foxd3
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  • Official Full Name
  • forkhead box D3
  • Background
  • The FOXD3 Antibody recognizes human FOXD3 also known as Forkhead box protein D3 and HNF3/FH transcription factor genesis. FOXD3 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain, predicted molecul
  • Synonyms
  • FOXD3; forkhead box D3; forkhead box protein D3; Genesis; HFH2; HNF3/FH transcription factor genesis; AIS1; VAMAS2
Cat.#:FOXD3-1062HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human FOXD3
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Cat.#:FOXD3-144HTag:Arg
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FOXD3 protein, Arginine-tagged
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Cat.#:FOXD3-1741RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FOXD3 Protein, His-tagged
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Cat.#:FOXD3-6510CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FOXD3
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Cat.#:FOXD3-8881ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FOXD3
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Involved Pathway

FOXD3 involved in several pathways and played different roles in them. We selected most pathways FOXD3 participated on our site, such as Developmental Biology, Neural Crest Differentiation, POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Developmental Biology
ARPC1B; KALRN; MED16; BOC; NTN1A; DUSP9; CDON; SCN3A; MED21; PITPNA
Neural Crest Differentiation
DLX5; MYB; ASCL1; HOXA1; MIA; OLIG2; MBP; SOX10; SOX5; OLIG1
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
NR6A1; TDGF1; FOXD3
Transcriptional regulation of pluripotent stem cells
SALL4; TDGF1; PRDM14; HIF3A; NR6A1; POU5F3; FOXD3; NR5A1; LIN28A
Wnt Signaling Pathway and Pluripotency
FBXW2; ZBTB33; FOXD3; LRRK2; PPM1J

Protein Function

FOXD3 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXD3 itself. We selected most functions FOXD3 had, and list some proteins which have the same functions with FOXD3. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II regulatory region sequence-specific DNA binding
Related Protein PRDM15; PURB; E4F1; GATA2; AASS; PRDM12B; HOXD9; ATF1; SUV39H1; BARX1
Function protein binding
Related Protein C9orf78; RSAD2; WDR24; NAA11; MPZL2B; IKBKB; NTHL1; PXMP2; DNAJC7; BRD7
Function transcription factor activity, sequence-specific DNA binding
Related Protein JUNBB; ZNF8; RORA; FOXG1C; HOXC8A; ZNF192; FOXI3A; SALL2; DMRT1; BACH1A
Function transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
Related Protein AEBP1; SATB1; HMX1; ZNF350; ETV7; MNT; ARHGAP35; PCGF6; KLF12; FEZF2

Interacting Protein

FOXD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXD3.
POU5F1

FOXD3 Related Articles

Guo, RJ; Wu, QH; et al. Description of the CD133(+) subpopulation of the human ovarian cancer cell line OVCAR3. ONCOLOGY REPORTS 25:141-146(2011).
Gilbert, SF; Bender, G; et al. The contribution of neural crest cells to the nuchal bone and plastron of the turtle shell. INTEGRATIVE AND COMPARATIVE BIOLOGY 47:401-408(2007).