gdap1
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  • Official Full Name
  • ganglioside-induced differentiation-associated protein 1
  • Background
  • This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms have been identified for this gene.
  • Synonyms
  • GDAP1; ganglioside-induced differentiation-associated protein 1; Charcot Marie Tooth neuropathy 4A , CMT4A; CMT4; Ganglioside induced differentiation associated protein 1; GDAP1_HUMAN; OTTHUMP00000226874; OTTHUMP00000226875; Charcot-Marie-Tooth neuropathy 4A; ganglioside differentiation associated protein 1; CMT4A; CMTRIA
Cat.#:GDAP1-4811HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GDAP1 Protein, GST-tagged
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Cat.#:GDAP1-6278MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GDAP1 Protein
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Cat.#:GDAP1-2841ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GDAP1
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Cat.#:GDAP1-5974HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GDAP1 293 Cell Lysate
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Protein Function

GDAP1 has several biochemical functions, for example, glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GDAP1 itself. We selected most functions GDAP1 had, and list some proteins which have the same functions with GDAP1. You can find most of the proteins on our site.
Function
Related Protein
Function glutathione transferase activity
Related Protein GSTT2B; GSTM6; GSTAL; GSTM2; GSTM; GSTT4; GSTA; GSTM7; GSTO1; GRX2

Interacting Protein

GDAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDAP1.
Prkaa1; Tmed10

GDAP1 Related Articles

Hsu, AK; Rosow, DE; et al. Familial congenital bilateral vocal fold paralysis: A novel gene translocation. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY 79:323-327(2015).
Del Amo, VL; Seco-Cervera, M; et al. Mitochondrial defects and neuromuscular degeneration caused by altered expression of Drosophila Gdap1: implications for the Charcot-Marie-Tooth neuropathy. HUMAN MOLECULAR GENETICS 24:21-36(2015).