKVKKYFVTSYEMCLKSQLVDLVA EGYWEELLDTFRPDIVVKDWFAARA DCGCTYQLKVQLASADYFVLASFEP PPVTIQQWNNATWTEVSYTFSDYPR GVRYILFQHGGRDTQYWAGWYGPRV TNSSIVVSPKMTRNQASSEAQPGQK HGQEEAAQSPYRAVVQIF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXO6 F-box protein 6 [ Homo sapiens ]
• Official Symbol: FBXO6
• Synonyms: FBXO6; F-box protein 6; F box only protein 6; F-box only protein 6; FBG2; FBS2; FBX6; Fbx6b; F-box protein FBG2; F-box protein Fbx6; F-box/G-domain protein 2; F-box protein that recognizes sugar chains 2
• Gene ID: 26270
• mRNA Refseq: NM_018438
• Protein Refseq: NP_060908
• MIM: 605647
• UniProt ID: Q9NRD1