ggt5
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  • Official Full Name
  • gamma-glutamyltransferase 5
  • Background
  • This gene is a member of a gene family that encodes gamma-glutamyl transpeptidase enzymes. This enzyme consists of a heavy and a light chain, and is able to hydrolyze the gamma-glutamyl moiety of glutathione. It converts leukotriene C4 to leukotriene D4, however, it doesnt convert synthetic substrates that are commonly used to assay gamma-glutamyl transpeptidase. Three transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • GGT5; gamma-glutamyltransferase 5; gamma glutamyltransferase like activity 1 , GGTLA1; GGT REL; DKFZP566O011; Gamma glutamyl transpeptidase related enzyme; Gamma glutamyltranspeptidase 5; GGT 5; gamma-glutamyl cleaving enzyme; gamma-glutamyltranspeptidase 5; gamma-glutamyltransferase-like activity 1; gamma-glutamyl transpeptidase-related enzyme; gamma-glutamyl transpeptidase-related protein; GGTLA1; GGT-REL
Cat.#:GGT5-4879HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GGT5 Protein, GST-tagged
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Cat.#:GGT5-1145HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GGT5 protein, His & T7-tagged
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Cat.#:GGT5-13244HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GGT5, GST-tagged
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Cat.#:GGT5-773HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human GGT5 Protein, His-tagged
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Cat.#:GGT5-702HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GGT5 cell lysate
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Involved Pathway

GGT5 involved in several pathways and played different roles in them. We selected most pathways GGT5 participated on our site, such as Taurine and hypotaurine metabolism, Cyanoamino acid metabolism, Glutathione metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Taurine and hypotaurine metabolism
ADOB; GGT1A; GAD1B; GGT5A; GAD1; ADO; CDO1; GGT1; GAD2; BAAT
Cyanoamino acid metabolism
GBA3; GGT1A; GGT7; GGT5; GGT5A; GGT1; SHMT2; GGT6; SHMT1
Glutathione metabolism
GCLM; GSTA4; MGST3; GSTM3; GSTA1; GPX5; SMS; GSR; ANPEPB; GPX1
Arachidonic acid metabolism
ALOX5A; ALOX8; ALOX15; CYP2P10; PLA2G10; CYP2AD2; PTGES2; FAAH2; CYP2C70; PTGES3B
Metabolic pathways
DNMT3AB; ALAD; NT5C2B; TALDO1; ATP6V0A2B; AKR1C4; CYP2C45; PFAS; ALDH2; INPP5K

Protein Function

GGT5 has several biochemical functions, for example, gamma-glutamyltransferase activity, glutathione hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT5 itself. We selected most functions GGT5 had, and list some proteins which have the same functions with GGT5. You can find most of the proteins on our site.
Function
Related Protein
Function gamma-glutamyltransferase activity
Related Protein GGT6; GGT1; GGTLC1; GGT1A; GGT7; GGT5; GGT5A
Function glutathione hydrolase activity
Related Protein GGT7; GGT5; GGT6; GGT1

GGT5 Related Articles

Sket, P; Korbar, T; et al. Influence of 3 '-3 ' inversion of polarity site within d(TGGGGT) on inter quartet cation binding. JOURNAL OF MOLECULAR STRUCTURE 1075:49-52(2014).
Serizawa, M; Kusuhara, M; et al. Identification of Metabolic Signatures Associated with Erlotinib Resistance of Non-small Cell Lung Cancer Cells. ANTICANCER RESEARCH 34:2779-2787(2014).