Recombinant Human GBP6, GST-tagged

• Cat.No.: GBP6-13184H
• Product Overview: Recombinant Human GBP6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 530-633a.a.
• Description: This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GBP6 guanylate binding protein family, member 6 [ Homo sapiens ]
• Official Symbol: GBP6
• Synonyms: GBP6; guanylate binding protein family, member 6; guanylate-binding protein 6; DKFZp686G0786; GBP-6; GTP-binding protein 6; guanine nucleotide-binding protein 6; FLJ39135
• Gene ID: 163351
• mRNA Refseq: NM_198460
• Protein Refseq: NP_940862
• MIM: 612467
• UniProt ID: Q6ZN66
• Chromosome Location: 1p22
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding