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GLIS1

  • Official Full Name

    GLIS family zinc finger 1

  • Overview

    GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of;transcription (Kim et al., 2002 (PubMed 12042312)).
  • Synonyms

    GLIS1; GLIS family zinc finger 1; zinc finger protein GLIS1; FLJ36155; GLI-similar 1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GLIS1-115H Recombinant Human GLIS1 protein, arginine-tagged E.coli Arg
Human GLIS1-5901HCL Recombinant Human GLIS1 293 Cell Lysate HEK293 N/A
Human GLIS1-5332HF Recombinant Full Length Human GLIS1 Protein, GST-tagged In Vitro Cell Free System GST 620 amino acids
Human GLIS1-4962H Recombinant Human GLIS1 Protein, GST-tagged Wheat Germ GST
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GLIS1 Related Articles

GLIS1 involved in several pathways and played different roles in them. We selected most pathways GLIS1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GLIS1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

GLIS1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, metal ion binding, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GLIS1 itself. We selected most functions GLIS1 had, and list some proteins which have the same functions with GLIS1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II regulatory region sequence-specific DNA bindingATF5;JARID2;MYOG;BHLHA15;ZNF583;MEF2D;ZNF812;RELA;LEF1
metal ion bindingZNF559;TNNI3;TRIM27;UGP2;ZNF443;PRDM12B;TRMT1L;DEM1;GTSF1L
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingPPARG;HIF1A;SOX17;MAFGA;CSRNP3;ARID3A;TRP53;MAFG;MYOG
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific bindingCDX2;ARID5B;PURB;ETV6;AEBP1;HOXD9;VAX2;E2F7;BCL6AB

GLIS1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLIS1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLIS1.

Vadnais, C; Shooshtarizadeh, P; et al. Autocrine Activation of the Wnt/beta-Catenin Pathway by CUX1 and GLIS1 in Breast Cancers. BIOLOGY OPEN 3:937-946(2014).
Khalesi, E; Nakamura, H; et al. The Kruppel-like zinc finger transcription factor, GLI-similar 1, is regulated by hypoxia-inducible factors via non-canonical mechanisms. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 441:499-506(2013).
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