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FCGR2C

  • Official Full Name

    FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) [ Homo sapiens ]

  • Overview

    This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.
  • Synonyms

    Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene); 15626; low affinity immunoglobulin gamma Fc region receptor II-c; fc-gamma-RIIc; IgG Fc receptor II-c; Fc gamma receptor IIC; immunoglobulin G Fc receptor II-c; CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FCGR2C-12821H Recombinant Human FCGR2C, GST-tagged E.coli GST C-term-70a.a.
Homo sapiens (Human) RFL32664HF Recombinant Full Length Human Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C(Fcgr2C) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (43-323)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FCGR2C Related Research Area

FCGR2C involved in several pathways and played different roles in them. We selected most pathways FCGR2C participated on our site, such as Phagosome, Osteoclast differentiation, Leishmaniasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeVAMP3;CD36;MHC2DAB;HLA-DPA1;SEC61G;ITGB3;CTSLA;MHC2DEB;BLB2
Osteoclast differentiationLILRB2;LILRB4;FCGR2A;TAB2;IFNAR2;FCGR1;GAB2;MAP3K14;TRAF6
LeishmaniasisFCGR3B;HLA-DQA1;TRAF6;TLR2;TLR4;TGFB3;FCGR1A;TAB2;ITGB2
Staphylococcus aureus infectionFPR3;MBL1;FPR2;Itgam&Itgb2;DSG1A;HLA-DRB1;DSG1C;DSG1;C4A
TuberculosisFCGR2A;HLA-DMA;CASP9;HSPA9;Il23a;SYK;CD74;IL10RA;TGFB2

FCGR2C has several biochemical functions, for example, IgG binding, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR2C itself. We selected most functions FCGR2C had, and list some proteins which have the same functions with FCGR2C. You can find most of the proteins on our site.

Function Related Protein
IgG bindingFCGR2C;CD247L;FCGR3B;FCGR1B;FCER1G;FCGR1A;FCGR1;PIP;FCGR2A
protein bindingDCDC2B;CSK;TJP2;NUP50;IFT20;RABAC1;PLEKHG6;GGNBP2;RNF115
transmembrane signaling receptor activityICAM1;CD72;EMR4;GLP1R;KIR2DL4;NRXN3;GHRHR2;LGR6;FZD3B

FCGR2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGR2C here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGR2C.

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