GBP4
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Official Full Name
guanylate binding protein 4
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Overview
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005;(PubMed 16108726)). -
Synonyms
GBP4; guanylate binding protein 4; guanylate-binding protein 4; Mpa2; GBP 4; GBP-4; GBP4_HUMAN; GTP binding protein 4; GTP-binding protein 4; Guanine nucleotide binding protein 4; Guanine nucleotide-binding protein 4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- C
- Myc
- DDK
- GST
- His
- His|T7
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | GBP4-1777H | Recombinant Human GBP4 protein, His & T7-tagged | E.coli | His/T7 | Met1~Lys292 (Accession # Q96PP9) |
|
| Human | GBP4-13182H | Recombinant Human GBP4, GST-tagged | E.coli | GST | 291-640a.a. | |
| Human | GBP4-5998HCL | Recombinant Human GBP4 293 Cell Lysate | HEK293 | N/A |
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| Human | GBP4-4779H | Recombinant Human GBP4 Protein, GST-tagged | Wheat Germ | GST |
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| Human | GBP4-3986H | Recombinant Human GBP4 protein, His-tagged | E.coli | His | 291-640 aa | |
| Human | GBP4-294H | Recombinant Human GBP4 Protein, MYC/DDK-tagged, C13 and N15-labeled | HEK293 | C-Myc/DDK |
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| Human | GBP4-5526HF | Recombinant Full Length Human GBP4 Protein, GST-tagged | In Vitro Cell Free System | GST | 640 amino acids |
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| Human | GBP4-3655H | Recombinant Human GBP4 Protein (Met1-Lys292), N-His tagged | E.coli | N-His | Met1-Lys292 |
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| Mouse | Gbp4-1778M | Recombinant Mouse Gbp4 protein, His & T7-tagged | E.coli | His/T7 | Met1~Cys304 (Accession # Q61107) |
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| Rat | Gbp4-1779R | Recombinant Rat Gbp4 protein, His & T7-tagged | E.coli | His/T7 | Met1~Cys304 (Accession # D3ZQL3) |
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| Zebrafish | GBP4-5306Z | Recombinant Zebrafish GBP4 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
GBP4 involved in several pathways and played different roles in them. We selected most pathways GBP4 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine Signaling in Immune system | TRIM17;IFI30;JAK1;GHRB;IL1RN;PELI2;EIF4G2A;FGF18B;GBP5 |
| Immune System | BFB;MB21D1;IRF4;TNFRSF13C;FBXO44;AF251705;MX2;NOD1;ASB9 |
| Interferon Signaling | TRIM5;GBP6;IFIT14;IFI35;SAMHD1;IRF2;XAF1;IFIT11;GBP4 |
| Interferon gamma signaling | TRIM29;GBP1;TRIM5;TRIM14;FCGR1B;TRIM10;IRF4;GBP2;TRIM3 |
GBP4 has several biochemical functions, for example, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GBP4 itself. We selected most functions GBP4 had, and list some proteins which have the same functions with GBP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | RALAB;RAP1B;RAC3A;MXB;GMPPB;RRAGCA;ARL4A;MFN1B;RAB6C |
| GTPase activity | RRAGD;GNA15.4;RASD2;EEF1A1A;RAB7L1;DNM1L;ARL2;ATL3;ARL4D |
GBP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBP4.
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