gbp1
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  • Official Full Name
  • guanylate binding protein 1, interferon-inducible
  • Background
  • Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3.
  • Synonyms
  • GBP1; guanylate binding protein 1, interferon-inducible; guanylate binding protein 1, interferon inducible, 67kDa; interferon-induced guanylate-binding protein 1; GBP-1; huGBP-1; GTP-binding protein 1; guanine nucleotide-binding protein 1; guanylate bindi
Cat.#:GBP1-1324HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human GBP1 Protein, MYC/DDK-tagged
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Cat.#:GBP1-4776HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GBP1 Protein, GST-tagged
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Cat.#:GBP1-13180HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GBP1, GST-tagged
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Cat.#:GBP1-28991THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human GBP1
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Cat.#:GBP1-53HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human GBP1 protein, His-tagged
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Cat.#:GBP1-6940HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human GBP1, His tagged
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Cat.#:GBP1-492ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GBP1
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Cat.#:GBP1-1686HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human GBP1 cell lysate
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Involved Pathway

GBP1 involved in several pathways and played different roles in them. We selected most pathways GBP1 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine Signaling in Immune system
TRIM29; ISG20; IFI6; DUSP9; IFITM3; EIF4E3; SPNA1; PELI3; PEBP1; DUSP7
Immune System
ISG20; STUB1; CASP2; CASP4; RAP1GAP2; AP1G1; Siglece; CD200R3; KPNA4; SUGT1
Interferon Signaling
GBP6; HLA-DQB2; FCGR1B; EIF4E3; TRIM5; OASL; TRIM10; TRIM14; SAMHD1; GBP5
Interferon gamma signaling
GBP6; GBP1; TRIM2; TRIM3; GBP5; TRIM38; FCGR1B; TRIM48; TRIM8; IFI30
Type II interferon signaling (IFNG)
REG1A; GBP1; IFI6; Ifna; IFIT2

Protein Function

GBP1 has several biochemical functions, for example, GTP binding, GTPase activity, Hsp90 protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GBP1 itself. We selected most functions GBP1 had, and list some proteins which have the same functions with GBP1. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein GTPBP5; RASL11B; RNGTT; GNAT3; RAB3DA; GTPBP8; GNA13B; ARL15A; GSPT2; SEPT8A
Function GTPase activity
Related Protein RAB11A; RAB24; RAB12; RRAS2; RAP1GAP; ARL8B; SEPT5; RAB9A; EEF2A.2; RAB3C
Function Hsp90 protein binding
Related Protein UNC45B; USP19; PPID; CSNK2A1; ERN1; RPS3; CDC37; EIF2AK3; GBP1; PPEF2
Function actin binding
Related Protein ESPN; MYO9B; XIRP2; MYBPC3; GSNA; SCINLB; CAP2; MED28; ENC1; WASB
Function cytokine binding
Related Protein CSF1R; CXCR4; GBP1; CRLF1; IL17F; LIFR; ELANE; PARK7; IFNGR1; NOG
Function enzyme binding
Related Protein HSPA2; TULP3; TARBP2; THRB; PRKCD; SCN5A; GOLPH3; AXIN1; RPA3; P4HB
Function identical protein binding
Related Protein SMAD1; GOT2; MBIP; KCNRG; TPRG1L; BLOC1S6; EID3; KHDC1B; LDHA; ACTN2
Function protein binding
Related Protein DLL1; SPINK2; RIPK3; SPRYD7; TNKS; RHOV; NLGN3; PRPF40A; KAL1; EIF2B2
Function spectrin binding
Related Protein CAMSAP1L1; GBP1; ANK1; SPTAN1; KIF3A; PTPRN; USH1G; MYO7A; EPB49; CAMSAP1

Interacting Protein

GBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBP1.
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GBP1 Related Gene Family

Cytokines