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GBP6

Official Full Name

guanylate binding protein family, member 6
Overview

Guanylate-binding proteins, such as GBP6, are induced by interferon and hydrolyze GTP to both GDP and GMP (Olszewski et;al., 2006 (PubMed 16689661)).
Synonyms

GBP6; guanylate binding protein family, member 6; guanylate-binding protein 6; DKFZp686G0786; GBP-6; GTP-binding protein 6; guanine nucleotide-binding protein 6; FLJ39135;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GBP6-1257H	Recombinant Human GBP6 protein, His & T7-tagged	E.coli	His/T7	Ser35~Arg277 (Accession # Q6ZN66)	Inquiry
Human	GBP6-1144H	Recombinant Human GBP6	Mammalian Cell	His		Inquiry
Human	GBP6-13184H	Recombinant Human GBP6, GST-tagged	E.coli	GST	530-633a.a.	$319 / 25ug
Human	GBP6-289HCL	Recombinant Human GBP6 lysate	HEK293	N/A		Inquiry
Human	GBP6-5155HF	Recombinant Full Length Human GBP6 Protein, GST-tagged	In Vitro Cell Free System	GST	633 amino acids	Inquiry
Human	GBP6-3020H-B	Recombinant Human GBP6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	GBP6-3020H	Recombinant Human GBP6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	GBP6-4781H	Recombinant Human GBP6 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GBP6-1319H	Recombinant Human GBP6 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	GBP6-2176H	Recombinant Human GBP6 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GBP6 involved in several pathways and played different roles in them. We selected most pathways GBP6 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GBP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine Signaling in Immune system	ADAR;NOD1;FGF8B;TRIM48;PELI3;HAVCR2;TNFSF13B;PAQR3A;EDARADD
Immune System	HAVCR2;TNIP2;CD226;CSHL1;ACTR2B;PPIAL4A;MYO1C;LRRC41;MYO9B
Interferon Signaling	BST2;ARIH1L;EIF4G2;TRIM2;USP18;TRIM17;ADAR;IFIT8;ARIH1
Interferon gamma signaling	OASL;TRIM5;HLA-DQB2;IRF6;TRIM62;IRF4;TRIM46;TRIM2;TRIM38

GBP6 has several biochemical functions, for example, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GBP6 itself. We selected most functions GBP6 had, and list some proteins which have the same functions with GBP6. You can find most of the proteins on our site.

Function	Related Protein
GTP binding	TUBA4A;RAB14L;RAB28;RAB18A;RAB5C;RAB4A;RAB22A;SEPT4A;TUBG1
GTPase activity	GIMAP7;TUBB2;RAB6B;RAB3AB;RAB7L1;RHOU;RAB1B;TUBA3C;RRAGCB

GBP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GBP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of GBP6.