fcgr2c
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  • Official Full Name
  • FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) [ Homo sapiens ]
  • Background
  • This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.
  • Synonyms
  • Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene); 15626; low affinity immunoglobulin gamma Fc region receptor II-c; fc-gamma-RIIc; IgG Fc receptor II-c; Fc gamma receptor IIC; immunoglobulin G Fc receptor II-c; CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC
Cat.#:FCGR2C-12821HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FCGR2C, GST-tagged
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Involved Pathway

FCGR2C involved in several pathways and played different roles in them. We selected most pathways FCGR2C participated on our site, such as Phagosome, Osteoclast differentiation, Leishmaniasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
VAMP3; RAB5B; HLA-E; TUBA3D; BLB2; RAC1; ATP6V0B; TUBB1; NOX3; ITGAV
Osteoclast differentiation
SFPI1; NCF1; MAP3K14; GAB2; SIRPA; PIK3CB; PPP3R2; BTK; PIK3CD; FCGR3A
Leishmaniasis
HLA-DQA2; MAPK3; PTGS2; HLA-DMA; NCF4; MYD88; IL1A; HLA-DRB1; FCGR1A; STAT1
Staphylococcus aureus infection
C1S; FGG; C3; HLA-DMA; FCGR1; DSG1A; Itgam&Itgb2; FCGR1A; C5; C1R
Tuberculosis
CASP8; ITGB2L; IL18; IFNA4; Il23a; Il12b; HLA-DRB5; IL12B; CALML3; FCGR3; CD209A

Protein Function

FCGR2C has several biochemical functions, for example, IgG binding, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR2C itself. We selected most functions FCGR2C had, and list some proteins which have the same functions with FCGR2C. You can find most of the proteins on our site.
Function
Related Protein
Function IgG binding
Related Protein FCGR2B; FCGR2C; FCGR2A; FCER1G; FCGR1A; FCGR3B; FCGR1; UMOD; FCGR1B; cgr2b
Function protein binding
Related Protein SERPINC1; MORF4L2; APOL1; NTM; ADH1A; CARS; RBFOX1; CHTOP; ERRFI1; RBMY1A1
Function transmembrane signaling receptor activity
Related Protein PTH1RB; TLR9; NCR2; Fzd4; GHRHR2; CD4; OR4C13; EMR4; IGSF6; CLEC4A